GRHPR and LSM1

Number of citations of the paper that reports this interaction (PMID 15231747)
44

Data Source:
HPRD (two hybrid)

		GRHPR	LSM1
Gene Name		glyoxylate reductase/hydroxypyruvate reductase	LSM1, U6 small nuclear RNA associated
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Peroxisomal Matrix Cytosol Extracellular Vesicular Exosome	Cytoplasmic MRNA Processing Body Nucleus Cytoplasm Cytosol
	Molecular Function	Glycerate Dehydrogenase Activity Hydroxypyruvate Reductase Activity Glyoxylate Reductase (NADP) Activity Carboxylic Acid Binding Protein Homodimerization Activity NAD Binding NADPH Binding	RNA Cap Binding Protein Binding Poly(A) RNA Binding
	Biological Process	Excretion Metabolic Process Cellular Nitrogen Compound Metabolic Process Dicarboxylic Acid Metabolic Process Small Molecule Metabolic Process Glyoxylate Metabolic Process Protein Oligomerization Oxidation-reduction Process	Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA RNA Splicing, Via Transesterification Reactions MRNA Processing RNA Splicing Gene Expression Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Histone MRNA Catabolic Process
Pathways		Glyoxylate metabolism Metabolism of amino acids and derivatives	mRNA decay by 5' to 3' exoribonuclease Deadenylation-dependent mRNA decay
Drugs
Diseases
GWAS			Schizophrenia ( 22037555)
Protein-Protein Interactions		6 interactors: CDC7 FOS GLS2 LIG4 LSM1 PTH2R	25 interactors: CLIC1 EXOSC6 EXOSC8 GLUD1 GRHPR HSP90AA1 LSM2 LSM3 LSM4 LSM5 LSM6 LSM7 MPDU1 N4BP1 NARS NDUFAF3 PSMB5 PSMB8 PTPRC RRP1B SMN1 TMEM214 UPF2 UXT VPS11
Entrez ID		9380	27257
HPRD ID		05052	06281
Ensembl ID		ENSG00000137106	ENSG00000175324
Uniprot IDs		Q9UBQ7	O15116
PDB IDs		2GCG 2H1S 2Q50 2WWR
Enriched GO Terms of Interacting Partners?		DNA Ligation Involved In DNA Recombination DNA-dependent DNA Replication Cellular Response To Metal Ion Double-strand Break Repair Via Break-induced Replication Cellular Response To Inorganic Substance Double-strand Break Repair Positive Regulation Of Nuclear Cell Cycle DNA Replication Lagging Strand Elongation Pro-B Cell Differentiation Conditioned Taste Aversion DNA Recombination DNA Metabolic Process Establishment Of Integrated Proviral Latency DNA Replication Deadenylation-dependent Decapping Of Nuclear-transcribed MRNA Cellular Nitrogen Compound Metabolic Process Immunoglobulin V(D)J Recombination Establishment Of Viral Latency Histone MRNA Catabolic Process T Cell Receptor V(D)J Recombination Regulation Of Nuclear Cell Cycle DNA Replication DNA Ligation Involved In DNA Repair Response To Metal Ion Lymphoid Progenitor Cell Differentiation Nitrogen Compound Metabolic Process DNA Ligation Sleep Response To Gravity Positive Regulation Of DNA-dependent DNA Replication Nucleotide-excision Repair, DNA Gap Filling Cellular Response To Lithium Ion Cellular Response To Stress Cell Division Response To Radiation Histone MRNA Metabolic Process Response To Inorganic Substance Single Strand Break Repair Double-strand Break Repair Via Nonhomologous End Joining Response To Immobilization Stress Glutamate Secretion Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Positive Regulation Of Osteoclast Differentiation Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Isotype Switching	Exonucleolytic Nuclear-transcribed MRNA Catabolic Process Involved In Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process, Exonucleolytic Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Nuclear-transcribed MRNA Catabolic Process MRNA Catabolic Process RNA Catabolic Process MRNA Metabolic Process Cellular Macromolecule Catabolic Process Aromatic Compound Catabolic Process RNA Splicing Catabolic Process MRNA Processing Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process RNA Processing Gene Expression RNA Metabolic Process NcRNA Metabolic Process RRNA Processing RRNA Metabolic Process Ribonucleoprotein Complex Biogenesis Ribosome Biogenesis MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Cellular Metabolic Process Cell Cycle Phase Transition Negative Regulation Of Protein Ubiquitination Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Protein Ubiquitination Negative Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Ligase Activity Involved In Regulation Of Mitotic Cell Cycle Transition Signal Transduction Involved In DNA Damage Checkpoint Signal Transduction Involved In Cell Cycle Checkpoint Immunoglobulin Production Regulation Of Ubiquitin-protein Ligase Activity Involved In Mitotic Cell Cycle Negative Regulation Of Ubiquitin-protein Transferase Activity Immunoglobulin Biosynthetic Process Positive Regulation Of Hematopoietic Stem Cell Migration Mitotic Cell Cycle Phase Transition Anaphase-promoting Complex-dependent Proteasomal Ubiquitin-dependent Protein Catabolic Process Mitotic G1 DNA Damage Checkpoint Positive Regulation Of Ubiquitin-protein Transferase Activity Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Positive Regulation Of Cell Cycle Arrest Positive Regulation Of Ligase Activity
Tagcloud ?			activators cerevisiae codons dcp1 dcp2 deadenylation decapping decay defines dhh1 edc1 edc2 edc3 hybrid nmd nonsense overlapping pat1 premature proper recruit saccharomyces stimulators termed termination transcripts upf1 upf2 upf3
Tagcloud (Difference) ?			activators cerevisiae codons dcp1 dcp2 deadenylation decapping decay defines dhh1 edc1 edc2 edc3 hybrid nmd nonsense overlapping pat1 premature proper recruit saccharomyces stimulators termed termination transcripts upf1 upf2 upf3
Tagcloud (Intersection) ?