GTF3C5 and SRA1

Number of citations of the paper that reports this interaction (PubMedID 20398657)
0

Data Source:
BioGRID (far western blotting)

		GTF3C5	SRA1
Description		general transcription factor IIIC subunit 5	steroid receptor RNA activator 1
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GO Annotations	Cellular Component	Transcription Factor TFIIIC Complex Nucleus Nucleoplasm	Nucleus Nucleoplasm Cytoplasm Cytosol Plasma Membrane Cilium Microtubule Cytoskeleton Intercellular Bridge Ribonucleoprotein Complex
	Molecular Function	RNA Polymerase III General Transcription Initiation Factor Activity RNA Polymerase III Type 1 Promoter Sequence-specific DNA Binding RNA Polymerase III Type 2 Promoter Sequence-specific DNA Binding DNA Binding Protein Binding	Steroid Receptor RNA Activator RNA Binding Transcription Coactivator Activity Protein Binding
	Biological Process	Transcription By RNA Polymerase III Transcription Initiation At RNA Polymerase III Promoter Skeletal Muscle Cell Differentiation 5S Class RRNA Transcription By RNA Polymerase III TRNA Transcription By RNA Polymerase III	Regulation Of Transcription By RNA Polymerase II Apoptotic Process Negative Regulation Of Myoblast Differentiation Positive Regulation Of DNA-templated Transcription
Pathways		RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS		Sepsis (28-day mortality) ( 32592749)	Refractive error ( 32231278) Schizophrenia ( 28991256) Serum immune biomarker levels ( 32066700)
Interacting Genes		16 interacting genes: BRF1 DNMT3L GTF3C3 GTF3C4 KRT40 KRTAP10-3 KRTAP12-3 MDFI NOTCH2NLA OGT PTEN RPTOR SRA1 TBP TCF21 TCF4	30 interacting genes: ALX1 ATF1 ATF2 ATF3 ATF4 BLZF1 BTG2 CEBPA CREB1 DDIT3 DMTF1 E2F3 EGR1 EGR2 ESR1 ESR2 ESRRG ETS1 ETS2 FOS FOSB FOSL2 GATA1 GTF2B GTF2H2 GTF3C5 HAND1 NR3C1 TFAP2A UBE2Z
Entrez ID		9328	10011
HPRD ID		16077	18716
Ensembl ID		ENSG00000148308	ENSG00000213523
Uniprot IDs		H7BY84 Q9Y5Q8	Q9HD15
PDB IDs		8CLK	2MGX 4NBO
Enriched GO Terms of Interacting Partners?		RNA Polymerase III General Transcription Initiation Factor Activity Transcription By RNA Polymerase III TRNA Transcription RRNA Transcription TFIIB-class Transcription Factor Binding Transcription Factor TFIIIC Complex 5S Class RRNA Transcription By RNA Polymerase III Transcription Initiation At RNA Polymerase III Promoter DNA-templated Transcription Initiation TRNA Transcription By RNA Polymerase III Keratin Filament Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of DNA-templated Transcription Intermediate Filament RRNA Metabolic Process DNA-templated Transcription TRNA Metabolic Process Protein-DNA Complex Assembly Macromolecule Biosynthetic Process Transcription Preinitiation Complex Assembly Regulation Of DNA-templated Transcription Regulation Of RNA Metabolic Process Regulation Of RNA Biosynthetic Process Negative Regulation Of Synaptic Vesicle Clustering Social Behavior Phosphatidylinositol-3,4-bisphosphate 3-phosphatase Activity Negative Regulation Of Keratinocyte Migration Inositol-1,3,4,5-tetrakisphosphate 3-phosphatase Activity Positive Regulation Of RNA Metabolic Process Positive Regulation Of Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Inositol-1,3,4,5,6-pentakisphosphate 3-phosphatase Activity Positive Regulation Of Macromolecule Biosynthetic Process E-box Binding Protein Localization To Lysosome Protein N-acetylglucosaminyltransferase Complex Cellular Response To Glucose Stimulus Negative Regulation Of Non-canonical Inflammasome Complex Assembly Regulation Of Carbohydrate Catabolic Process Regulation Of Glycolytic Process Positive Regulation Of TORC1 Signaling Negative Regulation Of Translational Initiation Positive Regulation Of Translational Initiation TORC1 Signaling Steroid Receptor RNA Activator RNA Binding Negative Regulation Of DNA Methylation-dependent Heterochromatin Formation Regulation Of ATP Metabolic Process Cellular Response To Carbohydrate Stimulus Transcription Factor TFIIIB Complex Cellular Developmental Process	DNA-binding Transcription Factor Activity DNA-binding Transcription Activator Activity, RNA Polymerase II-specific Sequence-specific DNA Binding DNA-binding Transcription Factor Activity, RNA Polymerase II-specific Chromatin RNA Polymerase II Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Transcription By RNA Polymerase II DNA Binding Regulation Of Transcription By RNA Polymerase II Sequence-specific Double-stranded DNA Binding Positive Regulation Of RNA Metabolic Process RNA Polymerase II Transcription Regulator Complex RNA Polymerase II Transcription Regulatory Region Sequence-specific DNA Binding Positive Regulation Of DNA-templated Transcription Positive Regulation Of RNA Biosynthetic Process Positive Regulation Of Nucleobase-containing Compound Metabolic Process Nucleoplasm Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Transcription Cis-regulatory Region Binding Regulation Of RNA Metabolic Process Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Positive Regulation Of Biosynthetic Process Nucleus Negative Regulation Of Transcription By RNA Polymerase II Positive Regulation Of Macromolecule Metabolic Process DNA-templated Transcription Negative Regulation Of DNA-templated Transcription Negative Regulation Of RNA Biosynthetic Process Positive Regulation Of Metabolic Process Negative Regulation Of RNA Metabolic Process Transcription By RNA Polymerase II Macromolecule Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Nucleobase-containing Compound Metabolic Process Transcription Regulator Complex Regulation Of Macromolecule Biosynthetic Process Regulation Of Primary Metabolic Process Nucleobase-containing Compound Biosynthetic Process Regulation Of Macromolecule Metabolic Process Skeletal Muscle Cell Differentiation Regulation Of Metabolic Process Estrogen Response Element Binding Negative Regulation Of Macromolecule Biosynthetic Process Promoter-specific Chromatin Binding Negative Regulation Of Biosynthetic Process Response To Hormone ATF4-CREB1 Transcription Factor Complex
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