QKI and RBFOX1

Number of citations of the paper that reports this interaction (PubMedID 16713569)
0

Data Source:
BioGRID (affinity chromatography technology)
HPRD (two hybrid)

		QKI	RBFOX1
Description		QKI, KH domain containing RNA binding	RNA binding fox-1 homolog 1
Image
GO Annotations	Cellular Component	Nucleus Cytoplasm Cytosol Cytoplasmic Stress Granule Synapse	Nucleus Cytoplasm Trans-Golgi Network Cytoplasmic Stress Granule Nuclear Stress Granule
	Molecular Function	Nucleic Acid Binding DNA Binding Transcription Coactivator Activity RNA Binding MRNA Binding MRNA 3'-UTR Binding Protein Binding SH3 Domain Binding MiRNA Binding Internal N(7)-methylguanine-containing RNA Reader Activity	Nucleic Acid Binding RNA Binding MRNA Binding Protein Binding
	Biological Process	Vasculogenesis MRNA Processing Regulation Of Translation Spermatid Development Intracellular MRNA Localization Axon Ensheathment RNA Splicing Positive Regulation Of Gene Expression Regulation Of Epithelial To Mesenchymal Transition Microglia Differentiation Negative Regulation Of Angiogenesis Negative Regulation Of Translation Cell Differentiation Positive Regulation Of Myelination Negative Regulation Of Type I Interferon Production Stress Granule Assembly Vascular Associated Smooth Muscle Cell Differentiation Myelination Long-chain Fatty Acid Biosynthetic Process Positive Regulation Of Cholesterol Biosynthetic Process Regulation Of Macrophage Differentiation Negative Regulation Of Macrophage Differentiation Positive Regulation Of DNA-templated Transcription Regulation Of MRNA Splicing, Via Spliceosome MRNA Stabilization Regulation Of Astrocyte Differentiation Positive Regulation Of Oligodendrocyte Differentiation MRNA Transport Regulation Of Cell Development Negative Regulation Of Cold-induced Thermogenesis Spliceosome-depend Formation Of Circular RNA Negative Regulation Of 3'-UTR-mediated MRNA Stabilization Myofibroblast Contraction Regulation Of Multicellular Organismal Development Negative Regulation Of MiRNA Catabolic Process	Regulation Of Alternative MRNA Splicing, Via Spliceosome MRNA Processing Nervous System Development RNA Splicing Regulation Of RNA Splicing RNA Transport
Pathways		Signaling by BRAF and RAF1 fusions	MECP2 regulates transcription factors
Drugs
Diseases
GWAS		Cataracts ( 34127677) Diastolic blood pressure ( 27841878) Diisocyanate-induced asthma ( 25918132) Fasting insulin ( 34059833) Height ( 31562340) Hemoglobin ( 32888494) Incident myocardial infarction ( 26950853) Mean corpuscular hemoglobin ( 29403010) Mean corpuscular volume ( 29403010) Mosaic loss of chromosome Y (Y chromosome dosage) ( 28346444) Platelet distribution width ( 32888494) Red blood cell count ( 29403010) Refractive error ( 32231278) Response to TNF antagonist treatment ( 18615156) Seasonality and depression ( 30217971) Triglyceride levels ( 32203549) Type 2 diabetes ( 30297969 30718926)	3-month functional outcome in ischaemic stroke (modified Rankin score) ( 30796134) Adult body size ( 32376654) Adverse response to inhaled corticosteroid treatment x age interaction in asthma ( 32119686) Age at first sexual intercourse ( 34211149) Albumin-globulin ratio ( 29403010) Allergic rhinitis ( 25085501) Alzheimer's disease ( 33074286) Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy) ( 31835028) Anxiety ( 