ALOX5 and SYCE1

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		ALOX5	SYCE1
Gene Name		arachidonate 5-lipoxygenase	synaptonemal complex central element protein 1
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Nuclear Envelope Nuclear Envelope Lumen Cytosol Nuclear Matrix Nuclear Membrane	Central Element
	Molecular Function	Arachidonate 5-lipoxygenase Activity Iron Ion Binding Protein Binding
	Biological Process	Leukotriene Production Involved In Inflammatory Response Leukotriene Metabolic Process Arachidonic Acid Metabolic Process Leukotriene Biosynthetic Process Lipoxygenase Pathway Small Molecule Metabolic Process Oxidation-reduction Process Lipoxin Metabolic Process	Synaptonemal Complex Assembly Cell Division
Pathways		Arachidonic acid metabolism Synthesis of 5-eicosatetraenoic acids Metabolism of lipids and lipoproteins Synthesis of Lipoxins (LX) Synthesis of Leukotrienes (LT) and Eoxins (EX)	Meiotic synapsis
Drugs		Vitamin E Masoprocol Aminosalicylic Acid Mesalazine Montelukast Diclofenac Diethylcarbamazine Zileuton Sulfasalazine Meclofenamic acid Balsalazide Minocycline Hyperforin Heme
Diseases
GWAS		Mean corpuscular hemoglobin ( 20139978) Mean corpuscular volume ( 20139978)
Protein-Protein Interactions		17 interactors: ACTB ALOX5AP APP CEP57L1 CEP63 COTL1 DICER1 GRB2 HHIPL2 LTC4S MAD1L1 MAPKAPK2 MEOX1 NUTM1 REL SYCE1 TGFBRAP1	29 interactors: ALOX5 ARNT2 BFSP2 CCDC102B CCDC53 CINP CYTH3 EDRF1 FAM161A HAUS1 HMG20B HOOK1 HSPB7 IQUB KIFC3 MRFAP1L1 NME7 RBCK1 SCNM1 SKA1 SMARCE1 SPERT SSX2 STX19 TPM1 TPM3 TRAF1 TSG101 ZNF124
Entrez ID		240	93426
HPRD ID		01065	12598
Ensembl ID		ENSG00000012779	ENSG00000171772
Uniprot IDs		E5FPY5 E5FPY8 P09917	Q8N0S2
PDB IDs		2ABV 3O8Y 3V92 3V98 3V99
Enriched GO Terms of Interacting Partners?		Leukotriene Metabolic Process Lipoxin Metabolic Process Arachidonic Acid Metabolic Process Defense Response Lipoxygenase Pathway Icosanoid Metabolic Process Unsaturated Fatty Acid Metabolic Process Long-chain Fatty Acid Metabolic Process Leukotriene Biosynthetic Process Cellular Component Assembly MRNA Stabilization Innate Immune Response Cell Division Immune System Process Platelet Activation Cell Cycle Process Cell Cycle Checkpoint Icosanoid Biosynthetic Process Wound Healing Regulation Of MRNA Stability Unsaturated Fatty Acid Biosynthetic Process Regulation Of RNA Stability Neuron Projection Morphogenesis Conversion Of Ds SiRNA To Ss SiRNA Involved In RNA Interference Regulation Of Metaphase Plate Congression Hair Follicle Cell Proliferation Conversion Of Ds SiRNA To Ss SiRNA Positive Regulation Of Metabolic Process Response To External Stimulus Endocytosis Response To Stress Response To Wounding Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Fatty Acid Metabolic Process Immune Response Microtubule-based Process Regulation Of ERBB Signaling Pathway Regulation Of Enamel Mineralization Peripheral Nervous System Myelin Formation Synaptic Growth At Neuromuscular Junction Zygote Asymmetric Cell Division Spindle Assembly Cell Cycle Neuron Projection Development Signal Transduction In Response To DNA Damage Cell Projection Morphogenesis Vesicle-mediated Transport Targeting Of MRNA For Destruction Involved In RNA Interference Collateral Sprouting In Absence Of Injury Axon Guidance	Organelle Organization Actin-myosin Filament Sliding Muscle Filament Sliding Visual Perception Sensory Perception Of Light Stimulus Cell Division Actin-mediated Cell Contraction Leukotriene Production Involved In Inflammatory Response Positive Regulation Of Heart Rate By Epinephrine
Tagcloud ?		af4 calcitriol conversely deacetylase derivatives deriving elongation encodes hdac hdac1 hdaci inactive lineage lipoxygenase mll overwrites physiologically portion relieving smad3 smad4 surprisingly switch transcriptionally transforming trichostatin trimethylation tsa	adenocarcinoma adenocarcinomas antigens applications broadens carcinomas complementary concordant ct distinctly expressed family il13ra2 immunotherapeutic lung member members nontumor particular searched spectrum squamous subset testes testis vcx vcx3a xage1
Tagcloud (Difference) ?		af4 calcitriol conversely deacetylase derivatives deriving elongation encodes hdac hdac1 hdaci inactive lineage lipoxygenase mll overwrites physiologically portion relieving smad3 smad4 surprisingly switch transcriptionally transforming trichostatin trimethylation tsa	adenocarcinoma adenocarcinomas antigens applications broadens carcinomas complementary concordant ct distinctly expressed family il13ra2 immunotherapeutic lung member members nontumor particular searched spectrum squamous subset testes testis vcx vcx3a xage1
Tagcloud (Intersection) ?