TRIM14 and UNK

Number of citations of the paper that reports this interaction (PubMedID 29053956)
0

Data Source:
BioGRID (two hybrid)

		TRIM14	UNK
Description		tripartite motif containing 14	unk zinc finger
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Membrane Cytoplasmic Vesicle Phagocytic Vesicle	Cytoplasm
	Molecular Function	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Metal Ion Binding Molecular Adaptor Activity Ubiquitin Protein Ligase Activity	RNA Binding Zinc Ion Binding Ribosome Binding Metal Ion Binding MRNA CDS Binding
	Biological Process	Immune System Process Inflammatory Response Negative Regulation Of Viral Transcription Innate Immune Response Positive Regulation Of DNA-templated Transcription Protein K48-linked Deubiquitination	In Utero Embryonic Development Neuron Migration Regulation Of Translation Cell Morphogenesis Involved In Neuron Differentiation Negative Regulation Of Cytoplasmic Translation
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Multiple sclerosis ( 31604244)	Alanine aminotransferase levels ( 33547301) Eosinophil count ( 27863252 32888494) Eosinophil percentage of white cells ( 32888494) LDL cholesterol ( 30275531) Low density lipoprotein cholesterol levels ( 29083408) Mean spheric corpuscular volume ( 32888494) Multiple sclerosis ( 31604244) Sum eosinophil basophil counts ( 27863252)
Interacting Genes		85 interacting genes: ABCF3 ADAMTS12 ALG13 AP3M1 ATP1B1 ATP1B3 ATP2A2 ATP5PB ATP6V1H BYSL CARD9 CCDC125 CCDC57 CCDC6 CENPC CIB3 CKS1B CSPP1 DHX58 EIF3G ERCC3 ETFBKMT EXOC8 FAM50B FAT1 GOLGA2 GOLGA6L9 HERC3 HEXIM2 HNRNPF IHO1 ITM2A IVNS1ABP KAT2B KIF3A KIFC3 LAMTOR1 LNX1 MAPRE3 MITD1 MNAT1 MRPL24 MYO15B NCOR1 NDUFA9 NFAT5 NPC2 PCGF6 PDIA6 PHF11 PIM2 PLCG1 POLR1C POLR2G PPP2R3C PRDM6 PRKAB2 PRPF31 PTPN21 RAB5A RAB9A RAD51D RBM33 RLF RNF125 RNF20 SLF2 SMARCB1 SMIM3 SPG21 STK38 TAX1BP1 TMEM167A TRAF2 TSGA10 UBE2B UBE2N UNK VIM WDR35 WRNIP1 ZC4H2 ZFP36L2 ZGPAT ZNF652	4 interacting genes: ATXN1 PABPC1 RNF10 TRIM14
Entrez ID		9830	85451
HPRD ID		05948	19037
Ensembl ID		ENSG00000106785	ENSG00000132478
Uniprot IDs		Q14142	Q9C0B0
PDB IDs		6JBM
Enriched GO Terms of Interacting Partners?			Poly(U) RNA Binding Regulation Of Glial Cell Proliferation Positive Regulation Of RNA Metabolic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Gliogenesis Regulation Of Viral Process Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process POZ Domain Binding Postsynapse To Nucleus Signaling Pathway Extrinsic Component Of Postsynaptic Density Membrane MCRD-mediated MRNA Stability Complex Poly(G) Binding Regulation Of Nucleobase-containing Compound Metabolic Process Positive Regulation Of Metabolic Process Nuclear Inclusion Body Regulation Of RNA Metabolic Process Negative Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Neurogenesis Ubiquitin Protein Ligase Activity Ribosome-associated Ubiquitin-dependent Protein Catabolic Process Negative Regulation Of Schwann Cell Proliferation Positive Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay CRD-mediated MRNA Stabilization Positive Regulation Of Nuclear-transcribed MRNA Poly(A) Tail Shortening Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Negative Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Translation Activator Activity Regulation Of Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Nervous System Development Negative Regulation Of Viral Transcription Negative Regulation Of Glial Cell Proliferation Positive Regulation Of Cytoplasmic Translation Positive Regulation Of Myelination Regulation Of Viral Transcription Poly(A) Binding Regulation Of Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Positive Regulation Of Glial Cell Proliferation Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Protein K48-linked Deubiquitination Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Positive Regulation Of Viral Genome Replication Insulin-like Growth Factor Receptor Signaling Pathway Regulation Of Cytoplasmic Translation
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