IVNS1ABP and TRIM14

Number of citations of the paper that reports this interaction (PubMedID 29053956)
0

Data Source:
BioGRID (two hybrid)

		IVNS1ABP	TRIM14
Description		influenza virus NS1A binding protein	tripartite motif containing 14
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GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Spliceosomal Complex Cytoplasm Cytosol Cytoskeleton Cul3-RING Ubiquitin Ligase Complex	Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Membrane Cytoplasmic Vesicle Phagocytic Vesicle
	Molecular Function	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Metal Ion Binding Molecular Adaptor Activity Ubiquitin Protein Ligase Activity
	Biological Process	Transcription By RNA Polymerase III MRNA Processing RNA Splicing Response To Virus Negative Regulation Of Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Immune System Process Inflammatory Response Negative Regulation Of Viral Transcription Innate Immune Response Positive Regulation Of DNA-templated Transcription Protein K48-linked Deubiquitination
Pathways			Interferon gamma signaling
Drugs
Diseases
GWAS		Lead levels ( 26025379)	Multiple sclerosis ( 31604244)
Interacting Genes		11 interacting genes: AHR CHD3 ENO1 KLHL20 PFN2 POLR1H RPL6 SYNCRIP TRA2B TRIM14 VIM	85 interacting genes: ABCF3 ADAMTS12 ALG13 AP3M1 ATP1B1 ATP1B3 ATP2A2 ATP5PB ATP6V1H BYSL CARD9 CCDC125 CCDC57 CCDC6 CENPC CIB3 CKS1B CSPP1 DHX58 EIF3G ERCC3 ETFBKMT EXOC8 FAM50B FAT1 GOLGA2 GOLGA6L9 HERC3 HEXIM2 HNRNPF IHO1 ITM2A IVNS1ABP KAT2B KIF3A KIFC3 LAMTOR1 LNX1 MAPRE3 MITD1 MNAT1 MRPL24 MYO15B NCOR1 NDUFA9 NFAT5 NPC2 PCGF6 PDIA6 PHF11 PIM2 PLCG1 POLR1C POLR2G PPP2R3C PRDM6 PRKAB2 PRPF31 PTPN21 RAB5A RAB9A RAD51D RBM33 RLF RNF125 RNF20 SLF2 SMARCB1 SMIM3 SPG21 STK38 TAX1BP1 TMEM167A TRAF2 TSGA10 UBE2B UBE2N UNK VIM WDR35 WRNIP1 ZC4H2 ZFP36L2 ZGPAT ZNF652
Entrez ID		10625	9830
HPRD ID		10004	05948
Ensembl ID		ENSG00000116679	ENSG00000106785
Uniprot IDs		Q9Y6Y0	Q14142
PDB IDs		5YY8 6N34 6N3H	6JBM
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Nucleus RNA Binding Regulation Of Macromolecule Metabolic Process Cytosolic Aryl Hydrocarbon Receptor Complex Type II Interferon Binding Histone H3K4 Dimethyltransferase Activity Histone H3K27 Dimethyltransferase Activity Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Nuclear Aryl Hydrocarbon Receptor Complex Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Metabolic Process Cellular Response To Type II Interferon Protein K33-linked Ubiquitination Phagocytic Vesicle Cellular Response To 2,3,7,8-tetrachlorodibenzodioxine Phosphopyruvate Hydratase Complex Phosphopyruvate Hydratase Activity Termination Of RNA Polymerase I Transcription Histone H3K27 Trimethyltransferase Activity Response To Type II Interferon
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