TRIM14 and EIF3G

Number of citations of the paper that reports this interaction (PubMedID 29053956)
0

Data Source:
BioGRID (two hybrid)

		TRIM14	EIF3G
Description		tripartite motif containing 14	eukaryotic translation initiation factor 3 subunit G
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Mitochondrion Mitochondrial Outer Membrane Membrane Cytoplasmic Vesicle Phagocytic Vesicle	Nucleus Cytoplasm Cytosol Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 43S Preinitiation Complex Eukaryotic 48S Preinitiation Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Transcription Coactivator Activity Protein Binding Zinc Ion Binding Metal Ion Binding Molecular Adaptor Activity Ubiquitin Protein Ligase Activity	Nucleic Acid Binding RNA Binding Translation Initiation Factor Activity Protein Binding
	Biological Process	Immune System Process Inflammatory Response Negative Regulation Of Viral Transcription Innate Immune Response Positive Regulation Of DNA-templated Transcription Protein K48-linked Deubiquitination	Formation Of Cytoplasmic Translation Initiation Complex Cytoplasmic Translational Initiation Translation Translational Initiation Viral Translational Termination-reinitiation
Pathways		Interferon gamma signaling	L13a-mediated translational silencing of Ceruloplasmin expression Translation initiation complex formation Formation of a pool of free 40S subunits Formation of the ternary complex, and subsequently, the 43S complex Ribosomal scanning and start codon recognition GTP hydrolysis and joining of the 60S ribosomal subunit
Drugs
Diseases
GWAS		Multiple sclerosis ( 31604244)
Interacting Genes		85 interacting genes: ABCF3 ADAMTS12 ALG13 AP3M1 ATP1B1 ATP1B3 ATP2A2 ATP5PB ATP6V1H BYSL CARD9 CCDC125 CCDC57 CCDC6 CENPC CIB3 CKS1B CSPP1 DHX58 EIF3G ERCC3 ETFBKMT EXOC8 FAM50B FAT1 GOLGA2 GOLGA6L9 HERC3 HEXIM2 HNRNPF IHO1 ITM2A IVNS1ABP KAT2B KIF3A KIFC3 LAMTOR1 LNX1 MAPRE3 MITD1 MNAT1 MRPL24 MYO15B NCOR1 NDUFA9 NFAT5 NPC2 PCGF6 PDIA6 PHF11 PIM2 PLCG1 POLR1C POLR2G PPP2R3C PRDM6 PRKAB2 PRPF31 PTPN21 RAB5A RAB9A RAD51D RBM33 RLF RNF125 RNF20 SLF2 SMARCB1 SMIM3 SPG21 STK38 TAX1BP1 TMEM167A TRAF2 TSGA10 UBE2B UBE2N UNK VIM WDR35 WRNIP1 ZC4H2 ZFP36L2 ZGPAT ZNF652	29 interacting genes: ACD AIFM1 APP EIF3A EIF3B EIF3C EIF3D EIF3H EIF3K EIF5 EPB41 FAM9B GADD45G GOLGA2 LMNA MEOX2 METTL3 MIF4GD MPHOSPH6 OGT PALS2 PIN1 PKN2 POT1 PRKAG1 SMN1 SNCA TK1 TRIM14
Entrez ID		9830	8666
HPRD ID		05948	04886
Ensembl ID		ENSG00000106785	ENSG00000130811
Uniprot IDs		Q14142	O75821
PDB IDs		6JBM	2CQ0 2MJC 5K0Y 6YBS 6ZMW 7QP6 7QP7 8OZ0 8PJ1 8PJ2 8PJ3 8PJ4 8PJ5 8PJ6 8PPL 8XXM 8XXN 9BLN
Enriched GO Terms of Interacting Partners?			Formation Of Cytoplasmic Translation Initiation Complex Cytoplasmic Translational Initiation Eukaryotic Translation Initiation Factor 3 Complex Eukaryotic 48S Preinitiation Complex Eukaryotic 43S Preinitiation Complex Translational Initiation Translation Initiation Factor Activity Protein-containing Complex Assembly Protein-containing Complex Organization Eukaryotic Translation Initiation Factor 3 Complex, EIF3m Cellular Component Assembly Regulation Of Translational Initiation Protein-RNA Complex Assembly Regulation Of Translation Viral Translational Termination-reinitiation Translation Post-transcriptional Regulation Of Gene Expression Cytoplasm IRES-dependent Viral Translational Initiation Macromolecule Metabolic Process Macromolecule Biosynthetic Process Regulation Of Protein Metabolic Process RNA Binding Cytosol Telomere Assembly Protein Tetramerization Protein Metabolic Process Nucleus Phosphoprotein Binding Cap-dependent Translational Initiation Shelterin Complex Negative Regulation Of Protein Catabolic Process Telomerase Inhibitor Activity Establishment Of Protein Localization To Telomere Regulation Of Generation Of Precursor Metabolites And Energy Regulation Of Glycolytic Process Nuclear Telomere Cap Complex Positive Regulation Of Translation Positive Regulation Of Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Carbohydrate Catabolic Process Positive Regulation Of Biosynthetic Process Telomere Capping Protein-containing Complex Establishment Of Protein Localization To Organelle Regulation Of ATP Metabolic Process Positive Regulation Of Protein Metabolic Process Nuclear Body Regulation Of Purine Nucleotide Metabolic Process Regulation Of Protein Catabolic Process
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?