33859377) Bitter alcoholic beverage consumption ( 31046077) Bitter non-alcoholic beverage consumption ( 31046077) Body mass index ( 28892062 25673413) Brain glucose metabolism (fluorodeoxyglucose uptake) ( 30596066) Brain volume in infants (cerebrospinal fluid) ( 28763065) Cataracts ( 34127677) Cerebellum white matter volume ( 31530798) Chronotype ( 30696823) Cocaine dependence ( 31212010) Cognitive decline rate in late mild cognitive impairment ( 26252872) Depression ( 33859377 29700475) Evening vs. morning chronotype (sMEQ score) ( 32579418) Extraversion ( 27918536) Feeling worry ( 29500382) Femur bone mineral density x serum urate levels interaction ( 34046847) General cognitive ability ( 29844566) General risk tolerance (MTAG) ( 30643258) Glaucoma ( 25027321) HDL cholesterol levels in HIV infection ( 33109212) High myopia ( 31816047) Hydrolysed wheat protein allergy ( 31301374) Hyperopia ( 25233373) Hypertrophic cardiomyopathy (sarcomere positive) ( 33495597) Insomnia symptoms (never/rarely vs. usually) ( 30804566) Intelligence (MTAG) ( 29326435) Intracranial aneurysm ( 29531279) joint destruction in rheumatoid arthritis (rapid vs slow) ( 33585033) Major depressive disorder ( 29728651 27479909) Mental health study participation (completed survey) ( 31263887) Metabolite levels ( 31628463) Myopia ( 27182965 25233373) Neurociticism ( 29500382) Neurofibrillary tangles ( 31497858) Neuroticism ( 29255261) Nickel levels ( 26025379) Nontraumatic osteonecrosis of the femoral head ( 32701715) Obesity (extreme) ( 31852448) Obesity-related traits ( 23251661) Optic disc size ( 31809533) Photic sneeze reflex ( 27182965) Pit-and-Fissure caries ( 24556642) Refractive astigmatism ( 30306274) Refractive error ( 23396134 32231278 23474815) Renal cell carcinoma ( 31231134) Rheumatoid arthritis ( 30423114) Severe insulin-resistant type 2 diabetes ( 34737425) Spherical equivalent or myopia (age of diagnosis) ( 29808027) Systemising ( 31508503) Systolic blood pressure ( 30224653) Systolic blood pressure and diastolic blood pressure (bivariate analysis) ( 33539483) tricyclic pyrone compound response (IC50) ( 33610756) Triglyceride levels ( 34074324) Type 1 diabetes autoantibodies in high risk HLA genotype individuals (time to event) ( 29310926) Type 2 diabetes ( 30130595) Worry too long after an embarrassing experience ( 29500382)
Interacting Genes		90 interacting genes: ALG13 ANKHD1 APP ATXN1 BAG4 BCAS2 CALD1 CARM1 CCDC59 CCND3 CDKN2D CEBPA CPSF7 DAZ1 DAZ4 DEPP1 DMRTB1 EIF4ENIF1 FBXO7 FHL3 FUBP3 HCLS1 HLCS HNRNPH2 HNRNPK HNRNPLL IL7R KIF21B LSM3 LSM5 MBNL1 MBNL2 MIR141 MIR19B2 MIR200A MIR34B MIR34C MIR7-1 MRPL44 MSI2 NABP1 NEIL3 NIP7 NXF1 PCBP1 PCBP2 PCBP3 PCBP4 PCGF5 PIAS1 PRKAB2 PRMT1 PRPF39 PRPF6 PRRC2B PSMF1 PTBP1 PTBP2 RALY RBFOX1 RBFOX2 RBM11 RBM14 RBM23 RBM42 RBM7 RBPMS RNF138 RPL9 SECISBP2 SERF2 SLAIN1 SNRPA SNRPC TEX11 THAP1 TIAL1 TNRC6A TRNAU1AP TSG101 TXNL4A U2AF2 UNKL USH1C UTP6 WDR77 YTHDF1 YTHDF3 ZC3H10 ZMAT5	49 interacting genes: AGR2 ALG13 ARID5A ATN1 ATXN1 ATXN1L ATXN2 BHLHE40 C1orf94 CELF3 CRX DAB1 DAZAP2 DMRTB1 DVL2 FAM168A GCA HNRNPF HSFX1 HSFY1 HYPK KIFAP3 LASP1 LZTS2 MAGED1 NOC2L NUMBL P4HA3 PCBP4 POGZ PRR20A PRRC2A PSMF1 QKI RBFOX2 RBFOX3 RBM24 RBM47 RBPMS RBPMS2 RHOXF2 SIRPB1 SNRPN SPMIP9 STRBP TNIP1 TOLLIP UBL3 VENTX
Entrez ID		9444	54715
HPRD ID		06691	16091
