VPS4B and CHMP1A

Number of citations of the paper that reports this interaction (PMID 14505570)
292

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		VPS4B	CHMP1A
Gene Name		vacuolar protein sorting 4 homolog B (S. cerevisiae)	charged multivesicular body protein 1A
Image
Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Lysosome Endosome Early Endosome Late Endosome Vacuolar Membrane Centrosome Cytosol Endosome Membrane Late Endosome Membrane Extracellular Vesicular Exosome Flemming Body	Condensed Nuclear Chromosome ESCRT III Complex Early Endosome Microtubule Organizing Center Endomembrane System Nuclear Matrix Extracellular Vesicular Exosome
	Molecular Function	Protein Binding ATP Binding Protein C-terminus Binding Microtubule-severing ATPase Activity ATPase Activity ATPase Activity, Coupled	Protein Binding Metallopeptidase Activity Zinc Ion Binding Protein Domain Specific Binding Protein Homodimerization Activity
	Biological Process	Cell Separation After Cytokinesis Potassium Ion Transport Nucleus Organization Endosome Organization Vacuole Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Viral Process Endosomal Transport Viral Life Cycle Cytoplasmic Microtubule Organization Intracellular Cholesterol Transport Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Response To Lipid Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Viral Process Negative Regulation Of Cell Death Membrane Organization Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Negative Regulation Of Exosomal Secretion Positive Regulation Of Exosomal Secretion Positive Regulation Of Centriole Elongation	Cytokinesis Cell Separation After Cytokinesis Transcription, DNA-templated Proteolysis Nucleus Organization Vacuolar Transport Mitotic Chromosome Condensation Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Vesicle-mediated Transport Gene Silencing Negative Regulation Of Transcription By Glucose Negative Regulation Of Transcription, DNA-templated Regulation Of Mitotic Spindle Assembly
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CHMP1A CHMP1B CHMP2A CHMP5 HTRA2 VPS4A ZFYVE19	9 interactors: CHMP1B KIAA1715 NR1I2 STAMBP UBE2I USP8 VPS4A VPS4B ZDHHC17
Entrez ID		9525	5119
HPRD ID		15653	01237
Ensembl ID		ENSG00000119541	ENSG00000131165
Uniprot IDs		O75351	A6NG32 Q9HD42
PDB IDs		1WR0 1XWI 2CPT 2JQH 2JQK	2JQ9 2YMB 4A5X
Enriched GO Terms of Interacting Partners?		Cell Separation After Cytokinesis Mitotic Metaphase Plate Congression Metaphase Plate Congression Regulation Of Mitotic Spindle Assembly Establishment Of Chromosome Localization Regulation Of Spindle Assembly Regulation Of Mitotic Spindle Organization Mitotic Sister Chromatid Segregation Regulation Of Cell Division Sister Chromatid Segregation Nucleus Organization Regulation Of Cell Cycle Cell Division Regulation Of Centrosome Duplication Regulation Of Centrosome Cycle Regulation Of Cell Cycle Process Chromosome Segregation Vacuolar Transport Mitotic Nuclear Division Establishment Of Organelle Localization Regulation Of Mitotic Nuclear Division Organelle Localization Regulation Of Microtubule Cytoskeleton Organization Regulation Of Microtubule-based Process Mitotic Cell Cycle Process Mitotic Cell Cycle Abscission Viral Budding Via Host ESCRT Complex Regulation Of Protein Complex Assembly Regulation Of Organelle Organization Viral Budding Negative Regulation Of Cytokinesis Chromosome Organization Regulation Of Mitotic Cell Cycle Cytokinesis Cell Cycle Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Negative Regulation Of Cell Cycle Regulation Of Cytoskeleton Organization Cell Cycle Protein Transport Viral Life Cycle Establishment Of Protein Localization Virion Assembly Intracellular Transport Endosomal Transport Organelle Organization Protein Localization Regulation Of Cellular Component Organization	Cell Division Cell Separation After Cytokinesis Mitotic Cell Cycle Process Cytokinesis Mitotic Cell Cycle Mitotic Metaphase Plate Congression Metaphase Plate Congression Establishment Of Chromosome Localization Cell Cycle Process Chromosome Segregation Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Budding Via Host ESCRT Complex Cell Cycle Mitotic Sister Chromatid Segregation Mitotic Nuclear Division Regulation Of Mitotic Spindle Assembly Sister Chromatid Segregation Viral Budding Regulation Of Spindle Assembly Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Nucleus Organization Regulation Of Mitotic Spindle Organization Ubiquitin-dependent Protein Catabolic Process Modification-dependent Protein Catabolic Process Proteolysis Involved In Cellular Protein Catabolic Process Virion Assembly Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Cellular Protein Catabolic Process Protein Catabolic Process Endosome Organization Regulation Of Cell Division Proteolysis Regulation Of Centrosome Duplication Mitotic Cytokinesis Regulation Of Centrosome Cycle Cellular Macromolecule Catabolic Process Establishment Of Organelle Localization Positive Regulation Of Exocytosis Catabolic Process Drug Export Negative Regulation Of Exosomal Secretion Positive Regulation Of Centriole Elongation Positive Regulation Of SUMO Transferase Activity Membrane Budding Organelle Localization Regulation Of Cell Cycle Process Vacuole Organization Protein Deubiquitination Positive Regulation Of Centriole Replication
Tagcloud ?		adm adriamycin arrb2 bigger cblb chip cryopreservation doubling effectors endoperoxide exocytosis exudation gliomas impulse ingestion mdr medip ontology pard6b pgp pkcalpha rh123 sgh snap47 tgfb1 vamp3 vamp4 verify wizened	aux1 auxin disorganized endosomal escrt gradients internalized lip5 lumenal meristems mislocalized multivesicular mvb mvbs pin1 pin2 pinformed1 protein1a resistant1 rudimentary seedling seedlings skd1 sorted stomata symmetry thaliana vacuolar
Tagcloud (Difference) ?		adm adriamycin arrb2 bigger cblb chip cryopreservation doubling effectors endoperoxide exocytosis exudation gliomas impulse ingestion mdr medip ontology pard6b pgp pkcalpha rh123 sgh snap47 tgfb1 vamp3 vamp4 verify wizened	aux1 auxin disorganized endosomal escrt gradients internalized lip5 lumenal meristems mislocalized multivesicular mvb mvbs pin1 pin2 pinformed1 protein1a resistant1 rudimentary seedling seedlings skd1 sorted stomata symmetry thaliana vacuolar
Tagcloud (Intersection) ?