VPS4B and ZFYVE19

Number of citations of the paper that reports this interaction (PMID 22939629)
44

Data Source:
BioGRID (two hybrid, biochemical)

		VPS4B	ZFYVE19
Gene Name		vacuolar protein sorting 4 homolog B (S. cerevisiae)	zinc finger, FYVE domain containing 19
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Lysosome Endosome Early Endosome Late Endosome Vacuolar Membrane Centrosome Cytosol Endosome Membrane Late Endosome Membrane Extracellular Vesicular Exosome Flemming Body	Cytoplasm Centrosome Midbody Cleavage Furrow
	Molecular Function	Protein Binding ATP Binding Protein C-terminus Binding Microtubule-severing ATPase Activity ATPase Activity ATPase Activity, Coupled	Protein Binding Zinc Ion Binding Phosphatidylinositol-3-phosphate Binding
	Biological Process	Cell Separation After Cytokinesis Potassium Ion Transport Nucleus Organization Endosome Organization Vacuole Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Viral Process Endosomal Transport Viral Life Cycle Cytoplasmic Microtubule Organization Intracellular Cholesterol Transport Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Response To Lipid Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Viral Process Negative Regulation Of Cell Death Membrane Organization Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Negative Regulation Of Exosomal Secretion Positive Regulation Of Exosomal Secretion Positive Regulation Of Centriole Elongation	Abscission Negative Regulation Of Cytokinesis Cell Division
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CHMP1A CHMP1B CHMP2A CHMP5 HTRA2 VPS4A ZFYVE19	6 interactors: CAPN7 CCHCR1 HTT MITD1 VPS4B ZDHHC17
Entrez ID		9525	84936
HPRD ID		15653	15731
Ensembl ID		ENSG00000119541	ENSG00000166140
Uniprot IDs		O75351	Q96K21
PDB IDs		1WR0 1XWI 2CPT 2JQH 2JQK
Enriched GO Terms of Interacting Partners?		Cell Separation After Cytokinesis Mitotic Metaphase Plate Congression Metaphase Plate Congression Regulation Of Mitotic Spindle Assembly Establishment Of Chromosome Localization Regulation Of Spindle Assembly Regulation Of Mitotic Spindle Organization Mitotic Sister Chromatid Segregation Regulation Of Cell Division Sister Chromatid Segregation Nucleus Organization Regulation Of Cell Cycle Cell Division Regulation Of Centrosome Duplication Regulation Of Centrosome Cycle Regulation Of Cell Cycle Process Chromosome Segregation Vacuolar Transport Mitotic Nuclear Division Establishment Of Organelle Localization Regulation Of Mitotic Nuclear Division Organelle Localization Regulation Of Microtubule Cytoskeleton Organization Regulation Of Microtubule-based Process Mitotic Cell Cycle Process Mitotic Cell Cycle Abscission Viral Budding Via Host ESCRT Complex Regulation Of Protein Complex Assembly Regulation Of Organelle Organization Viral Budding Negative Regulation Of Cytokinesis Chromosome Organization Regulation Of Mitotic Cell Cycle Cytokinesis Cell Cycle Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Negative Regulation Of Cell Cycle Regulation Of Cytoskeleton Organization Cell Cycle Protein Transport Viral Life Cycle Establishment Of Protein Localization Virion Assembly Intracellular Transport Endosomal Transport Organelle Organization Protein Localization Regulation Of Cellular Component Organization	Cell Separation After Cytokinesis Protein Transport Establishment Of Protein Localization Neural Plate Formation Negative Regulation Of Exosomal Secretion Positive Regulation Of Centriole Elongation Mitotic Cell Cycle Process Cytoplasmic Transport Positive Regulation Of Centriole Replication Serotonin Uptake Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Lactate Biosynthetic Process From Pyruvate Protein Localization Mitotic Cell Cycle Positive Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Negative Regulation Of Cerebellar Granule Cell Precursor Proliferation Regulation Of Protein Phosphatase Type 2A Activity Metal Ion Transport Quinolinate Biosynthetic Process Negative Regulation Of Synaptic Transmission, Dopaminergic Endosomal Transport Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Lactate Biosynthetic Process Regulation Of Inositol 1,4,5-trisphosphate-sensitive Calcium-release Channel Activity Positive Regulation Of Centrosome Duplication Endosome Transport Via Multivesicular Body Sorting Pathway Paraxial Mesoderm Formation Cell Cycle Process Quinolinate Metabolic Process Cellular Response To CGMP Viral Budding Via Host ESCRT Complex Nucleocytoplasmic Transport Nuclear Transport Response To CGMP Positive Regulation Of Viral Release From Host Cell Serotonin Transport Sperm Ejaculation Neural Plate Morphogenesis L-glutamate Import Regulation Of Mitotic Spindle Assembly Positive Regulation Of Cell Cycle Cation Transport Viral Budding Intracellular Cholesterol Transport Intracellular Sterol Transport Self Proteolysis Regulation Of Spindle Assembly Establishment Of Organelle Localization Citrulline Metabolic Process Positive Regulation Of Exosomal Secretion
Tagcloud ?		adm adriamycin arrb2 bigger cblb chip cryopreservation doubling effectors endoperoxide exocytosis exudation gliomas impulse ingestion mdr medip ontology pard6b pgp pkcalpha rh123 sgh snap47 tgfb1 vamp3 vamp4 verify wizened
Tagcloud (Difference) ?		adm adriamycin arrb2 bigger cblb chip cryopreservation doubling effectors endoperoxide exocytosis exudation gliomas impulse ingestion mdr medip ontology pard6b pgp pkcalpha rh123 sgh snap47 tgfb1 vamp3 vamp4 verify wizened
Tagcloud (Intersection) ?