Ensembl ID		ENSG00000112531	ENSG00000078328
Uniprot IDs		Q8WY44 Q96PU8	A0A6Q8PH77 A0A804HJM2 A0A804HKG7 B7Z1U7 F8VZG9 Q59HD3 Q9NWB1 X5D7T5 X5DNY3 X5DP44
PDB IDs		4JVH	2ERR 2N82 4ZKA 7VRL
Enriched GO Terms of Interacting Partners?		RNA Binding Nucleic Acid Binding Regulation Of RNA Splicing MRNA Binding RNA Splicing Regulation Of MRNA Metabolic Process MRNA Processing MRNA Metabolic Process Nucleic Acid Metabolic Process RNA Processing RNA Metabolic Process Nucleus Regulation Of MRNA Splicing, Via Spliceosome Regulation Of MRNA Processing Nucleobase-containing Compound Metabolic Process Spliceosomal Complex Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process Macromolecule Metabolic Process Ribonucleoprotein Complex Negative Regulation Of MRNA Metabolic Process Post-transcriptional Regulation Of Gene Expression MRNA Splicing, Via Spliceosome Regulation Of Metabolic Process Regulation Of Macromolecule Metabolic Process RNA Splicing, Via Transesterification Reactions Nucleoplasm Negative Regulation Of RNA Splicing Negative Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process MRNA 3'-UTR Binding Cytoplasmic Stress Granule Regulation Of RNA Metabolic Process Negative Regulation Of Metabolic Process U4/U6 X U5 Tri-snRNP Complex Regulation Of Alternative MRNA Splicing, Via Spliceosome Negative Regulation Of MRNA Splicing, Via Spliceosome Negative Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process MiRNA-mediated Post-transcriptional Gene Silencing Negative Regulation Of Biosynthetic Process Negative Regulation Of Gene Expression Regulatory NcRNA-mediated Gene Silencing Regulatory NcRNA-mediated Post-transcriptional Gene Silencing Post-transcriptional Gene Silencing Commitment Complex Regulation Of Translation Viral RNA Genome Replication Regulation Of MRNA Stability Negative Regulation Of RNA Metabolic Process	Regulation Of MRNA Splicing, Via Spliceosome Regulation Of RNA Splicing Regulation Of MRNA Processing Regulation Of Alternative MRNA Splicing, Via Spliceosome Regulation Of MRNA Metabolic Process MRNA Binding RNA Binding Nucleic Acid Binding Regulation Of RNA Metabolic Process Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Primary Metabolic Process Cytoplasmic Stress Granule RNA Splicing Nucleus Regulation Of Macromolecule Metabolic Process Regulation Of Gene Expression Regulation Of Macromolecule Biosynthetic Process MRNA Processing POZ Domain Binding MRNA 3'-UTR Binding MRNA CDS Binding Cytoplasm Regulation Of Metabolic Process Stress Granule Assembly Positive Regulation Of 3'-UTR-mediated MRNA Stabilization Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process RNA Processing Negative Regulation Of MRNA Metabolic Process Regulation Of MRNA Stability Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of RNA Stability MRNA Metabolic Process Pre-mRNA Intronic Binding Positive Regulation Of Macromolecule Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Neurogenesis Positive Regulation Of RNA Metabolic Process Negative Regulation Of RNA Metabolic Process MRNA Stabilization DNA Binding Pre-mRNA Binding Protein Binding Transcription Coactivator Activity Negative Regulation Of MRNA Catabolic Process RNA Stabilization Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Nervous System Development
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