QKI and THAP1

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		QKI	THAP1
Gene Name		QKI, KH domain containing, RNA binding	THAP domain containing, apoptosis associated protein 1
Image
Gene Ontology Annotations	Cellular Component	Nucleus Cytoplasm	Nucleus PML Body
	Molecular Function	MRNA Binding Protein Binding SH3 Domain Binding Poly(A) RNA Binding	Protein Binding Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Vasculogenesis MRNA Processing Regulation Of Translation Spermatid Development RNA Splicing Positive Regulation Of Gene Expression Myelination Muscle Cell Differentiation Long-chain Fatty Acid Biosynthetic Process MRNA Transport 3'-UTR-mediated MRNA Destabilization	Endothelial Cell Proliferation Transcription, DNA-templated Regulation Of Transcription, DNA-templated Cell Cycle Regulation Of Mitotic Cell Cycle
Pathways
Drugs
Diseases
GWAS		Response to TNF antagonist treatment ( 18615156)
Protein-Protein Interactions		34 interactors: APP ATXN1 C10orf10 CARM1 DAZ1 DAZ4 FUBP3 HCLS1 HNRNPH2 HNRNPK HNRNPLL IL7R NABP1 PCBP1 PCBP2 PCBP4 PRMT1 PSMF1 PTBP1 PTBP2 RALY RBFOX1 RBFOX2 RBM11 RBM14 RBM23 RBPMS RNF138 SERF2 SNRPA THAP1 U2AF2 USH1C WDR77	58 interactors: ACOT7 AKAP17A AKAP9 AP2B1 ARL6IP4 BAG5 BMS1P5 BYSL C11orf57 C1orf35 C7orf50 CHD2 CSNK2A1 DCAF8 DVL2 FAM124A FAM133A FXR2 GPATCH2L HNRNPLL KLF12 KRTAP10-7 LASP1 MORF4L1 MORF4L2 MRPL11 NKAP NUP62 PAWR PHF1 PID1 POLR2L POLR2M PPIG PRKAA1 PRR20A QKI RALYL RBM39 RIPPLY1 RP9P RPS25 SAP30BP SERF2 SLU7 STRBP TCEA2 TPM3 TRAF5 TRIM26 TTLL10 TXN2 U2AF2 WDYHV1 YES1 ZCCHC10 ZNF385C ZNF408
Entrez ID		9444	55145
HPRD ID		06691	15496
Ensembl ID		ENSG00000112531	ENSG00000131931
Uniprot IDs		Q8WY44 Q96PU8	Q9NVV9
PDB IDs		4JVH	2JTG 2KO0 2L1G
Enriched GO Terms of Interacting Partners?		RNA Processing MRNA Processing MRNA Metabolic Process RNA Splicing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Gene Expression RNA Metabolic Process Regulation Of RNA Splicing Cellular Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of MRNA Splicing, Via Spliceosome Intracellular Estrogen Receptor Signaling Pathway Regulation Of RNA Metabolic Process Negative Regulation Of RNA Splicing Neuromuscular Process Controlling Balance Regulation Of MRNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Cellular Metabolic Process Positive Regulation Of Gene Expression Neuromuscular Process Peptidyl-arginine Methylation, To Asymmetrical-dimethyl Arginine Regulation Of Metabolic Process Intracellular Steroid Hormone Receptor Signaling Pathway Peptidyl-arginine N-methylation Intracellular Receptor Signaling Pathway Histone Arginine Methylation Negative Regulation Of MRNA Splicing, Via Spliceosome Peptidyl-arginine Methylation Positive Regulation Of Cellular Metabolic Process Cellular Process Positive Regulation Of Metabolic Process Positive Regulation Of RNA Splicing Histone H3-R17 Methylation Regulation Of Myeloid Cell Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Mitotic Cell Cycle Histone H3-R2 Methylation Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction Parallel Actin Filament Bundle Assembly Interleukin-7-mediated Signaling Pathway Positive Regulation Of Macromolecule Biosynthetic Process Visual Learning Visual Behavior	RNA Metabolic Process Gene Expression Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Biosynthetic Process Nitrogen Compound Metabolic Process Transcription, DNA-templated Cellular Metabolic Process Regulation Of Gene Expression RNA Splicing Macromolecule Biosynthetic Process MRNA Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Nitrogen Compound Metabolic Process RNA Processing MRNA Processing Cellular Macromolecule Biosynthetic Process Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of Glucose Import In Response To Insulin Stimulus Regulation Of Metabolic Process Positive Regulation Of Gene Expression Metabolic Process Negative Regulation Of Glucose Import Negative Regulation Of Cellular Metabolic Process Cellular Process Negative Regulation Of Gene Expression, Epigenetic Long-chain Fatty Acid Biosynthetic Process Positive Regulation Of Cellular Metabolic Process Negative Regulation Of Glucose Transport Negative Regulation Of Gene Expression Segment Specification Positive Regulation Of Metabolic Process Regulation Of Glucose Import In Response To Insulin Stimulus Regulation Of Glucose Transport Regulation Of RNA Splicing Regulation Of Protein Metabolic Process MRNA Transport Fatty Acid Biosynthetic Process Positive Regulation Of RNA Splicing Palmitic Acid Biosynthetic Process Negative Regulation Of Mitochondrial DNA Replication Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process Maintenance Of ER Location Negative Regulation Of Glucosylceramide Biosynthetic Process
Tagcloud ?		activate cal cancers clarify contribute currently cyclin d1 frequently malignancies mapk mitogen modulating newly occurring occurs oral oscc quaking regulative resulting shows squamous suppressor tumour uncontrolled underexpression unknown world	assembled childhood compatible confirms contiguous definite deletions distinctive dystonia dyt1 eighty gch1 imprinted ireland laxity maternally microcephaly myoclonus nineteen nkx2 phenotypically probable probands progressing sequenced sgce stature uk upper
Tagcloud (Difference) ?		activate cal cancers clarify contribute currently cyclin d1 frequently malignancies mapk mitogen modulating newly occurring occurs oral oscc quaking regulative resulting shows squamous suppressor tumour uncontrolled underexpression unknown world	assembled childhood compatible confirms contiguous definite deletions distinctive dystonia dyt1 eighty gch1 imprinted ireland laxity maternally microcephaly myoclonus nineteen nkx2 phenotypically probable probands progressing sequenced sgce stature uk upper
Tagcloud (Intersection) ?