COPA and WBP1

Number of citations of the paper that reports this interaction (PubMedID 25894502)
46

Data Source:
BioGRID (unspecified method)

		COPA	WBP1
Description		coat protein complex I subunit alpha	WW domain binding protein 1
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GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Extracellular Space Cytoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Membrane Coat COPI Vesicle Coat Transport Vesicle COPI-coated Vesicle Growth Cone COPI-coated Vesicle Membrane Cytoplasmic Vesicle Extracellular Exosome
	Molecular Function	MRNA Binding Hormone Activity Structural Molecule Activity Protein Binding	Protein Binding WW Domain Binding
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Signal Transduction Protein Transport Vesicle-mediated Transport Pancreatic Juice Secretion Protein Localization To Axon Protein Localization To Cell Leading Edge
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic
Drugs
Diseases
GWAS		Breast size ( 27182965)
Interacting Genes		21 interacting genes: ARCN1 ARFGAP1 CDC42 COPB2 COPE DUX4 HUNK MTNR1B PDGFRB PTEN RBM11 RUNX1 SACM1L SCYL1 SLC25A11 STX8 SUMO2 TMED10 TMED2 WBP1 WBP2	10 interacting genes: CACNA1A COPA EPN2 MAGI1 NEDD4 SMCO4 WWP1 WWP2 YAP1 ZMYND10
Entrez ID		1314	23559
HPRD ID		03564	09510
Ensembl ID		ENSG00000122218	ENSG00000239779
Uniprot IDs		P53621	A0A384P602 Q96G27
PDB IDs		6PBG 6TZT 6U3V	1JMQ 1K5R
Enriched GO Terms of Interacting Partners?		COPI-coated Vesicle Membrane COPI-coated Vesicle COPI Vesicle Coat Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Transport Vesicle Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle-mediated Transport Golgi Membrane Golgi Vesicle Transport Golgi Apparatus COPI Coating Of Golgi Vesicle Establishment Of Protein Localization Golgi Localization Intracellular Protein Localization Phosphatidylinositol-3-phosphate Phosphatase Activity Endoplasmic Reticulum-Golgi Intermediate Compartment Endoplasmic Reticulum Membrane Cell Migration Involved In Heart Development Zymogen Granule Membrane Protein Transport Dendritic Spine Morphogenesis Cytoplasmic Vesicle Intracellular Transport Intracellular Protein Transport Golgi Organization Phosphatidylinositol Dephosphorylation COPII Vesicle Coating Vesicle Cargo Loading Dendritic Spine Organization Intra-Golgi Vesicle-mediated Transport Membrane Organization Phospholipid Dephosphorylation COPII-coated ER To Golgi Transport Vesicle Vesicle Coating Cell Migration Involved In Coronary Angiogenesis Metanephric Glomerular Mesangial Cell Proliferation Involved In Metanephros Development Negative Regulation Of Synaptic Vesicle Clustering Oxoglutarate:malate Antiporter Activity Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Neuron Projection Organization Postsynapse Organization Cis-Golgi Network Cellular Localization Establishment Of Localization In Cell Syntaxin Binding Cerebellar Purkinje Cell Layer Maturation GBD Domain Binding Storage Vacuole	Negative Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of Potassium Ion Export Across Plasma Membrane Potassium Channel Inhibitor Activity Negative Regulation Of Potassium Ion Export Across Plasma Membrane Regulation Of Notch Signaling Pathway Ubiquitin Ligase Complex Proline-rich Region Binding Negative Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Potassium Ion Transport Regulation Of Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Notch Signaling Pathway Ubiquitin-protein Transferase Activity Mesenchyme Development Formation Of Structure Involved In A Symbiotic Process Enterocyte Differentiation Positive Regulation Of Motile Cilium Assembly Regulation Of Potassium Ion Transmembrane Transport Negative Regulation Of Cation Transmembrane Transport Protein K63-linked Ubiquitination Negative Regulation Of Monoatomic Ion Transmembrane Transport Ubiquitin Protein Ligase Activity Regulation Of Potassium Ion Transport Channel Inhibitor Activity Anchoring Junction Regulation Of Cilium Assembly Negative Regulation Of Monoatomic Ion Transport Membrane Phosphothreonine Residue Binding TEAD-YAP Complex Cytoplasm Protein Localization To Cell Leading Edge Nuclear Receptor-mediated Glucocorticoid Signaling Pathway Negative Regulation Of Cellular Response To Growth Factor Stimulus Negative Regulation Of Transmembrane Transport Bicellular Tight Junction Lateral Mesoderm Development Cardiac Muscle Tissue Regeneration Symbiont Entry Into Host Cell Pancreatic Juice Secretion Transmembrane Transporter Binding Nuclear Receptor-mediated Corticosteroid Signaling Pathway Phosphoserine Residue Binding Beta-2 Adrenergic Receptor Binding Ubiquitin-dependent Protein Catabolic Process Regulation Of Metanephric Nephron Tubule Epithelial Cell Differentiation Modification-dependent Protein Catabolic Process Biological Process Involved In Interaction With Host
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