VPS4B and CHMP1B

Number of citations of the paper that reports this interaction (PMID 14505570)
292

Data Source:
HPRD (in vitro)

		VPS4B	CHMP1B
Gene Name		vacuolar protein sorting 4 homolog B (S. cerevisiae)	charged multivesicular body protein 1B
Image
Gene Ontology Annotations	Cellular Component	Spindle Pole Nucleus Cytoplasm Lysosome Endosome Early Endosome Late Endosome Vacuolar Membrane Centrosome Cytosol Endosome Membrane Late Endosome Membrane Extracellular Vesicular Exosome Flemming Body	Cytosol Late Endosome Membrane Extracellular Vesicular Exosome
	Molecular Function	Protein Binding ATP Binding Protein C-terminus Binding Microtubule-severing ATPase Activity ATPase Activity ATPase Activity, Coupled	Protein Binding Protein Domain Specific Binding
	Biological Process	Cell Separation After Cytokinesis Potassium Ion Transport Nucleus Organization Endosome Organization Vacuole Organization Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Protein Transport Viral Process Endosomal Transport Viral Life Cycle Cytoplasmic Microtubule Organization Intracellular Cholesterol Transport Endosome To Lysosome Transport Via Multivesicular Body Sorting Pathway Response To Lipid Viral Budding Via Host ESCRT Complex Ubiquitin-dependent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Viral Process Negative Regulation Of Cell Death Membrane Organization Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Regulation Of Mitotic Spindle Assembly Positive Regulation Of Viral Release From Host Cell Negative Regulation Of Exosomal Secretion Positive Regulation Of Exosomal Secretion Positive Regulation Of Centriole Elongation	Cytokinesis Cell Separation After Cytokinesis Nucleus Organization Vacuolar Transport Mitotic Metaphase Plate Congression Regulation Of Centrosome Duplication Protein Transport Establishment Of Protein Localization Regulation Of Mitotic Spindle Assembly
Pathways		HIV Life Cycle Budding and maturation of HIV virion HIV Infection Endosomal Sorting Complex Required For Transport (ESCRT) Late Phase of HIV Life Cycle
Drugs
Diseases
GWAS
Protein-Protein Interactions		7 interactors: CHMP1A CHMP1B CHMP2A CHMP5 HTRA2 VPS4A ZFYVE19	16 interactors: CHMP1A CHMP4B CHMP5 CNOT10 KNSTRN RAB11A RASSF7 SNRNP200 SPAST SSRP1 STAMBP SUCLG1 USP54 USP8 VPS4A VPS4B
Entrez ID		9525	57132
HPRD ID		15653	12106
Ensembl ID		ENSG00000119541	ENSG00000255112
Uniprot IDs		O75351	Q7LBR1
PDB IDs		1WR0 1XWI 2CPT 2JQH 2JQK	3EAB
Enriched GO Terms of Interacting Partners?		Cell Separation After Cytokinesis Mitotic Metaphase Plate Congression Metaphase Plate Congression Regulation Of Mitotic Spindle Assembly Establishment Of Chromosome Localization Regulation Of Spindle Assembly Regulation Of Mitotic Spindle Organization Mitotic Sister Chromatid Segregation Regulation Of Cell Division Sister Chromatid Segregation Nucleus Organization Regulation Of Cell Cycle Cell Division Regulation Of Centrosome Duplication Regulation Of Centrosome Cycle Regulation Of Cell Cycle Process Chromosome Segregation Vacuolar Transport Mitotic Nuclear Division Establishment Of Organelle Localization Regulation Of Mitotic Nuclear Division Organelle Localization Regulation Of Microtubule Cytoskeleton Organization Regulation Of Microtubule-based Process Mitotic Cell Cycle Process Mitotic Cell Cycle Abscission Viral Budding Via Host ESCRT Complex Regulation Of Protein Complex Assembly Regulation Of Organelle Organization Viral Budding Negative Regulation Of Cytokinesis Chromosome Organization Regulation Of Mitotic Cell Cycle Cytokinesis Cell Cycle Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion Negative Regulation Of Cell Cycle Regulation Of Cytoskeleton Organization Cell Cycle Protein Transport Viral Life Cycle Establishment Of Protein Localization Virion Assembly Intracellular Transport Endosomal Transport Organelle Organization Protein Localization Regulation Of Cellular Component Organization	Cell Separation After Cytokinesis Mitotic Metaphase Plate Congression Cell Division Mitotic Sister Chromatid Segregation Metaphase Plate Congression Sister Chromatid Segregation Establishment Of Chromosome Localization Mitotic Cell Cycle Process Mitotic Cell Cycle Regulation Of Mitotic Spindle Assembly Regulation Of Spindle Assembly Cytokinesis Chromosome Segregation Regulation Of Mitotic Spindle Organization Cell Cycle Process Regulation Of Microtubule Cytoskeleton Organization Mitotic Nuclear Division Regulation Of Microtubule-based Process Cell Cycle Ubiquitin-independent Protein Catabolic Process Via The Multivesicular Body Sorting Pathway Viral Budding Via Host ESCRT Complex Nucleus Organization Regulation Of Centrosome Duplication Viral Budding Regulation Of Centrosome Cycle Establishment Of Organelle Localization Chromosome Organization Organelle Localization Endosomal Transport Virion Assembly Regulation Of Cell Cycle Process Regulation Of Cell Division Regulation Of Cytoskeleton Organization Endosome Organization Regulation Of Mitotic Nuclear Division Mitotic Cytokinesis Regulation Of Mitotic Cell Cycle Organelle Organization Viral Life Cycle Positive Regulation Of Viral Release From Host Cell Cellular Macromolecule Catabolic Process Positive Regulation Of Viral Process Regulation Of Organelle Organization Vacuolar Transport Regulation Of Cell Cycle Membrane Budding Viral Process Proteolysis Involved In Cellular Protein Catabolic Process Positive Regulation Of Exosomal Secretion Regulation Of Exosomal Secretion
Tagcloud ?		adm adriamycin arrb2 bigger cblb chip cryopreservation doubling effectors endoperoxide exocytosis exudation gliomas impulse ingestion mdr medip ontology pard6b pgp pkcalpha rh123 sgh snap47 tgfb1 vamp3 vamp4 verify wizened	aux1 auxin disorganized endosomal escrt gradients internalized lip5 lumenal meristems mislocalized multivesicular mvb mvbs pin1 pin2 pinformed1 protein1a resistant1 rudimentary seedling seedlings skd1 sorted stomata symmetry thaliana vacuolar
Tagcloud (Difference) ?		adm adriamycin arrb2 bigger cblb chip cryopreservation doubling effectors endoperoxide exocytosis exudation gliomas impulse ingestion mdr medip ontology pard6b pgp pkcalpha rh123 sgh snap47 tgfb1 vamp3 vamp4 verify wizened	aux1 auxin disorganized endosomal escrt gradients internalized lip5 lumenal meristems mislocalized multivesicular mvb mvbs pin1 pin2 pinformed1 protein1a resistant1 rudimentary seedling seedlings skd1 sorted stomata symmetry thaliana vacuolar
Tagcloud (Intersection) ?