TBP and TAF7L

Number of citations of the paper that reports this interaction (PMID 12665565)
29

Data Source:
BioGRID (affinity chromatography technology)
HPRD (in vivo)

		TBP	TAF7L
Gene Name		TATA box binding protein	TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Female Pronucleus Male Pronucleus Nucleoplasm Transcription Factor TFIID Complex Transcription Factor TFIIA Complex Nuclear Euchromatin Cytoplasm	Transcription Factor TFIID Complex Cytoplasm
	Molecular Function	RNA Polymerase II Repressing Transcription Factor Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Transcription Factor Binding Transcription Regulatory Region DNA Binding Repressing Transcription Factor Binding	Molecular_function
	Biological Process	Chromatin Silencing At RDNA Transcription From RNA Polymerase I Promoter Transcription Initiation From RNA Polymerase I Promoter Transcription Elongation From RNA Polymerase I Promoter Termination Of RNA Polymerase I Transcription Transcription From RNA Polymerase II Promoter Transcription Initiation From RNA Polymerase II Promoter Transcription Elongation From RNA Polymerase II Promoter Transcription From RNA Polymerase III Promoter Spermatogenesis Gene Expression Viral Process Regulation Of Gene Expression, Epigenetic Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Transcription, DNA-templated	Regulation Of Transcription, DNA-templated Transcription Initiation From RNA Polymerase II Promoter Multicellular Organismal Development Spermatogenesis Biological_process Cell Differentiation
Pathways		RNA Polymerase II Promoter Escape RNA Polymerase III Transcription Initiation From Type 3 Promoter RNA Polymerase II Transcription Pre-Initiation And Promoter Opening RNA Polymerase I Chain Elongation RNA Polymerase II Transcription RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase I Transcription Initiation RNA Polymerase I Promoter Clearance HIV Infection RNA Polymerase II Pre-transcription Events HIV Life Cycle HIV Transcription Initiation NoRC negatively regulates rRNA expression RNA Polymerase II HIV Promoter Escape RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I Transcription RNA Polymerase I Transcription Termination RNA Polymerase I Promoter Escape Epigenetic regulation of gene expression Negative epigenetic regulation of rRNA expression Late Phase of HIV Life Cycle RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase II Transcription Initiation And Promoter Clearance RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase II Transcription Initiation SIRT1 negatively regulates rRNA Expression Transcription of the HIV genome
Drugs
Diseases
GWAS		Type 1 diabetes ( 21980299)
Protein-Protein Interactions		113 interactors: ABT1 AHR AR ATF4 BCL3 BRD2 BRF1 BRF2 BTAF1 CAND2 CITED2 COL26A1 CREG1 CREM CTBP1 CTD CXXC1 DHX9 DR1 DRAP1 E2F1 EDF1 ELF3 ESR1 FATE1 FOS FOXF2 GOLGA2 GTF2A1 GTF2A1L GTF2A2 GTF2B GTF2E1 GTF2E2 GTF2F1 GTF2F2 GTF2H4 GTF3C2 GTF3C3 GTF3C4 GTF3C5 HAP1 HIST3H3 HMGB1 HNF4A HNRNPK HSF1 HTT IKZF1 JUN JUND KDM5A KLF5 MCM2 MDM2 MSX1 MYC NACA NCOA1 NCOA3 NCOA6 NFYB NFYC NR3C1 PAX3 PAX5 PAX6 PIAS1 PIAS3 POLR2A POLR3F POU2F1 POU2F2 POU3F2 PSMC2 RB1 REL RELA REST RNF4 RUVBL1 RUVBL2 RXRA SNAPC1 SNAPC2 SNAPC4 SP1 SPI1 SPIB SSX2IP SUB1 TAF1 TAF10 TAF11 TAF12 TAF13 TAF15 TAF1A TAF1B TAF1C TAF1L TAF5 TAF7L TCF12 TEAD1 TP53 TRAM2 TRIP4 UBE2I UBTF WDR62 YWHAE ZNF76	4 interactors: APP SRPK2 TAF1 TBP
Entrez ID		6908	54457
HPRD ID		02511	02259
Ensembl ID		ENSG00000112592	ENSG00000102387
Uniprot IDs		P20226 Q32MN6 Q32MN7	Q5H9L4
PDB IDs		1C9B 1CDW 1JFI 1NVP 1TGH
