WWC1 and LRIF1

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		WWC1	LRIF1
Gene Name		WW and C2 domain containing 1	ligand dependent nuclear receptor interacting factor 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Ruffle Membrane Protein Complex Perinuclear Region Of Cytoplasm	Nucleus Microtubule Organizing Center Actin Cytoskeleton Nuclear Matrix
	Molecular Function	Transcription Coactivator Activity Protein Binding Kinase Binding Protein Binding, Bridging Protein Complex Scaffold	Protein Binding Retinoic Acid Receptor Binding
	Biological Process	Negative Regulation Of Transcription From RNA Polymerase II Promoter Transcription, DNA-templated Cell Migration Establishment Of Cell Polarity Regulation Of Intracellular Transport Hippo Signaling Regulation Of Hippo Signaling Negative Regulation Of Hippo Signaling Positive Regulation Of MAPK Cascade Negative Regulation Of Organ Growth	Transcription, DNA-templated Regulation Of Transcription, DNA-templated
Pathways		Signaling by Hippo
Drugs
Diseases
GWAS		Periodontal microbiota ( 22699663)
Protein-Protein Interactions		13 interactors: AIFM1 CDC5L CDC73 DDN FAM219A FEZ1 FEZ2 HIST1H3A KIAA0513 LRIF1 MAPK6 PRKCZ TNIK	129 interactors: AKR1C3 ANKRD24 ANXA1 ANXA7 APLP1 ARL3 ATF3 ATP1B1 BARD1 BMI1 BOC BRD7 BRMS1 CALR CBX1 CBX5 CCDC106 CDC42 CDKN1A CDKN2C CETN3 CHD3 CKMT2 COX17 CPE CRADD CRCT1 DDIT4 EIF6 ESR1 ETHE1 FAS FEZ1 FXR1 GADD45G GC GIT1 GPRASP2 GSTM4 HAP1 HIST3H3 HLA-DQA1 HMGB1 HMOX2 HSPB1 HSPB3 HSPBP1 HSPE1 ID2 IMMT KAT5 KAT7 KBTBD7 KCNE3 KLHL20 KLK10 LAMA4 LAMTOR5 MAD2L1BP MLLT3 MNAT1 MOB4 MPHOSPH6 MRPS12 MRPS6 NACA NHP2L1 NOC2L NR3C1 NRBP1 PAEP PAFAH1B3 PCDHA4 PDCD5 PFDN1 PFN1 PIAS4 PIN1 PLEKHA4 PNP POLR2C POLR3F PPARG PQBP1 PRMT1 PSG9 PSMD11 PSMD2 PSPC1 RAB27A RAP1B RARA RBM5 RCC1 RFC5 RHOH RIT1 RNF10 RORA RPA2 RPL37A RPLP1 RRM1 S100A8 SAT1 SELENBP1 SERPINB9 SETDB1 SMN1 SNRPN SPG7 STX5 SULT1E1 SUPT4H1 SUV39H2 TAF1D TDGF1 TGIF1 THRB TK1 TRBV2 TRDMT1 TSC22D1 TSPAN6 UBE2V2 VIM WDR62 WWC1 ZNF24
Entrez ID		23286	55791
HPRD ID		10033	17975
Ensembl ID		ENSG00000113645	ENSG00000121931
Uniprot IDs		Q8IX03	Q5T3J3
PDB IDs		2Z0U
Enriched GO Terms of Interacting Partners?		Regulation Of Nitrogen Compound Metabolic Process Actin Cytoskeleton Reorganization Generation Of Neurons Regulation Of Dendrite Morphogenesis Neurogenesis Regulation Of Cellular Process Regulation Of Metabolic Process Intracellular Signal Transduction Positive Regulation Of Interleukin-13 Secretion Positive Regulation Of Interleukin-5 Secretion Regulation Of Transcription, DNA-templated Regulation Of Dendrite Development Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Neuron Differentiation Regulation Of RNA Metabolic Process Cell Projection Organization Cellular Metabolic Process Positive Regulation Of Interleukin-10 Secretion Positive Regulation Of T-helper 2 Cell Cytokine Production Nucleobase-containing Compound Metabolic Process Response To Stimulus Protein Localization To Plasma Membrane Cell Differentiation Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Gene Expression Activation Of Phospholipase D Activity Nervous System Development Regulation Of Gene Expression Transcription, DNA-templated Cellular Response To Stimulus Cell Cycle Neuron Projection Morphogenesis Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Positive