CD163

Description		CD163 molecule
Image
GO Annotations	Cellular Component	Extracellular Region Cytoplasm Cytosol Plasma Membrane External Side Of Plasma Membrane Membrane Endocytic Vesicle Membrane
	Molecular Function	Scavenger Receptor Activity Protein Binding Scaffold Protein Binding
	Biological Process	Acute-phase Response Inflammatory Response Vesicle-mediated Transport
Pathways		Scavenging of heme from plasma CD163 mediating an anti-inflammatory response
Drugs		Tetrachlorodecaoxide
Diseases
GWAS		Creatine kinase levels ( 29403010) HDL cholesterol levels ( 28334899) Hematological and biochemical traits ( 20139978) High density lipoprotein cholesterol levels ( 29083408)
Novel Interacting Genes		1 novel interacting genes: ERC1
Interacting Genes		6 interacting genes: CSNK2B FCGR1A HOXA1 HP MYH9 PRKCA
Entrez ID		9332
HPRD ID		05708
Ensembl ID		ENSG00000177575
Uniprot IDs		C9JHR8 Q86VB7
PDB IDs		8XMK 8XMP 8XMQ 8XMW 9FHB 9FMU 9FNO
Enriched GO Terms of Interacting Partners?		Phosphorylation Protein Kinase CK2 Complex Protein Phosphorylation Symbiont-mediated Disruption Of Host Cell PML Body Regulation Of Metabolic Process Regulation Of Blood Vessel Endothelial Cell Migration Phagocytosis, Engulfment Membrane Invagination High-affinity IgG Receptor Activity Acute Inflammatory Response Positive Regulation Of Type III Hypersensitivity Semicircular Canal Formation Abducens Nerve Formation Optokinetic Behavior Negative Regulation Of Hydrogen Peroxide Catabolic Process Uropod Organization Myosin II Filament Cortical Granule Exocytosis Negative Regulation Of Actin Filament Severing Positive Regulation Of Protein Processing In Phagocytic Vesicle Calcium,diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of Dense Core Granule Biogenesis Positive Regulation Of Angiotensin-activated Signaling Pathway Histone H3T6 Kinase Activity Alphav-beta3 Integrin-PKCalpha Complex I-kappaB Phosphorylation Anatomical Structure Morphogenesis Positive Regulation Of Type IIa Hypersensitivity Integrin Binding Actomyosin Contractile Ring Protein Kinase C Signaling Membrane Organization Release From Viral Latency Hemoglobin Binding Response To Reactive Oxygen Species Cortical Granule Cytoplasmic Actin-based Contraction Involved In Cell Motility Regulation Of Angiotensin-activated Signaling Pathway Protein Metabolic Process Positive Regulation Of Activin Receptor Signaling Pathway Negative Regulation Of Viral Life Cycle IgG Receptor Activity Negative Regulation Of Hydrogen Peroxide Metabolic Process Positive Regulation Of Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Endothelial Cell Migration Adiponectin-activated Signaling Pathway Positive Regulation Of Hypersensitivity Positive Regulation Of Acute Inflammatory Response To Antigenic Stimulus Antibody-dependent Cellular Cytotoxicity Anatomical Structure Formation Involved In Morphogenesis
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