CTNNA1 and CA9

Number of citations of the paper that reports this interaction (PubMedID 14567991)
0

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vitro, in vivo)

		CTNNA1	CA9
Description		catenin alpha 1	carbonic anhydrase 9
Image
GO Annotations	Cellular Component	Acrosomal Vesicle Nucleus Cytoplasm Golgi Apparatus Cytosol Cytoskeleton Plasma Membrane Cell-cell Junction Adherens Junction Zonula Adherens Focal Adhesion Intercalated Disc Actin Cytoskeleton Membrane Catenin Complex Flotillin Complex Lamellipodium Cell Junction Anchoring Junction Plasma Membrane Protein Complex	Nucleus Nucleolus Plasma Membrane Membrane Basolateral Plasma Membrane Microvillus Membrane Cell Projection
	Molecular Function	RNA Binding Structural Molecule Activity Protein Binding Beta-catenin Binding Cytoskeletal Protein Binding Vinculin Binding Identical Protein Binding Protein-containing Complex Binding Gamma-catenin Binding Cadherin Binding Actin Filament Binding	Carbonate Dehydratase Activity Protein Binding Zinc Ion Binding Lyase Activity Metal Ion Binding Molecular Function Activator Activity
	Biological Process	Ovarian Follicle Development Apoptotic Process Cell Adhesion Establishment Or Maintenance Of Cell Polarity Smoothened Signaling Pathway Integrin-mediated Signaling Pathway Neuroblast Proliferation Negative Regulation Of Neuroblast Proliferation Intracellular Protein Localization Male Gonad Development Gap Junction Assembly Cell Migration Axon Regeneration Regulation Of Cell Population Proliferation Odontogenesis Of Dentin-containing Tooth Negative Regulation Of Apoptotic Process Apical Junction Assembly Response To Estrogen Positive Regulation Of Smoothened Signaling Pathway Cell Motility Cellular Response To Indole-3-methanol Epithelial Cell-cell Adhesion Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Cell-cell Adhesion Negative Regulation Of Protein Localization To Nucleus Negative Regulation Of Cell Motility Negative Regulation Of Integrin-mediated Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Response To Hypoxia Morphogenesis Of An Epithelium Response To Xenobiotic Stimulus Response To Testosterone Secretion
Pathways		Adherens junctions interactions VEGFR2 mediated vascular permeability Myogenesis Myogenesis RHO GTPases activate IQGAPs Regulation of CDH11 function Regulation of CDH19 Expression and Function Regulation of CDH1 Function Degradation of CDH1 CDH11 homotypic and heterotypic interactions	Regulation of gene expression by Hypoxia-inducible Factor Reversible hydration of carbon dioxide
Drugs			Benzthiazide Benzthiazide Cyclothiazide Hydroflumethiazide Zonisamide Girentuximab Ellagic acid Sodium carbonate DTP-348
Diseases
GWAS		Femur bone mineral density x serum urate levels interaction ( 34046847) General risk tolerance (MTAG) ( 30643258) Malaria ( 31844061) Schizophrenia ( 25056061)
Interacting Genes		55 interacting genes: ACTN1 AFDN AJUBA AKT1 ALDOB APP ARMC8 BAAT CA9 CCDC180 CDC42 CDH1 CDH15 CDH2 CDH3 CDH5 CSNK2A1 CTBP1 CTNNB1 CTSV DLG1 DYRK1A EIF4ENIF1 F2RL1 FBP1 FBP2 FRAT2 HRAS HSD17B3 HSPA13 JUP LRATD2 MAP2K1 MTNR1A MTNR1B NANS PKD1 PSEN1 RBM26 RNF10 SASH1 SFRP2 SFRP4 SMAD1 SPTAN1 SPTBN1 STX17 TDRD7 TJP1 TJP2 UBE2I VCL ZGPAT ZNF189 ZNF510	6 interacting genes: CAND1 CDH1 CSRP1 CTNNA1 CTNNB1 GLRX3
Entrez ID		1495	768
HPRD ID		00285	04417
Ensembl ID		ENSG00000044115	ENSG00000107159
Uniprot IDs		A0A384MDY0 B4DKT9 B4DU00 G3XAM7 P35221	A0A0S2Z341 A0A0S2Z3D0 Q16790
