IVNS1ABP and ENO1

Number of citations of the paper that reports this interaction (PubMedID 23825951)
49

Data Source:
BioGRID (two hybrid, affinity chromatography technology)

		IVNS1ABP	ENO1
Description		influenza virus NS1A binding protein	enolase 1
Image
GO Annotations	Cellular Component	Nucleus Nucleoplasm Transcription Regulator Complex Spliceosomal Complex Cytoplasm Cytosol Cytoskeleton Cul3-RING Ubiquitin Ligase Complex	Phosphopyruvate Hydratase Complex Extracellular Space Nucleus Nuclear Outer Membrane Cytoplasm Cytosol Plasma Membrane Cell Cortex Cell Surface Membrane M Band Extracellular Exosome
	Molecular Function	Protein Binding Ubiquitin-like Ligase-substrate Adaptor Activity	Magnesium Ion Binding RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Transcription Corepressor Binding DNA-binding Transcription Repressor Activity, RNA Polymerase II-specific DNA Binding Transcription Corepressor Activity RNA Binding Phosphopyruvate Hydratase Activity Protein Binding Lyase Activity Protein Homodimerization Activity Cadherin Binding Metal Ion Binding GTPase Binding
	Biological Process	Transcription By RNA Polymerase III MRNA Processing RNA Splicing Response To Virus Negative Regulation Of Protein Ubiquitination Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Intrinsic Apoptotic Signaling Pathway	Negative Regulation Of Transcription By RNA Polymerase II Gluconeogenesis Glycolytic Process Response To Virus Positive Regulation Of Plasminogen Activation Negative Regulation Of Cell Growth Negative Regulation Of DNA-templated Transcription Positive Regulation Of Muscle Contraction Canonical Glycolysis Negative Regulation Of Hypoxia-induced Intrinsic Apoptotic Signaling Pathway Positive Regulation Of ATP Biosynthetic Process
Pathways			Glycolysis Gluconeogenesis Manipulation of host energy metabolism
Drugs			Zinc Copper Artenimol Zinc acetate Zinc chloride Zinc sulfate, unspecified form
Diseases
GWAS		Lead levels ( 26025379)	Asthma ( 30929738) Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Blood protein levels ( 30072576) Feeling tense ( 29500382) Platelet count ( 32888494) Plateletcrit ( 27863252 32888494) Tonsillectomy ( 27182965 28928442) White blood cell count ( 32888494) White blood cell count (basophil) ( 27863252)
Interacting Genes		11 interacting genes: AHR CHD3 ENO1 KLHL20 PFN2 POLR1H RPL6 SYNCRIP TRA2B TRIM14 VIM	66 interacting genes: AGTPBP1 ALDOA AMBP ARID1B BCL6 BHLHE40 BRCA1 CBX5 CHEK2 CHKA CLK1 COL14A1 CYSLTR2 DES DRC2 DUX4 FANCA FHL1 FLNC FNDC3B FXR1 FYN GLIS3 GRB2 HDAC1 HEMGN HEY2 HK2 HSP90AB1 HSPB2 ITGB1 IVNS1ABP KDM2A LIG4 LINC01554 LONRF3 MCPH1 MED13 MYOC NCOR1 OGT P4HB PAF1 PCNA PDE4B PLG PPP2R5E RXFP3 SERPING1 SET SGCG SNAPC3 SRC SUMO2 SUMO4 TCAP TEAD1 TERT TRAPPC2 TTN TUBA1A UBE3A UPF2 YWHAQ YWHAZ ZBTB44
Entrez ID		10625	2023
HPRD ID		10004	01400
Ensembl ID		ENSG00000116679	ENSG00000074800
Uniprot IDs		Q9Y6Y0	A0A024R4F1 A0A2R8Y6G6 P06733
PDB IDs		5YY8 6N34 6N3H	2PSN 3B97 5JLZ 5LAX 5NI9 5NIG 5OCK 8TRL
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Metabolic Process Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Nucleus RNA Binding Regulation Of Macromolecule Metabolic Process Cytosolic Aryl Hydrocarbon Receptor Complex Type II Interferon Binding Histone H3K4 Dimethyltransferase Activity Histone H3K27 Dimethyltransferase Activity Regulation Of Gene Expression Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Nuclear Aryl Hydrocarbon Receptor Complex Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of MRNA Metabolic Process Cellular Response To Type II Interferon Protein K33-linked Ubiquitination Phagocytic Vesicle Cellular Response To 2,3,7,8-tetrachlorodibenzodioxine Phosphopyruvate Hydratase Complex Phosphopyruvate Hydratase Activity Termination Of RNA Polymerase I Transcription Histone H3K27 Trimethyltransferase Activity Response To Type II Interferon	Transmembrane Transporter Binding Nucleus Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of DNA-templated Transcription Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Intracellular Signal Transduction Animal Organ Development Organelle Organization Negative Regulation Of Immune Response Muscle Hypertrophy Developmental Process Negative Regulation Of Apoptotic Process Cytoskeletal Protein Binding Negative Regulation Of Programmed Cell Death Z Disc Titin-telethonin Complex Sarcomerogenesis Negative Regulation Of Transcription By RNA Polymerase II Muscle Structure Development Sarcomere Organization Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Signal Transduction Costamere Negative Regulation Of Macromolecule Metabolic Process Cellular Response To Stress Negative Regulation Of Metabolic Process T Cell Costimulation Identical Protein Binding Negative Regulation Of Biosynthetic Process Regulation Of Membrane Depolarization Regulation Of Metabolic Process Regulation Of Programmed Cell Death Skeletal Muscle Myosin Thick Filament Assembly Negative Regulation Of Cell Communication Negative Regulation Of Signaling Response To L-glutamate Regulation Of Gene Expression Rhythmic Process Sarcolemma Negative Regulation Of Rho Protein Signal Transduction Regulation Of DNA-templated Transcription Actomyosin Structure Organization Cellular Response To Platelet-derived Growth Factor Stimulus Regulation Of RNA Biosynthetic Process Myosin Filament Assembly Regulation Of Macromolecule Metabolic Process Regulation Of Macromolecule Biosynthetic Process Tubulin Binding Cytoskeleton Organization
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