GTF3C5 and TBP

Number of citations of the paper that reports this interaction (PMID 10373544)
23

Data Source:
BioGRID (pull down)

		GTF3C5	TBP
Gene Name		general transcription factor IIIC, polypeptide 5, 63kDa	TATA box binding protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Factor TFIIIC Complex Nucleoplasm	Female Pronucleus Male Pronucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIA Complex Nuclear Euchromatin Cytoplasm
	Molecular Function	DNA Binding Protein Binding	RNA Polymerase II Repressing Transcription Factor Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Transcription Regulatory Region DNA Binding Repressing Transcription Factor Binding
	Biological Process	Transcription, DNA-templated Transcription From RNA Polymerase III Promoter Gene Expression Skeletal Muscle Cell Differentiation 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter	Chromatin Silencing At RDNA Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Transcription From RNA Polymerase III Promoter Spermatogenesis Gene Expression Viral Process Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription, DNA-templated
Pathways		RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 2 Promoter	RNA Polymerase II Promoter Escape RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase I Chain Elongation RNA Polymerase II Transcription RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Clearance HIV Infection RNA Polymerase II Pre-transcription Events HIV Life Cycle HIV Transcription Initiation NoRC negatively regulates rRNA expression RNA Polymerase II HIV Promoter Escape RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I Transcription RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Escape Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression Late Phase of HIV Life Cycle RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase II Transcription Initiation SIRT1 negatively regulates rRNA Expression Transcription of the HIV genome
Drugs
Diseases
GWAS			Type 1 diabetes ( 21980299)
Protein-Protein Interactions		12 interactors: BRF1 GTF3C3 GTF3C4 GTF3C6 KRT40 KRTAP10-3 MDFI NOTCH2NL SRA1 TBP TCF21 TCF4	113 interactors: ABT1 AHR AR ATF4 BCL3 BRD2 BRF1 BRF2 BTAF1 CAND2 CITED2 COL26A1 CREG1 CREM CTBP1 CTD CXXC1 DHX9 DR1 DRAP1 E2F1 EDF1 ELF3 ESR1 FATE1 FOS FOXF2 GOLGA2 GTF2A1 GTF2A1L GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H4 GTF3C2 GTF3C3 GTF3C4 GTF3C5 HAP1 HIST3H3 HMGB1 HNF4A HNRNPK HSF1 HTT IKZF1 JUN JUND KDM5A KLF5 MCM2 MDM2 MSX1 MYC NACA NCOA1 NCOA3 NCOA6 NFYB NFYC NR3C1 PAX3 PAX5 PAX6 PIAS1 PIAS3 POLR2A POLR3F POU2F1 POU2F2 POU3F2 PSMC2 RB1 REL RELA REST RNF4 RUVBL1 RUVBL2 RXRA SNAPC1 SNAPC2 SNAPC4 SP1 SPI1 SPIB SSX2IP SUB1 TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1A TAF1B TAF1C TAF1L TAF5 TAF7L TCF12 TEAD1 TP53 TRAM2 TRIP4 UBE2I UBTF WDR62 YWHAE ZNF76
Entrez ID		9328	6908
HPRD ID		16077	02511
Ensembl ID		ENSG00000148308	ENSG00000112592
Uniprot IDs		H9KV68 Q9Y5Q8	P20226 Q32MN6 Q32MN7
PDB IDs			1C9B 1CDW 1JFI 1NVP 1TGH
Enriched GO Terms of Interacting Partners?		TRNA Transcription Transcription From RNA Polymerase III Promoter RRNA Transcription 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter Transcription, DNA-templated RNA Biosynthetic Process DNA-templated Transcription, Initiation RNA Metabolic Process Transcription Initiation From RNA Polymerase III Promoter Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Embryonic Organ Development Reproductive Structure Development Reproductive System Development Embryonic Digestive Tract Morphogenesis Nucleobase-containing Compound Metabolic Process Single Organism Reproductive Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Embryonic Morphogenesis Reproductive Process Cellular Nitrogen Compound Metabolic Process Embryonic Digestive Tract Development Developmental Process Involved In Reproduction Nitrogen Compound Metabolic Process Embryonic Organ Morphogenesis Transcription From RNA Polymerase II Promoter Digestive Tract Morphogenesis Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus Embryo Development Multicellular Organism Growth Embryonic Placenta Development Cell Differentiation Blood Vessel Development Vasculature Development Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Proepicardium Development Negative Regulation Of Gene Expression Digestive Tract Development Negative Regulation Of Biosynthetic Process Maintenance Of DNA Repeat Elements Bronchiole Development Digestive System Development	Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Aromatic Compound Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Biosynthetic Process Regulation Of Gene Expression Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process DNA-templated Transcription, Initiation Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Cellular Metabolic Process Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Viral Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Regulation Of Cellular Process Metabolic Process Chromosome Organization Chromatin Organization Chromatin Modification Transcription From RNA Polymerase III Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Peptidyl-lysine Modification Histone Acetylation Internal Peptidyl-lysine Acetylation
Tagcloud ?		acetylated allowing architecture became branching chipseq coordinated depolarization depolarizing discovered dramatic factories interplay interspersed mimicked nee rearrangement relies relocated relocation remarkably silencing sines somatosensory synaptic tfiiic tfs timely uncontrolled	60s analyzing cerevisiae codons defect efficiently encodes facilitates fflux firefly gfp homologue hsp70 inducible modest mutant polysome polysomes rarely saccharomyces strain surprisingly tata translated translation turnover ydj1 ydj1p yeast
Tagcloud (Difference) ?		acetylated allowing architecture became branching chipseq coordinated depolarization depolarizing discovered dramatic factories interplay interspersed mimicked nee rearrangement relies relocated relocation remarkably silencing sines somatosensory synaptic tfiiic tfs timely uncontrolled	60s analyzing cerevisiae codons defect efficiently encodes facilitates fflux firefly gfp homologue hsp70 inducible modest mutant polysome polysomes rarely saccharomyces strain surprisingly tata translated translation turnover ydj1 ydj1p yeast
Tagcloud (Intersection) ?