COPB2 and COPA

Number of citations of the paper that reports this interaction (PMID 8537409)
27

Data Source:
HPRD (in vivo)

		COPB2	COPA
Gene Name		coatomer protein complex, subunit beta 2 (beta prime)	coatomer protein complex, subunit alpha
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Cytosol COPI Vesicle Coat	Extracellular Space Cytoplasm Cytosol Membrane COPI Vesicle Coat Extracellular Vesicular Exosome
	Molecular Function	Structural Molecule Activity	Hormone Activity Structural Molecule Activity
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Intra-Golgi Vesicle-mediated Transport COPI Coating Of Golgi Vesicle Membrane Organization	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Pancreatic Juice Secretion COPI Coating Of Golgi Vesicle Membrane Organization
Pathways		COPI Mediated Transport Golgi to ER Retrograde Transport	COPI Mediated Transport Golgi to ER Retrograde Transport
Drugs
Diseases
GWAS		Kawasaki disease ( 22446961)
Protein-Protein Interactions		10 interactors: ARCN1 COPA COPE NDRG1 NFKB1 PRKCE RGS2 RGS4 SACM1L TMED10	12 interactors: ARCN1 ARFGAP1 COPB2 COPE COPZ1 MTNR1B PDGFRB SACM1L SLC25A11 STX8 TMED10 TMED2
Entrez ID		9276	1314
HPRD ID		06103	03564
Ensembl ID		ENSG00000184432	ENSG00000122218
Uniprot IDs		P35606	P53621
PDB IDs
Enriched GO Terms of Interacting Partners?		COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Retrograde Vesicle-mediated Transport, Golgi To ER Localization Within Membrane Vesicle Targeting Membrane Budding Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Golgi Vesicle Transport Establishment Of Organelle Localization Membrane Organization Organelle Localization Response To Alkaloid Vesicle-mediated Transport Intracellular Transport Termination Of G-protein Coupled Receptor Signaling Pathway Termination Of Signal Transduction MyD88-independent Toll-like Receptor Signaling Pathway Positive Regulation Of Cellular Glucuronidation Cerebellar Purkinje Cell Layer Maturation Negative Regulation Of Interleukin-12 Biosynthetic Process Toll-like Receptor 4 Signaling Pathway Negative Regulation Of MAP Kinase Activity Regulation Of Phospholipase Activity Establishment Of Localization In Cell Negative Regulation Of G-protein Coupled Receptor Protein Signaling Pathway Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels ER To Golgi Vesicle-mediated Transport TRAM-dependent Toll-like Receptor 4 Signaling Pathway Toll-like Receptor Signaling Pathway Cellular Response To Oxygen Levels Regulation Of Protein Metabolic Process Positive Regulation Of Protein Polymerization Negative Regulation Of Calcidiol 1-monooxygenase Activity Positive Regulation Of Hyaluronan Biosynthetic Process Cerebellum Maturation Pattern Recognition Receptor Signaling Pathway Innate Immune Response-activating Signal Transduction Negative Regulation Of Protein Serine/threonine Kinase Activity Activation Of Innate Immune Response Cellular Localization Regulation Of Carbohydrate Metabolic Process Regulation Of MAPK Cascade Cellular Response To Lipopolysaccharide Protein Transport Negative Regulation Of MAPK Cascade	COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Localization Within Membrane Vesicle Targeting Membrane Budding Retrograde Vesicle-mediated Transport, Golgi To ER Vesicle Organization Establishment Of Vesicle Localization Vesicle Localization Golgi Vesicle Transport Establishment Of Organelle Localization Organelle Localization Membrane Organization Protein Transport Vesicle-mediated Transport Intracellular Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Establishment Of Localization In Cell Cellular Protein Localization Organelle Organization Intra-Golgi Vesicle-mediated Transport Cellular Localization Cargo Loading Into Vesicle ER To Golgi Vesicle-mediated Transport COPII Vesicle Coating COPII-coated Vesicle Budding Transport Cytoplasmic Transport Cell Migration Involved In Coronary Angiogenesis Cerebellar Purkinje Cell Layer Maturation Metanephric Mesenchymal Cell Migration Golgi Organization Angiogenesis Involved In Coronary Vascular Morphogenesis Cell Migration Involved In Kidney Development Alpha-ketoglutarate Transport Positive Regulation Of Cell Proliferation By VEGF-activated Platelet Derived Growth Factor Receptor Signaling Pathway Smooth Muscle Cell Chemotaxis Cerebellum Maturation Metanephric Comma-shaped Body Morphogenesis Positive Regulation Of Metanephric Mesenchymal Cell Migration By Platelet-derived Growth Factor Receptor-beta Signaling Pathway Metanephric Glomerular Mesangial Cell Proliferation Involved In Metanephros Development Cell Migration Involved In Vasculogenesis Metanephric S-shaped Body Morphogenesis Glomerular Mesangial Cell Proliferation Positive Regulation Of Metanephric Mesenchymal Cell Migration Comma-shaped Body Morphogenesis
Tagcloud ?		addiction axonogenesis bnip4 camk1gammab candidates classes cns dao dendritogenesis deregulation differentially dopaminergic glutamatergic grb2 great grik indicative magi1b morphine mu neurotransmission opioid otpb patterning serotonergic sox19b whose wls zebrafish	atpases cgr cognate copb copper copz copz1 copz2 corynebacterium csor derepression efflux encode exporter glutamicum implied lacz metallochaperone monocistronic multilayered nickel operon redundant regulon repressor talk uniquely zinc zur
Tagcloud (Difference) ?		addiction axonogenesis bnip4 camk1gammab candidates classes cns dao dendritogenesis deregulation differentially dopaminergic glutamatergic grb2 great grik indicative magi1b morphine mu neurotransmission opioid otpb patterning serotonergic sox19b whose wls zebrafish	atpases cgr cognate copb copper copz copz1 copz2 corynebacterium csor derepression efflux encode exporter glutamicum implied lacz metallochaperone monocistronic multilayered nickel operon redundant regulon repressor talk uniquely zinc zur
Tagcloud (Intersection) ?