GTF3C5 and GTF3C4

Number of citations of the paper that reports this interaction (PMID 22939629)
44

Data Source:
BioGRID (biochemical)
HPRD (in vitro, in vivo)

		GTF3C5	GTF3C4
Gene Name		general transcription factor IIIC, polypeptide 5, 63kDa	general transcription factor IIIC, polypeptide 4, 90kDa
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Transcription Factor TFIIIC Complex Nucleoplasm	Transcription Factor TFIIIC Complex Nucleoplasm
	Molecular Function	DNA Binding Protein Binding	DNA Binding Histone Acetyltransferase Activity Protein Binding Enzyme Activator Activity
	Biological Process	Transcription, DNA-templated Transcription From RNA Polymerase III Promoter Gene Expression Skeletal Muscle Cell Differentiation 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter	Transcription, DNA-templated Transcription From RNA Polymerase III Promoter Transcription Initiation From RNA Polymerase III Promoter Gene Expression Histone Acetylation 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter Positive Regulation Of Catalytic Activity
Pathways		RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 2 Promoter	RNA Polymerase III Transcription RNA Polymerase III Transcription Initiation RNA Polymerase III Transcription Initiation From Type 1 Promoter RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription RNA Polymerase III Abortive And Retractive Initiation RNA Polymerase III Transcription Initiation From Type 2 Promoter
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: BRF1 GTF3C3 GTF3C4 GTF3C6 KRT40 KRTAP10-3 MDFI NOTCH2NL SRA1 TBP TCF21 TCF4	11 interactors: BRCA1 BRF1 GTF3C1 GTF3C2 GTF3C5 GTF3C6 HIST2H3A HIST3H3 POLR3C POLR3F TBP
Entrez ID		9328	9329
HPRD ID		16077	11998
Ensembl ID		ENSG00000148308
Uniprot IDs		H9KV68 Q9Y5Q8	B3KNH2 Q9UKN8
PDB IDs
Enriched GO Terms of Interacting Partners?		TRNA Transcription Transcription From RNA Polymerase III Promoter RRNA Transcription 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter Transcription, DNA-templated RNA Biosynthetic Process DNA-templated Transcription, Initiation RNA Metabolic Process Transcription Initiation From RNA Polymerase III Promoter Gene Expression Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Embryonic Organ Development Reproductive Structure Development Reproductive System Development Embryonic Digestive Tract Morphogenesis Nucleobase-containing Compound Metabolic Process Single Organism Reproductive Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Embryonic Morphogenesis Reproductive Process Cellular Nitrogen Compound Metabolic Process Embryonic Digestive Tract Development Developmental Process Involved In Reproduction Nitrogen Compound Metabolic Process Embryonic Organ Morphogenesis Transcription From RNA Polymerase II Promoter Digestive Tract Morphogenesis Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus Embryo Development Multicellular Organism Growth Embryonic Placenta Development Cell Differentiation Blood Vessel Development Vasculature Development Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Proepicardium Development Negative Regulation Of Gene Expression Digestive Tract Development Negative Regulation Of Biosynthetic Process Maintenance Of DNA Repeat Elements Bronchiole Development Digestive System Development	Transcription From RNA Polymerase III Promoter TRNA Transcription 5S Class RRNA Transcription From RNA Polymerase III Type 1 Promoter TRNA Transcription From RNA Polymerase III Promoter RRNA Transcription Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Regulation Of Transcription From RNA Polymerase III Promoter Transcription, DNA-templated Gene Expression RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process DNA-templated Transcription, Termination DNA-templated Transcription, Elongation RNA Metabolic Process Biosynthetic Process Chromatin Silencing At RDNA Termination Of RNA Polymerase III Transcription Transcription Elongation From RNA Polymerase III Promoter Positive Regulation Of Interferon-beta Production Cellular Metabolic Process Regulation Of Gene Expression, Epigenetic Chromatin Silencing Regulation Of Interferon-beta Production Positive Regulation Of Histone H4-K20 Methylation Positive Regulation Of Histone H4-K16 Acetylation Positive Regulation Of Cytokine Production Negative Regulation Of Gene Expression, Epigenetic Positive Regulation Of Type I Interferon Production Positive Regulation Of Histone H3-K9 Acetylation Gene Silencing Regulation Of Type I Interferon Production Positive Regulation Of Histone H4 Acetylation Negative Regulation Of Histone H3-K4 Methylation Proepicardium Development Regulation Of Cytokine Production Cellular Response To Indole-3-methanol Defense Response To Virus Metabolic Process Negative Regulation Of Centriole Replication Dosage Compensation By Inactivation Of X Chromosome Positive Regulation Of Innate Immune Response Protein K6-linked Ubiquitination Negative Regulation Of Histone H3-K9 Methylation Positive Regulation Of Histone H3-K9 Methylation Dosage Compensation
Tagcloud ?		acetylated allowing architecture became branching chipseq coordinated depolarization depolarizing discovered dramatic factories interplay interspersed mimicked nee rearrangement relies relocated relocation remarkably silencing sines somatosensory synaptic tfiiic tfs timely uncontrolled
Tagcloud (Difference) ?		acetylated allowing architecture became branching chipseq coordinated depolarization depolarizing discovered dramatic factories interplay interspersed mimicked nee rearrangement relies relocated relocation remarkably silencing sines somatosensory synaptic tfiiic tfs timely uncontrolled
Tagcloud (Intersection) ?