GSTO1 and FILNC1

Number of citations of the paper that reports this interaction (PubMedID 28978906)
44

Data Source:
BioGRID (unspecified method)

		GSTO1	FILNC1
Description		glutathione S-transferase omega 1	FOXO induced long non-coding RNA 1
Image			No pdb structure
GO Annotations	Cellular Component	Cytoplasm Cytosol Extracellular Exosome
	Molecular Function	Glutathione Transferase Activity Protein Binding Oxidoreductase Activity Transferase Activity Glutathione Dehydrogenase (ascorbate) Activity Methylarsonate Reductase Activity
	Biological Process	Glutathione Metabolic Process Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Positive Regulation Of Skeletal Muscle Contraction By Regulation Of Release Of Sequestered Calcium Ion L-ascorbic Acid Metabolic Process Xenobiotic Catabolic Process Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Positive Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Cellular Response To Arsenic-containing Substance Cellular Oxidant Detoxification
Pathways		Methylation Glutathione conjugation Vitamin C (ascorbate) metabolism Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation
Drugs		Glutathione
Diseases
GWAS		Blood protein levels ( 30072576) Metabolite levels ( 23823483)	Heel bone mineral density x serum urate levels interaction ( 34046847)
Interacting Genes		10 interacting genes: APP CEP126 CFTR EEF1G FILNC1 HSPB1 KAT5 RBM48 SERPINB5 SETDB1	88 interacting genes: AAAS ABCC1 ACTN1 ACTR2 AHSA1 AIMP2 AKAP8 ALDH1B1 AP1B1 AP3D1 ARAP1 ARF6 ATP2A2 CAND1 CCT6B CLPX CNDP2 COPG1 DDX24 DNM1 DNM1L DPM1 DYNC1H1 EEF1D EEF2 ERLIN1 GALK1 GMPS GSTO1 HDLBP HNRNPA0 HNRNPD HSPA1A IDH1 KTN1 LAMC1 LAS1L MAP1S MCM3 MRPL4 MSH2 MTHFD1L MYL12A NIBAN2 NKRF NOP56 NPEPPSP1 NSF NUP153 OASL OGT PCAT1 PDCD4 PES1 PFAS PLS3 PPME1 PSMC2 PSMC4 PSMD14 PSMD5 PURA QNG1 RIGI RO60 RPL13A RPS5 RPSA SART1 STT3B STXBP2 TAGLN2 TIMM50 TMEM126A TMX3 TRIP13 TTLL12 TTN U2AF1 UBA52 UBE4A VPS35 WARS1 XPO1 XPOT XRCC6 YWHAB ZCCHC8
Entrez ID		9446	100132735
HPRD ID		10401
Ensembl ID		ENSG00000148834	ENSG00000231426
Uniprot IDs		P78417 V9HWG9
PDB IDs		1EEM 3LFL 3VLN 4IS0 4YQM 4YQU 4YQV 5UEH 5V3Q 5YVN 5YVO 6MHB 6MHC 6MHD 6PNM 6PNN 6PNO
Enriched GO Terms of Interacting Partners?		Acetylcholine Receptor Activator Activity Protein-folding Chaperone Binding Amyloid-beta Complex PTB Domain Binding Positive Regulation Of Interleukin-1 Production Growth Cone Lamellipodium Collateral Sprouting In Absence Of Injury Regulation Of Protein Import Axo-dendritic Transport Regulation Of Response To Calcium Ion Positive Regulation Of Tumor Necrosis Factor Production Amylin Binding Endosome To Plasma Membrane Transport Vesicle Positive Regulation Of Toll Signaling Pathway Positive Regulation Of Endothelin Production Growth Cone Filopodium Cellular Response To CAMP Positive Regulation Of Interleukin-1 Beta Production Lipoprotein Particle Serine-type Endopeptidase Inhibitor Activity Microtubule-based Process Phospholipase D-activating G Protein-coupled Receptor Signaling Pathway Positive Regulation Of Protein Import Microglia Development Positive Regulation Of G Protein-coupled Receptor Internalization Response To CAMP Regulation Of Interleukin-1 Beta Production Positive Regulation Of Anion Channel Activity Intracellularly ATP-gated Chloride Channel Activity Positive Regulation Of Voltage-gated Chloride Channel Activity Sec61 Translocon Complex Binding Positive Regulation Of Monoatomic Anion Transport Negative Regulation Of Protein Kinase C Signaling Protein Kinase C Inhibitor Activity Cornified Envelope Histone H2AK5 Acetyltransferase Activity Peptide Butyryltransferase Activity Peptide 2-hydroxyisobutyryltransferase Activity Peptide Crotonyltransferase Activity Histone H2A Acetyltransferase Activity Peptide Lactyltransferase (CoA-dependent) Activity Positive Regulation Of Tumor Necrosis Factor Superfamily Cytokine Production Response To Norepinephrine Regulation Of Endoplasmic Reticulum Stress-induced Neuron Intrinsic Apoptotic Signaling Pathway Regulation Of Interleukin-1 Production Cellular Response To Norepinephrine Stimulus Chromatin Binding Astrocyte Activation Involved In Immune Response Low-density Lipoprotein Particle Mediated Signaling Positive Regulation Of Enamel Mineralization	RNA Binding Cytosol ATP Hydrolysis Activity Nucleotide Binding Cadherin Binding Ribonucleoprotein Complex Ficolin-1-rich Granule Lumen ATP Binding Extracellular Exosome Proteasome Accessory Complex Cytoplasm Translation Intracellular Transport Proteasome Regulatory Particle, Base Subcomplex Secretory Granule Lumen Nucleoplasm Actin Filament Binding Macromolecule Metabolic Process Nucleolus Mitochondrion-derived Vesicle Intracellular Protein Transport Organelle Localization Cellular Localization Establishment Of Localization In Cell Proteasome Complex Nucleobase-containing Compound Metabolic Process Actin Filament Network Formation ATP-dependent Protein Disaggregase Activity Proteasome-activating Activity LncRNA Binding Membrane Coat Ribosome Cytoplasmic Translation Establishment Of Organelle Localization Double-stranded DNA Binding Regulation Of Proteasomal Protein Catabolic Process Regulation Of Protein Catabolic Process Establishment Of Protein Localization ATP-dependent Protein Folding Chaperone Cellular Component Assembly Regulation Of Cytoplasmic Translation
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