TRIM14 and RLF

Number of citations of the paper that reports this interaction (PubMedID 29053956)
0

Data Source:
BioGRID (two hybrid)

		TRIM14	RLF
Description		tripartite motif containing 14	RLF zinc finger
Image			No pdb structure
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Membrane Cytoplasmic Vesicle Phagocytic Vesicle	Nucleus
	Molecular Function	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Metal Ion Binding Molecular Adaptor Activity Ubiquitin Protein Ligase Activity	DNA-binding Transcription Factor Activity, RNA Polymerase II-specific DNA-binding Transcription Activator Activity, RNA Polymerase II-specific DNA Binding Protein Binding Zinc Ion Binding Metal Ion Binding
	Biological Process	Immune System Process Inflammatory Response Negative Regulation Of Viral Transcription Innate Immune Response Positive Regulation Of DNA-templated Transcription Protein K48-linked Deubiquitination	Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Heterochromatin Formation Positive Regulation Of DNA-templated Transcription Positive Regulation Of Transcription By RNA Polymerase II
Pathways		Interferon gamma signaling
Drugs
Diseases
GWAS		Multiple sclerosis ( 31604244)	High density lipoprotein cholesterol levels ( 30498476) Post bronchodilator FEV1 ( 26634245) Post bronchodilator FEV1/FVC ratio ( 26634245)
Interacting Genes		85 interacting genes: ABCF3 ADAMTS12 ALG13 AP3M1 ATP1B1 ATP1B3 ATP2A2 ATP5PB ATP6V1H BYSL CARD9 CCDC125 CCDC57 CCDC6 CENPC CIB3 CKS1B CSPP1 DHX58 EIF3G ERCC3 ETFBKMT EXOC8 FAM50B FAT1 GOLGA2 GOLGA6L9 HERC3 HEXIM2 HNRNPF IHO1 ITM2A IVNS1ABP KAT2B KIF3A KIFC3 LAMTOR1 LNX1 MAPRE3 MITD1 MNAT1 MRPL24 MYO15B NCOR1 NDUFA9 NFAT5 NPC2 PCGF6 PDIA6 PHF11 PIM2 PLCG1 POLR1C POLR2G PPP2R3C PRDM6 PRKAB2 PRPF31 PTPN21 RAB5A RAB9A RAD51D RBM33 RLF RNF125 RNF20 SLF2 SMARCB1 SMIM3 SPG21 STK38 TAX1BP1 TMEM167A TRAF2 TSGA10 UBE2B UBE2N UNK VIM WDR35 WRNIP1 ZC4H2 ZFP36L2 ZGPAT ZNF652	7 interacting genes: CLK1 FBXL17 GCH1 PRPF40A RIT1 RIT2 TRIM14
Entrez ID		9830	6018
HPRD ID		05948	01614
Ensembl ID		ENSG00000106785	ENSG00000117000
Uniprot IDs		Q14142	Q13129
PDB IDs		6JBM
Enriched GO Terms of Interacting Partners?			GTPase Activity GTP Cyclohydrolase I Activity GTP Binding GDP Binding G Protein Activity Ras Protein Signal Transduction
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