CD163 and MYH9

Number of citations of the paper that reports this interaction (PMID 15479433)
1

Data Source:
HPRD (in vivo)

		CD163	MYH9
Gene Name		CD163 molecule	myosin, heavy chain 9, non-muscle
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Region Plasma Membrane Integral Component Of Plasma Membrane Endocytic Vesicle Membrane	Stress Fiber Ruffle Immunological Synapse Uropod Nucleus Cytoplasm Spindle Actomyosin Contractile Ring Cytosol Plasma Membrane Cell-cell Adherens Junction COP9 Signalosome Integrin Complex Actin Cytoskeleton Membrane Myosin II Complex Cortical Cytoskeleton Cell Leading Edge Neuromuscular Junction Cleavage Furrow Actomyosin Protein Complex Extracellular Vesicular Exosome Myosin II Filament
	Molecular Function	Scavenger Receptor Activity Protein Binding	Microfilament Motor Activity Motor Activity Actin Binding Protein Binding Calmodulin Binding ATP Binding ATPase Activity Actin-dependent ATPase Activity Protein Homodimerization Activity Protein Anchor ADP Binding Poly(A) RNA Binding Actin Filament Binding
	Biological Process	Receptor-mediated Endocytosis Acute-phase Response	Meiotic Spindle Organization Cytokinesis Angiogenesis In Utero Embryonic Development Establishment Of T Cell Polarity Membrane Protein Ectodomain Proteolysis Integrin-mediated Signaling Pathway Axon Guidance Myoblast Fusion Regulation Of Cell Shape Protein Transport Actin Filament-based Movement Platelet Formation Monocyte Differentiation Actomyosin Structure Organization Actin Cytoskeleton Reorganization Uropod Organization Termination Of G-protein Coupled Receptor Signaling Pathway Blood Vessel Endothelial Cell Migration Ephrin Receptor Signaling Pathway Leukocyte Migration Establishment Of Meiotic Spindle Localization Platelet Aggregation
Pathways		Scavenging of heme from plasma	EPHA-mediated growth cone collapse Axon guidance Semaphorin interactions EPH-Ephrin signaling Sema4D in semaphorin signaling Fcgamma receptor (FCGR) dependent phagocytosis Regulation of actin dynamics for phagocytic cup formation Sema4D induced cell migration and growth-cone collapse Innate Immune System
Drugs
Diseases
GWAS		Hematological and biochemical traits ( 20139978)	End-stage renal disease (non-diabetic) ( 20532800) Glomerulosclerosis ( 20668430) Optic disc size (rim) ( 20395239)
Protein-Protein Interactions		4 interactors: CSNK2B HP MYH9 PRKCA	22 interactors: ASCC2 CASP4 CBL CD163 CSNK2A1 CXCR4 GRB2 GRIN1 MEN1 MYBPC3 MYH10 MYL9 MYOM1 MYOM2 OVGP1 PPP2CA PTPN6 RAC1 S100A4 TTN TUFM YWHAZ
Entrez ID		9332	4627
HPRD ID		05708	01177
Ensembl ID		ENSG00000177575	ENSG00000100345
Uniprot IDs		C9JHR8 Q86VB7	P35579
PDB IDs			2LNK 3ZWH 4ETO
Enriched GO Terms of Interacting Partners?		Regulation Of Blood Vessel Endothelial Cell Migration Response To External Stimulus Chemotaxis Regulation Of Endothelial Cell Migration Negative Regulation Of Hydrogen Peroxide Catabolic Process Positive Regulation Of Dense Core Granule Biogenesis Regulation Of Epithelial Cell Migration Histone H3-T6 Phosphorylation Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Platelet Activation Leukocyte Migration Locomotion Negative Regulation Of Hydrogen Peroxide Metabolic Process Cell Cycle Uropod Organization Establishment Of Meiotic Spindle Localization Establishment Of T Cell Polarity Movement Of Cell Or Subcellular Component Peptidyl-serine Autophosphorylation Positive Regulation Of Lipopolysaccharide-mediated Signaling Pathway Angiogenesis Positive Regulation Of Activin Receptor Signaling Pathway Adiponectin-activated Signaling Pathway Desmosome Assembly Negative Regulation Of Glial Cell Apoptotic Process Axon Guidance Regulation Of Hydrogen Peroxide Metabolic Process Endothelial Tube Morphogenesis Negative Regulation Of Glucose Import Blood Coagulation Blood Vessel Morphogenesis Hemostasis Positive Regulation Of Macrophage Differentiation Meiotic Spindle Organization Desmosome Organization Blood Vessel Development Regulation Of Platelet Aggregation Negative Regulation Of Glucose Transport Immune System Process Axonogenesis Induction Of Positive Chemotaxis Positive Regulation Of Cardiac Muscle Hypertrophy Vasculature Development Protein Metabolic Process Monocyte Differentiation Membrane Protein Ectodomain Proteolysis Negative Regulation Of Blood Vessel Endothelial Cell Migration Positive Regulation Of Blood Vessel Endothelial Cell Migration Regulation Of Lipopolysaccharide-mediated Signaling Pathway Axon Development	Cell Morphogenesis Involved In Differentiation Cell Development Platelet Activation Axon Guidance Enzyme Linked Receptor Protein Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Cell Morphogenesis Movement Of Cell Or Subcellular Component Anatomical Structure Morphogenesis Axonogenesis Axon Development Cell Morphogenesis Involved In Neuron Differentiation Wound Healing Chemotaxis Locomotion Positive Regulation Of Signal Transduction Neuron Projection Morphogenesis Apoptotic Process Muscle Contraction Cell Activation Blood Coagulation Programmed Cell Death Hemostasis Ephrin Receptor Signaling Pathway Response To Wounding Cell Death Death Muscle System Process Neuron Projection Development Cell Projection Morphogenesis Myosin Filament Assembly Cell Part Morphogenesis Regulation Of Body Fluid Levels Cell Differentiation Neuron Development Regulation Of Cellular Component Organization Actin Filament-based Movement Regulation Of Signaling Cell Surface Receptor Signaling Pathway Endomembrane System Organization Neuron Differentiation T Cell Costimulation Myofibril Assembly Leukocyte Migration Brain Development Cell Projection Organization Regulation Of Kinase Activity Head Development Regulation Of Signal Transduction Anatomical Structure Development
Tagcloud ?		27cm3 39cm3 alternatively capacities ccl22 considering correlate cultivation documented emt hazard hcc hepatocellular infiltration injuries invasiveness m2 macrophage macrophages mesenchymal mhcc97l nodules orthotopic proven quantified scavenger snail tumour venous	abundance acetylation attempt capability cognate consolidate coordinating cytoplasmic deacetylase deacetylation diversity dnaj dnaja1 elucidated hdac6 homolog hsc70 knockout modulates monitor myosin negatively notion participates predominantly proteomic serves subfamily verified
Tagcloud (Difference) ?		27cm3 39cm3 alternatively capacities ccl22 considering correlate cultivation documented emt hazard hcc hepatocellular infiltration injuries invasiveness m2 macrophage macrophages mesenchymal mhcc97l nodules orthotopic proven quantified scavenger snail tumour venous	abundance acetylation attempt capability cognate consolidate coordinating cytoplasmic deacetylase deacetylation diversity dnaj dnaja1 elucidated hdac6 homolog hsc70 knockout modulates monitor myosin negatively notion participates predominantly proteomic serves subfamily verified
Tagcloud (Intersection) ?