WWC1 and KIAA0513

Number of citations of the paper that reports this interaction (PMID 17010949)
2

Data Source:
HPRD (two hybrid, in vivo)

		WWC1	KIAA0513
Gene Name		WW and C2 domain containing 1	KIAA0513
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Ruffle Membrane Protein Complex Perinuclear Region Of Cytoplasm	Cytoplasm
	Molecular Function	Transcription Coactivator Activity Protein Binding Kinase Binding Protein Binding, Bridging Protein Complex Scaffold
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Cell Migration Establishment Of Cell Polarity Regulation Of Intracellular Transport Hippo Signaling Regulation Of Hippo Signaling Negative Regulation Of Hippo Signaling Positive Regulation Of MAPK Cascade Negative Regulation Of Organ Growth
Pathways		Signaling by Hippo
Drugs
Diseases
GWAS		Periodontal microbiota ( 22699663)	Amyotrophic lateral sclerosis ( 22959728)
Protein-Protein Interactions		13 interactors: AIFM1 CDC5L CDC73 DDN FAM219A FEZ1 FEZ2 HIST1H3A KIAA0513 LRIF1 MAPK6 PRKCZ TNIK	4 interactors: APP HAX1 INTS4 WWC1
Entrez ID		23286	9764
HPRD ID		10033	17192
Ensembl ID		ENSG00000113645	ENSG00000135709
Uniprot IDs		Q8IX03	B4DSS5 O60268
PDB IDs		2Z0U
Enriched GO Terms of Interacting Partners?		Regulation Of Nitrogen Compound Metabolic Process Actin Cytoskeleton Reorganization Generation Of Neurons Regulation Of Dendrite Morphogenesis Neurogenesis Regulation Of Cellular Process Regulation Of Metabolic Process Intracellular Signal Transduction Positive Regulation Of Interleukin-13 Secretion Positive Regulation Of Interleukin-5 Secretion Regulation Of Transcription, DNA-templated Regulation Of Dendrite Development Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Neuron Differentiation Regulation Of RNA Metabolic Process Cell Projection Organization Cellular Metabolic Process Positive Regulation Of Interleukin-10 Secretion Positive Regulation Of T-helper 2 Cell Cytokine Production Nucleobase-containing Compound Metabolic Process Response To Stimulus Protein Localization To Plasma Membrane Cell Differentiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Activation Of Phospholipase D Activity Nervous System Development Regulation Of Gene Expression Transcription, DNA-templated Cellular Response To Stimulus Cell Cycle Neuron Projection Morphogenesis Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Positive Regulation Of Interleukin-13 Production DNA Packaging Signal Transduction Regulation Of Apoptotic DNA Fragmentation Positive Regulation Of Interleukin-5 Production Positive Regulation Of Cellular Metabolic Process Positive Regulation Of T Cell Cytokine Production Histone H2B Ubiquitination Regulation Of Cell Differentiation Plasma Membrane Organization Positive Regulation Of T-helper 2 Cell Differentiation DNA Replication-dependent Nucleosome Assembly Activation Of JNKK Activity Nitrogen Compound Metabolic Process	Synaptic Growth At Neuromuscular Junction Regulation Of Peptidyl-tyrosine Phosphorylation Collateral Sprouting In Absence Of Injury Regulation Of Protein Targeting To Mitochondrion Regulation Of Phosphorylation Collateral Sprouting Axon Midline Choice Point Recognition Regulation Of Developmental Growth Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Negative Regulation Of Hippo Signaling Regulation Of Phosphorus Metabolic Process Axon Choice Point Recognition Regulation Of Hippo Signaling Positive Regulation Of Granulocyte Differentiation Neuron Remodeling Regulation Of Cellular Amino Acid Metabolic Process Regulation Of Mitochondrion Degradation Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Intracellular Transport Positive Regulation Of Actin Cytoskeleton Reorganization Regulation Of Cellular Ketone Metabolic Process Cellular Copper Ion Homeostasis Copper Ion Homeostasis Suckling Behavior Regulation Of Growth Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Hippo Signaling Positive Regulation Of Cellular Metabolic Process Neuron Maturation MRNA Polyadenylation Regulation Of Epidermal Growth Factor-activated Receptor Activity SnRNA Processing Mating Behavior Regulation Of Signal Transduction Endoplasmic Reticulum Calcium Ion Homeostasis RNA Polyadenylation Neuron Recognition Negative Regulation Of Organ Growth SnRNA Metabolic Process Regulation Of Actin Cytoskeleton Reorganization Positive Regulation Of Intracellular Signal Transduction Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway
Tagcloud ?		contextdependent crossroads fat1 fat2 fat3 fat4 fathippo frmd1 frmd6 gammasecretase lamellipodia membraneassociated mob1a mob1b mpdz mpp5 mupp1 pals1 preball prognostics sav1 scribblebinding stemcell stk3 stk4 vapsbinding wwc2 wwtr1 yap1
Tagcloud (Difference) ?		contextdependent crossroads fat1 fat2 fat3 fat4 fathippo frmd1 frmd6 gammasecretase lamellipodia membraneassociated mob1a mob1b mpdz mpp5 mupp1 pals1 preball prognostics sav1 scribblebinding stemcell stk3 stk4 vapsbinding wwc2 wwtr1 yap1
Tagcloud (Intersection) ?