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Macromolecule Biosynthetic Process Cellular Macromolecule Biosynthetic Process Transcription From RNA Polymerase II Promoter Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Cellular Aromatic Compound Metabolic Process Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Biosynthetic Process Regulation Of Gene Expression Nitrogen Compound Metabolic Process Regulation Of Nitrogen Compound Metabolic Process Positive Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process DNA-templated Transcription, Initiation Positive Regulation Of Cellular Biosynthetic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Cellular Metabolic Process Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Metabolic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Cellular Metabolic Process Transcription Elongation From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Viral Process Negative Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Regulation Of Cellular Process Metabolic Process Chromosome Organization Chromatin Organization Chromatin Modification Transcription From RNA Polymerase III Promoter Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Cellular Metabolic Process Peptidyl-lysine Modification Histone Acetylation Internal Peptidyl-lysine Acetylation	Positive Regulation Of Gene Expression Transcription Elongation From RNA Polymerase II Promoter DNA-templated Transcription, Elongation Nuclear Speck Organization Transcription Initiation From RNA Polymerase II Promoter Synaptic Growth At Neuromuscular Junction RNA Metabolic Process Positive Regulation Of Metabolic Process Gene Expression Collateral Sprouting In Absence Of Injury RNA Polymerase II Transcriptional Preinitiation Complex Assembly DNA-templated Transcription, Initiation Protein Phosphorylation Positive Regulation Of Transcription, DNA-templated Collateral Sprouting Axon Midline Choice Point Recognition Positive Regulation Of Cell Cycle Positive Regulation Of Proteolysis Smooth Endoplasmic Reticulum Calcium Ion Homeostasis Positive Regulation Of Macromolecule Biosynthetic Process Axon Choice Point Recognition Positive Regulation Of Cellular Biosynthetic Process Regulation Of RNA Metabolic Process Nucleobase-containing Compound Metabolic Process Neuron Remodeling Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Phosphorylation MRNA Processing Regulation Of Gene Expression Cellular Component Assembly Regulation Of Nitrogen Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Positive Regulation Of Transcription Initiation From RNA Polymerase II Promoter Chromatin Silencing At RDNA Positive Regulation Of DNA-templated Transcription, Initiation MRNA Metabolic Process Nitrogen Compound Metabolic Process Cellular Copper Ion Homeostasis Viral Process RNA Processing Positive Regulation Of Viral Genome Replication Regulation Of DNA-templated Transcription, Initiation Copper Ion Homeostasis Suckling Behavior Cellular Macromolecular Complex Assembly Positive Regulation Of G2/M Transition Of Mitotic Cell Cycle Termination Of RNA Polymerase I Transcription Transcription Elongation From RNA Polymerase I Promoter Regulation Of Proteolysis
Tagcloud ?		60s analyzing cerevisiae codons defect efficiently encodes facilitates fflux firefly gfp homologue hsp70 inducible modest mutant polysome polysomes rarely saccharomyces strain surprisingly tata translated translation turnover ydj1 ydj1p yeast	azoospermia basepair bc043391 caucasian ethnic evolved exception exon flanking follicle fsh gonadal hormones infertile infertility intron introns mammals ncbi nonobstructive recruited reproductive semen specialised speculated spermatogenesis spermatogenic testicular trf
Tagcloud (Difference) ?		60s analyzing cerevisiae codons defect efficiently encodes facilitates fflux firefly gfp homologue hsp70 inducible modest mutant polysome polysomes rarely saccharomyces strain surprisingly tata translated translation turnover ydj1 ydj1p yeast	azoospermia basepair bc043391 caucasian ethnic evolved exception exon flanking follicle fsh gonadal hormones infertile infertility intron introns mammals ncbi nonobstructive recruited reproductive semen specialised speculated spermatogenesis spermatogenic testicular trf
Tagcloud (Intersection) ?