WWC1 and FAM219A

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
HPRD (two hybrid)

		WWC1	FAM219A
Gene Name		WW and C2 domain containing 1	family with sequence similarity 219, member A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Ruffle Membrane Protein Complex Perinuclear Region Of Cytoplasm
	Molecular Function	Transcription Coactivator Activity Protein Binding Kinase Binding Protein Binding, Bridging Protein Complex Scaffold
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Cell Migration Establishment Of Cell Polarity Regulation Of Intracellular Transport Hippo Signaling Regulation Of Hippo Signaling Negative Regulation Of Hippo Signaling Positive Regulation Of MAPK Cascade Negative Regulation Of Organ Growth
Pathways		Signaling by Hippo
Drugs
Diseases
GWAS		Periodontal microbiota ( 22699663)
Protein-Protein Interactions		13 interactors: AIFM1 CDC5L CDC73 DDN FAM219A FEZ1 FEZ2 HIST1H3A KIAA0513 LRIF1 MAPK6 PRKCZ TNIK	6 interactors: CSNK1G1 NIPSNAP3A PDE6D POLA2 SPRY2 WWC1
Entrez ID		23286	203259
HPRD ID		10033	12950
Ensembl ID		ENSG00000113645	ENSG00000164970
Uniprot IDs		Q8IX03	Q8IW50
PDB IDs		2Z0U
Enriched GO Terms of Interacting Partners?		Regulation Of Nitrogen Compound Metabolic Process Actin Cytoskeleton Reorganization Generation Of Neurons Regulation Of Dendrite Morphogenesis Neurogenesis Regulation Of Cellular Process Regulation Of Metabolic Process Intracellular Signal Transduction Positive Regulation Of Interleukin-13 Secretion Positive Regulation Of Interleukin-5 Secretion Regulation Of Transcription, DNA-templated Regulation Of Dendrite Development Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Neuron Differentiation Regulation Of RNA Metabolic Process Cell Projection Organization Cellular Metabolic Process Positive Regulation Of Interleukin-10 Secretion Positive Regulation Of T-helper 2 Cell Cytokine Production Nucleobase-containing Compound Metabolic Process Response To Stimulus Protein Localization To Plasma Membrane Cell Differentiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Activation Of Phospholipase D Activity Nervous System Development Regulation Of Gene Expression Transcription, DNA-templated Cellular Response To Stimulus Cell Cycle Neuron Projection Morphogenesis Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Positive Regulation Of Interleukin-13 Production DNA Packaging Signal Transduction Regulation Of Apoptotic DNA Fragmentation Positive Regulation Of Interleukin-5 Production Positive Regulation Of Cellular Metabolic Process Positive Regulation Of T Cell Cytokine Production Histone H2B Ubiquitination Regulation Of Cell Differentiation Plasma Membrane Organization Positive Regulation Of T-helper 2 Cell Differentiation DNA Replication-dependent Nucleosome Assembly Activation Of JNKK Activity Nitrogen Compound Metabolic Process
Tagcloud ?		contextdependent crossroads fat1 fat2 fat3 fat4 fathippo frmd1 frmd6 gammasecretase lamellipodia membraneassociated mob1a mob1b mpdz mpp5 mupp1 pals1 preball prognostics sav1 scribblebinding stemcell stk3 stk4 vapsbinding wwc2 wwtr1 yap1
Tagcloud (Difference) ?		contextdependent crossroads fat1 fat2 fat3 fat4 fathippo frmd1 frmd6 gammasecretase lamellipodia membraneassociated mob1a mob1b mpdz mpp5 mupp1 pals1 preball prognostics sav1 scribblebinding stemcell stk3 stk4 vapsbinding wwc2 wwtr1 yap1
Tagcloud (Intersection) ?