TRIM14 and IVNS1ABP

Number of citations of the paper that reports this interaction (PubMedID 29053956)
0

Data Source:
BioGRID (two hybrid)

		TRIM14	IVNS1ABP
Description		tripartite motif containing 14	influenza virus NS1A binding protein
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GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Membrane Cytoplasmic Vesicle Phagocytic Vesicle	Nucleus Nucleoplasm Transcription Regulator Complex Spliceosomal Complex Cytoplasm Cytosol Cytoskeleton Cul3-RING Ubiquitin Ligase Complex
	Molecular Function	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Metal Ion Binding Molecular Adaptor Activity Ubiquitin Protein Ligase Activity	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity
	Biological Process	Immune System Process Inflammatory Response Negative Regulation Of Viral Transcription Innate Immune Response Positive Regulation Of DNA-templated Transcription Protein K48-linked Deubiquitination	Transcription By RNA Polymerase III MRNA Processing RNA Splicing Response To Virus Negative Regulation Of Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Intrinsic Apoptotic Signaling Pathway
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Multiple sclerosis ( 31604244)	Lead levels ( 26025379)
Interacting Genes		85 interacting genes: ABCF3 ADAMTS12 ALG13 AP3M1 ATP1B1 ATP1B3 ATP2A2 ATP5PB ATP6V1H BYSL CARD9 CCDC125 CCDC57 CCDC6 CENPC CIB3 CKS1B CSPP1 DHX58 EIF3G ERCC3 ETFBKMT EXOC8 FAM50B FAT1 GOLGA2 GOLGA6L9 HERC3 HEXIM2 HNRNPF IHO1 ITM2A IVNS1ABP KAT2B KIF3A KIFC3 LAMTOR1 LNX1 MAPRE3 MITD1 MNAT1 MRPL24 MYO15B NCOR1 NDUFA9 NFAT5 NPC2 PCGF6 PDIA6 PHF11 PIM2 PLCG1 POLR1C POLR2G PPP2R3C PRDM6 PRKAB2 PRPF31 PTPN21 RAB5A RAB9A RAD51D RBM33 RLF RNF125 RNF20 SLF2 SMARCB1 SMIM3 SPG21 STK38 TAX1BP1 TMEM167A TRAF2 TSGA10 UBE2B UBE2N UNK VIM WDR35 WRNIP1 ZC4H2 ZFP36L2 ZGPAT ZNF652	11 interacting genes: AHR CHD3 ENO1 KLHL20 PFN2 POLR1H RPL6 SYNCRIP TRA2B TRIM14 VIM
Entrez ID		9830	10625
HPRD ID		05948	10004
Ensembl ID		ENSG00000106785	ENSG00000116679
Uniprot IDs		Q14142	Q9Y6Y0
PDB IDs		6JBM	5YY8 6N34 6N3H
Enriched GO Terms of Interacting Partners?			Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Nucleus RNA Binding Regulation Of Macromolecule Metabolic Process Cytosolic Aryl Hydrocarbon Receptor Complex Type II Interferon Binding Histone H3K4 Dimethyltransferase Activity Histone H3K27 Dimethyltransferase Activity Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Nuclear Aryl Hydrocarbon Receptor Complex Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Metabolic Process Cellular Response To Type II Interferon Protein K33-linked Ubiquitination Phagocytic Vesicle Cellular Response To 2,3,7,8-tetrachlorodibenzodioxine Phosphopyruvate Hydratase Complex Phosphopyruvate Hydratase Activity Termination Of RNA Polymerase I Transcription Histone H3K27 Trimethyltransferase Activity Response To Type II Interferon
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