Regulation Of Interleukin-13 Production DNA Packaging Signal Transduction Regulation Of Apoptotic DNA Fragmentation Positive Regulation Of Interleukin-5 Production Positive Regulation Of Cellular Metabolic Process Positive Regulation Of T Cell Cytokine Production Histone H2B Ubiquitination Regulation Of Cell Differentiation Plasma Membrane Organization Positive Regulation Of T-helper 2 Cell Differentiation DNA Replication-dependent Nucleosome Assembly Activation Of JNKK Activity Nitrogen Compound Metabolic Process	Negative Regulation Of Cellular Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Cell Death Regulation Of Apoptotic Process Nitrogen Compound Metabolic Process Regulation Of Metabolic Process Positive Regulation Of Cellular Metabolic Process Positive Regulation Of Metabolic Process Negative Regulation Of Gene Expression Gene Expression Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Protein Metabolic Process Heterocycle Metabolic Process Positive Regulation Of Protein Metabolic Process System Development Regulation Of Gene Expression Developmental Process Regulation Of Cellular Protein Metabolic Process RNA Metabolic Process Multicellular Organismal Development Negative Regulation Of Biosynthetic Process RNA Biosynthetic Process Anatomical Structure Development Negative Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Cell Death Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Cellular Protein Metabolic Process Response To Stimulus Nervous System Development Transcription, DNA-templated Cellular Macromolecule Biosynthetic Process Negative Regulation Of Transcription, DNA-templated Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Programmed Cell Death Macromolecule Biosynthetic Process Response To Organic Substance Cellular Metabolic Process Response To Stress Positive Regulation Of Apoptotic Process Response To Steroid Hormone Biosynthetic Process Transcription Initiation From RNA Polymerase II Promoter Cellular Response To Steroid Hormone Stimulus DNA-templated Transcription, Initiation Regulation Of Cell Cycle Process Regulation Of G1/S Transition Of Mitotic Cell Cycle Regulation Of Cell Cycle G1/S Phase Transition Cellular Response To Organic Substance Regulation Of Cell Cycle
Tagcloud ?		contextdependent crossroads fat1 fat2 fat3 fat4 fathippo frmd1 frmd6 gammasecretase lamellipodia membraneassociated mob1a mob1b mpdz mpp5 mupp1 pals1 preball prognostics sav1 scribblebinding stemcell stk3 stk4 vapsbinding wwc2 wwtr1 yap1	aging apply characterizing composition dysfunctional enrich immunopurified involves isolation isotope labelling polypeptides pot1 qtip shelterin shelterins silac smchd1 states syndromes telomere telomeres telomeric tho tin2 tpp1 trf1 tumourigenesis validate
Tagcloud (Difference) ?		contextdependent crossroads fat1 fat2 fat3 fat4 fathippo frmd1 frmd6 gammasecretase lamellipodia membraneassociated mob1a mob1b mpdz mpp5 mupp1 pals1 preball prognostics sav1 scribblebinding stemcell stk3 stk4 vapsbinding wwc2 wwtr1 yap1	aging apply characterizing composition dysfunctional enrich immunopurified involves isolation isotope labelling polypeptides pot1 qtip shelterin shelterins silac smchd1 states syndromes telomere telomeres telomeric tho tin2 tpp1 trf1 tumourigenesis validate
Tagcloud (Intersection) ?