CTNNA1 and CDH3

Number of citations of the paper that reports this interaction (PMID 1924379)
83

Data Source:
HPRD (in vivo)

		CTNNA1	CDH3
Gene Name		catenin (cadherin-associated protein), alpha 1, 102kDa	cadherin 3, type 1, P-cadherin (placental)
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Acrosomal Vesicle Cytosol Plasma Membrane Cell-cell Junction Zonula Adherens Focal Adhesion Intercalated Disc Actin Cytoskeleton Catenin Complex Lamellipodium	Cytoplasm Plasma Membrane Cell-cell Adherens Junction Integral Component Of Membrane
	Molecular Function	Structural Molecule Activity Protein Binding Beta-catenin Binding Vinculin Binding Poly(A) RNA Binding Gamma-catenin Binding Cadherin Binding Actin Filament Binding	Molecular_function Calcium Ion Binding
	Biological Process	Ovarian Follicle Development Actin Filament Organization Cell Adhesion Establishment Or Maintenance Of Cell Polarity Negative Regulation Of Neuroblast Proliferation Aging Male Gonad Development Gap Junction Assembly Axon Regeneration Cell Junction Assembly Adherens Junction Organization Cellular Protein Localization Odontogenesis Of Dentin-containing Tooth Muscle Cell Differentiation Apical Junction Assembly Response To Estrogen Cell-cell Junction Organization Positive Regulation Of Smoothened Signaling Pathway Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Muscle Cell Differentiation Protein Heterooligomerization Cellular Response To Indole-3-methanol Epithelial Cell-cell Adhesion Negative Regulation Of Cell Motility Negative Regulation Of Integrin-mediated Signaling Pathway Negative Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand Positive Regulation Of Extrinsic Apoptotic Signaling Pathway In Absence Of Ligand	Retina Homeostasis Cell Adhesion Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Visual Perception Positive Regulation Of Gene Expression Positive Regulation Of Keratinocyte Proliferation Single Organismal Cell-cell Adhesion Hair Cycle Process Keratinization Positive Regulation Of Monophenol Monooxygenase Activity Negative Regulation Of Transforming Growth Factor Beta2 Production Cell Junction Assembly Adherens Junction Organization Wound Healing Response To Drug Positive Regulation Of Insulin-like Growth Factor Receptor Signaling Pathway Cell-cell Junction Organization Positive Regulation Of Melanin Biosynthetic Process Negative Regulation Of Catagen Canonical Wnt Signaling Pathway Regulation Of Hair Cycle By Canonical Wnt Signaling Pathway Positive Regulation Of Melanosome Transport
Pathways		Cell junction organization Cell-cell junction organization CDO in myogenesis Myogenesis Signaling by VEGF Adherens junctions interactions VEGFR2 mediated vascular permeability VEGFA-VEGFR2 Pathway	Cell junction organization Cell-cell junction organization Adherens junctions interactions
Drugs
Diseases
GWAS
Protein-Protein Interactions		27 interactors: ACTN1 AJUBA APC APP ARMC8 CA9 CDH1 CDH15 CDH2 CDH3 CDH5 CTBP1 CTNNB1 DLG1 FAM84B JUP MLLT4 PKD1 PSEN1 RNF219 SPTAN1 SPTBN1 SUMO1 TJP1 TJP2 VCL ZGPAT	3 interactors: CTNNA1 CTNNB1 CTNND1
Entrez ID		1495	1001
HPRD ID		00285	00227
Ensembl ID		ENSG00000044115	ENSG00000062038
Uniprot IDs		P35221	J3KTE9 P22223
PDB IDs		1H6G 4EHP 4IGG
Enriched GO Terms of Interacting Partners?		