PDB IDs		1H6G 4EHP 4IGG 6UPV 6V2O 6V2P 7UTJ 9BL2 9BL3 9BL4	2HKF 3IAI 5DVX 5FL4 5FL5 5FL6 6FE0 6FE1 6FE2 6G98 6G9U 6QN2 6QN5 6QN6 6QUT 6RQN 6RQQ 6RQU 6RQW 6TL5 6TL6 6Y74 7POM 8CO0 8Q18 8Q19 8Q1A
Enriched GO Terms of Interacting Partners?		Cell-cell Junction Organization Cell Junction Organization Adherens Junction Cadherin Binding Adherens Junction Organization Cell Junction Assembly Cell-cell Junction Assembly Cell Junction Cell-cell Adhesion Catenin Complex Cell-cell Junction Cell-cell Adhesion Mediated By Cadherin Alpha-catenin Binding Anchoring Junction Cell Adhesion Calcium-dependent Cell-cell Adhesion Via Plasma Membrane Cell Adhesion Molecules Fascia Adherens Anatomical Structure Morphogenesis Regulation Of Cell Motility Regulation Of Protein Localization Glutamatergic Synapse Regulation Of Locomotion Beta-catenin Binding Regulation Of Cell Migration Positive Regulation Of Biosynthetic Process Regulation Of Transcription By RNA Polymerase II Regulation Of Cellular Component Organization Plasma Membrane Cellular Response To Indole-3-methanol Regulation Of Supramolecular Fiber Organization Cell Development Regulation Of Cell Population Proliferation Response To Indole-3-methanol Cytoplasm Cortical Actin Cytoskeleton Negative Regulation Of Nucleobase-containing Compound Metabolic Process Regulation Of Wnt Signaling Pathway Positive Regulation Of Gene Expression Regulation Of DNA-templated Transcription Developmental Process Regulation Of RNA Biosynthetic Process Regulation Of Cell Adhesion Negative Regulation Of Signal Transduction Regulation Of Canonical Wnt Signaling Pathway Regulation Of Multicellular Organismal Development Positive Regulation Of Angiogenesis Positive Regulation Of Macromolecule Biosynthetic Process Protein Kinase Binding Fructose 1,6-bisphosphate Metabolic Process Regulation Of RNA Metabolic Process	Cellular Response To Indole-3-methanol Response To Indole-3-methanol Flotillin Complex Catenin Complex Negative Regulation Of Cell Development Gamma-catenin Binding Cell-cell Junction Assembly Negative Regulation Of Neurogenesis Z Disc Negative Regulation Of Nervous System Development Cell-cell Adhesion Regulation Of Protein Localization To Nucleus Negative Regulation Of Multicellular Organismal Process Cell-cell Junction Organization Regulation Of Protein Sumoylation Adherens Junction Lamellipodium Disordered Domain Specific Binding Cell Junction Apical Junction Complex Negative Regulation Of Cell Differentiation Cell-cell Adhesion Mediated By Cadherin Response To Alcohol Cell Junction Assembly Regulation Of Neuroblast Proliferation Neuroblast Proliferation Intercalated Disc Regulation Of Cell Development Cadherin Binding Cell Adhesion Adherens Junction Organization Cellular Response To Oxygen-containing Compound Apoptotic Signaling Pathway Regulation Of Protein Localization Negative Regulation Of Developmental Process Lateral Plasma Membrane Regulation Of Neurogenesis Odontogenesis Of Dentin-containing Tooth Ligase Inhibitor Activity Glial Cell Fate Determination Canonical Wnt Signaling Pathway Involved In Mesenchymal Stem Cell Differentiation Anchoring Junction Focal Adhesion Regulation Of Nervous System Development Negative Regulation Of Post-translational Protein Modification Beta-catenin Binding Regulation Of Cell-cell Adhesion Positive Regulation Of Protein Localization To Nucleus Cell Junction Organization Epidermal Cell Differentiation
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