VPS4B and CHMP2A

Number of citations of the paper that reports this interaction (PMID 15173323)
16

Data Source:
HPRD (in vitro, two hybrid)

		VPS4B	CHMP2A
Gene Name		vacuolar protein sorting 4 homolog B (S. cerevisiae)	charged multivesicular body protein 2A
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Lysosome Endosome Early Endosome Late Endosome Vacuolar Membrane Centrosome Cytosol Endosome Membrane Late Endosome Membrane Extracellular Vesicular Exosome Flemming Body	Cytosol Membrane Late Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding ATP Binding Protein C-terminus Binding Microtubule-severing ATPase Activity ATPase Activity ATPase Activity, Coupled	Protein Binding Protein Domain Specific Binding
	Biological Process	Cell Separation After Cytokinesis Potassium Ion Transport Nucleus Organization Endosome Organization Vacuole Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Viral Process Endosomal Transport Viral Life Cycle Cytoplasmic Microtubule Organization Intracellular Cholesterol Transport Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Response To Lipid Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Viral Process Negative Regulation Of Cell Death Membrane Organization Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Negative Regulation Of Exosomal Secretion Positive Regulation Of Exosomal Secretion Positive Regulation Of Centriole Elongation	Cell Separation After Cytokinesis Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Viral Process Endosomal Transport Viral Life Cycle Viral Budding Via Host ESCRT Complex Establishment Of Protein Localization Regulation Of Viral Process Negative Regulation Of Cell Death Membrane Organization Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Positive Regulation Of Exosomal Secretion Negative Regulation Of Centriole Elongation
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle	HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CHMP1A CHMP1B CHMP2A CHMP5 HTRA2 VPS4A ZFYVE19	12 interactors: CHMP3 DOCK8 E2F4 EIF2B5 MITD1 NOL4 STAMBP TGFB3 USP54 USP8 VPS4A VPS4B
Entrez ID		9525	27243
HPRD ID		15653	12520
Ensembl ID		ENSG00000119541	ENSG00000130724
Uniprot IDs		O75351	O43633
PDB IDs		1WR0 1XWI 2CPT 2JQH 2JQK
Enriched GO Terms of Interacting Partners?		Cell Separation After Cytokinesis Mitotic Metaphase Plate Congression Metaphase Plate Congression Regulation Of Mitotic Spindle Assembly Establishment Of Chromosome Localization Regulation Of Spindle Assembly Regulation Of Mitotic Spindle Organization Mitotic Sister Chromatid Segregation Regulation Of Cell Division Sister Chromatid Segregation Nucleus Organization Regulation Of Cell Cycle Cell Division Regulation Of Centrosome Duplication Regulation Of Centrosome Cycle Regulation Of Cell Cycle Process Chromosome Segregation Vacuolar Transport Mitotic Nuclear Division Establishment Of Organelle Localization Regulation Of Mitotic Nuclear Division Organelle Localization Regulation Of Microtubule Cytoskeleton Organization Regulation Of Microtubule-based Process Mitotic Cell Cycle Process Mitotic Cell Cycle Abscission Viral Budding Via Host ESCRT Complex Regulation Of Protein Complex Assembly Regulation Of Organelle Organization Viral Budding Negative Regulation Of Cytokinesis Chromosome Organization Regulation Of Mitotic Cell Cycle Cytokinesis Cell Cycle Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Negative Regulation Of Cell Cycle Regulation Of Cytoskeleton Organization Cell Cycle Protein Transport Viral Life Cycle Establishment Of Protein Localization Virion Assembly Intracellular Transport Endosomal Transport Organelle Organization Protein Localization Regulation Of Cellular Component Organization	Cell Separation After Cytokinesis Cell Division Cytokinesis Mitotic Cell Cycle Process Mitotic Cell Cycle Mitotic Cytokinesis Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cell Cycle Process Viral Budding Via Host ESCRT Complex Positive Regulation Of Viral Release From Host Cell Viral Budding Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Cell Cycle Regulation Of Viral Release From Host Cell Virion Assembly Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Mitotic Metaphase Plate Congression Viral Life Cycle Proteolysis Involved In Cellular Protein Catabolic Process Cellular Protein Catabolic Process Endosome Organization Metaphase Plate Congression Endosomal Transport Protein Catabolic Process Regulation Of Centrosome Duplication Establishment Of Chromosome Localization Regulation Of Cell Division Regulation Of Centrosome Cycle Proteolysis Positive Regulation Of Exocytosis Positive Regulation Of Secretion Cellular Macromolecule Catabolic Process Negative Regulation Of Exosomal Secretion Memory T Cell Proliferation Positive Regulation Of Centriole Elongation Positive Regulation Of Viral Process Mitotic Sister Chromatid Segregation Membrane Budding Sister Chromatid Segregation Negative Regulation Of Cell Death Positive Regulation Of Centriole Replication Detection Of Hypoxia Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Uterine Wall Breakdown Ovulation Cycle Process Vacuole Organization Protein Deubiquitination
Tagcloud ?		adm adriamycin arrb2 bigger cblb chip cryopreservation doubling effectors endoperoxide exocytosis exudation gliomas impulse ingestion mdr medip ontology pard6b pgp pkcalpha rh123 sgh snap47 tgfb1 vamp3 vamp4 verify wizened
Tagcloud (Difference) ?		adm adriamycin arrb2 bigger cblb chip cryopreservation doubling effectors endoperoxide exocytosis exudation gliomas impulse ingestion mdr medip ontology pard6b pgp pkcalpha rh123 sgh snap47 tgfb1 vamp3 vamp4 verify wizened
Tagcloud (Intersection) ?