MAGOH and ALYREF

Number of citations of the paper that reports this interaction (PMID 11707413)
48

Data Source:
HPRD (in vitro)

		MAGOH	ALYREF
Gene Name		mago-nashi homolog, proliferation-associated (Drosophila)	Aly/REF export factor
Image
Gene Ontology Annotations	Cellular Component	Nucleus Nucleoplasm Cytosol Nuclear Speck Exon-exon Junction Complex Catalytic Step 2 Spliceosome	Transcription Export Complex Nucleus Nucleoplasm Cytosol Membrane Nuclear Speck Exon-exon Junction Complex Intracellular Membrane-bounded Organelle Extracellular Vesicular Exosome Catalytic Step 2 Spliceosome
	Molecular Function	Protein Binding Poly(A) RNA Binding	Nucleotide Binding Single-stranded DNA Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Splicing, Via Spliceosome Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Export From Nucleus Regulation Of Translation RNA Splicing Gene Expression MRNA 3'-end Processing	Regulation Of DNA Recombination MRNA Splicing, Via Spliceosome Osteoblast Differentiation Transcription From RNA Polymerase II Promoter Termination Of RNA Polymerase II Transcription MRNA Export From Nucleus RNA Splicing Gene Expression MRNA 3'-end Processing Replication Fork Processing Positive Regulation Of DNA-templated Transcription, Elongation Viral MRNA Export From Host Cell Nucleus
Pathways		Nonsense-Mediated Decay (NMD) Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) mRNA Splicing Processing of Capped Intron-Containing Pre-mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript mRNA Splicing - Major Pathway Transport of Mature Transcript to Cytoplasm Cleavage of Growing Transcript in the Termination Region RNA Polymerase II Transcription Termination mRNA 3'-end processing	Transport of Mature mRNA Derived from an Intronless Transcript Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing Transport of the SLBP Dependant Mature mRNA RNA Polymerase II Transcription Transport of Mature mRNA derived from an Intron-Containing Transcript Transport of Mature mRNAs Derived from Intronless Transcripts Transport of the SLBP independent Mature mRNA Cleavage of Growing Transcript in the Termination Region mRNA Splicing - Major Pathway mRNA 3'-end processing Transport of Mature Transcript to Cytoplasm RNA Polymerase II Transcription Termination
Drugs
Diseases
GWAS
Protein-Protein Interactions		11 interactors: ALYREF CORO1A EIF4A3 GOLGA2 IPO13 MAP1B NXF1 RBM8A TADA2A XIST YWHAQ	11 interactors: AKT1 DDX39B IL7R LEF1 MAGOH NXF1 RUNX2 THOC1 THOC6 THOC7 UPF3A
Entrez ID		4116	10189
HPRD ID		04005	09168
Ensembl ID		ENSG00000162385	ENSG00000183684
Uniprot IDs		B1ARP8 P61326	E9PB61 Q86V81
PDB IDs		1P27 2HYI 2J0Q 2J0S 2XB2 3EX7	3ULH
Enriched GO Terms of Interacting Partners?		MRNA Transport RNA Transport RNA Localization Intracellular Transport MRNA Export From Nucleus Nucleocytoplasmic Transport Establishment Of Localization In Cell RNA Export From Nucleus Nuclear Transport MRNA 3'-end Processing Cytoplasmic Transport Cellular Localization RNA 3'-end Processing Nuclear Export MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Transport Termination Of RNA Polymerase II Transcription RNA Splicing DNA-templated Transcription, Termination MRNA Processing Regulation Of Intracellular Transport Nuclear-transcribed MRNA Catabolic Process, Nonsense-mediated Decay Posttranscriptional Regulation Of Gene Expression Early Endosome To Recycling Endosome Transport MRNA Metabolic Process Uropod Organization RNA Processing Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process Regulation Of Tubulin Deacetylation Negative Regulation Of Vesicle Fusion RNA Catabolic Process Viral MRNA Export From Host Cell Nucleus Establishment Of Monopolar Cell Polarity Phagolysosome Assembly Poly(A)+ MRNA Export From Nucleus Nerve Growth Factor Signaling Pathway Transcription From RNA Polymerase II Promoter Mitochondrion Transport Along Microtubule Regulation Of Organelle Organization Regulation Of Translation Regulation Of Cellular Component Organization Negative Regulation Of Actin Nucleation Establishment Of Mitochondrion Localization Replication Fork Processing	MRNA Transport Nucleocytoplasmic Transport Nuclear Transport RNA Transport RNA Localization MRNA Export From Nucleus RNA Export From Nucleus Viral MRNA Export From Host Cell Nucleus Nuclear Export Cytoplasmic Transport Intracellular Transport Of Virus Intracellular Transport Gene Expression MRNA Metabolic Process RNA Splicing Establishment Of Localization In Cell Regulation Of Cell Cycle Checkpoint MRNA Processing Negative Regulation Of DNA Damage Checkpoint Positive Regulation Of Gene Expression Viral Life Cycle Cellular Localization Viral Process RNA Processing Regulation Of DNA Damage Checkpoint RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Biosynthetic Process Osteoblast Differentiation T Cell Differentiation Regulation Of Cell Cycle Process Nitrogen Compound Metabolic Process Positive Regulation Of DNA-templated Transcription, Elongation Negative Regulation Of Adaptive Immune Response B Cell Proliferation Lymphocyte Differentiation Positive Regulation Of Cell-cell Adhesion Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Cell Activation Regulation Of Translation Positive Regulation Of Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process T Cell Aggregation T Cell Activation Ossification Lymphocyte Aggregation Leukocyte Aggregation
Tagcloud ?		appearance bodies casc3 core correlate correlates cytoplasm cytoplasmic deregulation determining disassembly eif4aiii ejc exon fate foci granules junction loaded localizes mln51 movements onto overexpressed overexpressing rbm8a spliced unlike y14	ablated amyotrophic atg biosamples c9orf72 crosslinking dipeptide exclusive expansions export foci ggggcc ggggcc5 hnrnp inappropriate irreversible lateral licensing messenger missing proteome pulldown repeat rnase sclerosis sequester sequestration srsf2 ultraviolet
Tagcloud (Difference) ?		appearance bodies casc3 core correlate correlates cytoplasm cytoplasmic deregulation determining disassembly eif4aiii ejc exon fate granules junction loaded localizes mln51 movements onto overexpressed overexpressing rbm8a spliced unlike y14	ablated amyotrophic atg biosamples c9orf72 crosslinking dipeptide exclusive expansions export ggggcc ggggcc5 hnrnp inappropriate irreversible lateral licensing messenger missing proteome pulldown repeat rnase sclerosis sequester sequestration srsf2 ultraviolet
Tagcloud (Intersection) ?		foci