Cell Junction Assembly Cell-cell Junction Organization Adherens Junction Organization Cell Adhesion Cellular Component Assembly Epithelium Development Developmental Process Anatomical Structure Development Cell-cell Junction Assembly Cellular Component Disassembly Involved In Execution Phase Of Apoptosis Single Organismal Cell-cell Adhesion Execution Phase Of Apoptosis Adherens Junction Assembly Cell Differentiation Tissue Development Cell-cell Adhesion Via Plasma-membrane Adhesion Molecules Cell-cell Adhesion Cell Development Cellular Response To Indole-3-methanol Establishment Of Endothelial Barrier Apical Junction Assembly Anatomical Structure Morphogenesis Establishment Of Endothelial Intestinal Barrier Regulation Of Protein Complex Assembly Regulation Of Cellular Process Homophilic Cell Adhesion Via Plasma Membrane Adhesion Molecules Skin Development Regulation Of Signal Transduction Movement Of Cell Or Subcellular Component Endothelial Cell Development Tight Junction Assembly Positive Regulation Of Protein Metabolic Process Locomotion Endomembrane System Organization Neurogenesis Apoptotic Process Regulation Of Epithelial Cell Proliferation Regulation Of Signaling Cell Morphogenesis Involved In Differentiation Programmed Cell Death Morphogenesis Of An Epithelium Cell Death Death Cell-matrix Adhesion Positive Regulation Of Protein Complex Assembly Positive Regulation Of Cellular Protein Metabolic Process Endothelial Cell Differentiation Neuron Differentiation Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Protein Localization	Adherens Junction Organization Cellular Response To Indole-3-methanol Cell Junction Assembly Cell-cell Junction Organization Regulation Of Neuroblast Proliferation Single Organismal Cell-cell Adhesion Positive Regulation Of Muscle Cell Differentiation Odontogenesis Of Dentin-containing Tooth Regulation Of Neural Precursor Cell Proliferation Regulation Of Stem Cell Proliferation Vascular Endothelial Growth Factor Receptor Signaling Pathway Odontogenesis Protein Heterooligomerization Negative Regulation Of Signal Transduction Negative Regulation Of Signaling Cell Adhesion Regulation Of Muscle Cell Differentiation Male Sex Differentiation Response To Estrogen Negative Regulation Of Mitotic Cell Cycle, Embryonic Positive Regulation Of Epithelial Cell Proliferation Involved In Prostate Gland Development Negative Regulation Of Integrin-mediated Signaling Pathway Schwann Cell Proliferation Cellular Response To Insulin-like Growth Factor Stimulus Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Regulation Of Canonical Wnt Signaling Pathway Negative Regulation Of Apoptotic Signaling Pathway Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Cardiac Outflow Tract Cell Proliferation Renal Inner Medulla Development Renal Outer Medulla Development Mesenchymal Cell Proliferation Involved In Lung Development Glial Cell Fate Determination Oviduct Development Regulation Of Centriole-centriole Cohesion Negative Regulation Of Neurogenesis Wnt Signaling Pathway Sex Differentiation Positive Regulation Of Determination Of Dorsal Identity Lung Induction Embryonic Skeletal Limb Joint Morphogenesis Canonical Wnt Signaling Pathway Involved In Regulation Of Cell Proliferation Regulation Of Wnt Signaling Pathway Negative Regulation Of Cell Development Cellular Component Assembly Muscle Cell Differentiation Central Nervous System Vasculogenesis Trachea Formation Regulation Of Centromeric Sister Chromatid Cohesion Renal Vesicle Formation
Tagcloud ?		alphae alphat cardiomyocyte cardiomyocytes catenin catenins coactivator contractility cre delete divide dying gained heart hearts injured knockout lose perinatal proof rationale regulators replace shortly transgenes unable yap yes	blastocysts bts cdx2 chir99021 continually cyp11a1 dome elf5 eomes ets2 feeders gcm1 gdf3 hand1 hsd17b1 mash2 nanog oct4 pd0325901 pparg smarca4 sox2 ssea tdk tead4 teratomas tfap2a thap11 tscs
Tagcloud (Difference) ?		alphae alphat cardiomyocyte cardiomyocytes catenin catenins coactivator contractility cre delete divide dying gained heart hearts injured knockout lose perinatal proof rationale regulators replace shortly transgenes unable yap yes	blastocysts bts cdx2 chir99021 continually cyp11a1 dome elf5 eomes ets2 feeders gcm1 gdf3 hand1 hsd17b1 mash2 nanog oct4 pd0325901 pparg smarca4 sox2 ssea tdk tead4 teratomas tfap2a thap11 tscs
Tagcloud (Intersection) ?