COPA and SLC25A11

Number of citations of the paper that reports this interaction (PMID 16169070)
531

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		COPA	SLC25A11
Gene Name		coatomer protein complex, subunit alpha	solute carrier family 25 (mitochondrial carrier; oxoglutarate carrier), member 11
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Membrane COPI Vesicle Coat Extracellular Vesicular Exosome	Nucleus Mitochondrion Mitochondrial Inner Membrane Integral Component Of Plasma Membrane
	Molecular Function	Hormone Activity Structural Molecule Activity	Oxoglutarate:malate Antiporter Activity Poly(A) RNA Binding
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Pancreatic Juice Secretion COPI Coating Of Golgi Vesicle Membrane Organization	Carbohydrate Metabolic Process Glucose Metabolic Process Gluconeogenesis Transport Pathogenesis Alpha-ketoglutarate Transport Small Molecule Metabolic Process
Pathways		COPI Mediated Transport Golgi to ER Retrograde Transport	Gluconeogenesis Glucose metabolism Myoclonic epilepsy of Lafora Glycogen storage diseases Metabolism of carbohydrates
Drugs
Diseases
GWAS
Protein-Protein Interactions		12 interactors: ARCN1 ARFGAP1 COPB2 COPE COPZ1 MTNR1B PDGFRB SACM1L SLC25A11 STX8 TMED10 TMED2	2 interactors: CDKN1A COPA
Entrez ID		1314	8402
HPRD ID		03564	05003
Ensembl ID		ENSG00000122218	ENSG00000108528
Uniprot IDs		P53621	Q02978 Q6IBH0
PDB IDs
Enriched GO Terms of Interacting Partners?		COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Localization Within Membrane Vesicle Targeting Membrane Budding Retrograde Vesicle-mediated Transport, Golgi To ER Vesicle Organization Establishment Of Vesicle Localization Vesicle Localization Golgi Vesicle Transport Establishment Of Organelle Localization Organelle Localization Membrane Organization Protein Transport Vesicle-mediated Transport Intracellular Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Establishment Of Localization In Cell Cellular Protein Localization Organelle Organization Intra-Golgi Vesicle-mediated Transport Cellular Localization Cargo Loading Into Vesicle ER To Golgi Vesicle-mediated Transport COPII Vesicle Coating COPII-coated Vesicle Budding Transport Cytoplasmic Transport Cell Migration Involved In Coronary Angiogenesis Cerebellar Purkinje Cell Layer Maturation Metanephric Mesenchymal Cell Migration Golgi Organization Angiogenesis Involved In Coronary Vascular Morphogenesis Cell Migration Involved In Kidney Development Alpha-ketoglutarate Transport Positive Regulation Of Cell Proliferation By VEGF-activated Platelet Derived Growth Factor Receptor Signaling Pathway Smooth Muscle Cell Chemotaxis Cerebellum Maturation Metanephric Comma-shaped Body Morphogenesis Positive Regulation Of Metanephric Mesenchymal Cell Migration By Platelet-derived Growth Factor Receptor-beta Signaling Pathway Metanephric Glomerular Mesangial Cell Proliferation Involved In Metanephros Development Cell Migration Involved In Vasculogenesis Metanephric S-shaped Body Morphogenesis Glomerular Mesangial Cell Proliferation Positive Regulation Of Metanephric Mesenchymal Cell Migration Comma-shaped Body Morphogenesis	Intestinal Epithelial Cell Maturation Pancreatic Juice Secretion Cellular Response To UV-B Stress-induced Premature Senescence COPI Coating Of Golgi Vesicle COPI-coated Vesicle Budding Golgi Vesicle Budding Mitotic Cell Cycle Arrest Intestinal Epithelial Cell Development Response To UV-B Regulation Of Protein Import Into Nucleus, Translocation Intestinal Epithelial Cell Differentiation Epithelial Cell Maturation Response To Arsenic-containing Substance Negative Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Vesicle Targeting, To, From Or Within Golgi Cellular Senescence Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage By P53 Class Mediator Response To X-ray Response To Hyperoxia Response To Corticosterone Retrograde Vesicle-mediated Transport, Golgi To ER Response To Mineralocorticoid Positive Regulation Of B Cell Proliferation Localization Within Membrane Vesicle Targeting Columnar/cuboidal Epithelial Cell Development Intrinsic Apoptotic Signaling Pathway By P53 Class Mediator Regulation Of DNA Biosynthetic Process DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Cell Cycle Arrest Signal Transduction Involved In Mitotic G1 DNA Damage Checkpoint Regulation Of B Cell Proliferation Cellular Response To Ionizing Radiation Signal Transduction Involved In DNA Damage Checkpoint Cellular Response To UV Signal Transduction Involved In Cell Cycle Checkpoint Cellular Response To Heat Positive Regulation Of Fibroblast Proliferation Mitotic G1 DNA Damage Checkpoint Cell Aging Mitotic G1/S Transition Checkpoint G1 DNA Damage Checkpoint Organ Regeneration Positive Regulation Of Cell Cycle Arrest Positive Regulation Of B Cell Activation Membrane Budding DNA Damage Response, Signal Transduction By P53 Class Mediator Positive Regulation Of Reactive Oxygen Species Metabolic Process Signal Transduction In Response To DNA Damage Cellular Response To Light Stimulus
Tagcloud ?		atpases cgr cognate copb copper copz copz1 copz2 corynebacterium csor derepression efflux encode exporter glutamicum implied lacz metallochaperone monocistronic multilayered nickel operon redundant regulon repressor talk uniquely zinc zur	aggravating anxa1 banks bedside confidently cons fth1 ftl gliosis got2 immunochemical infarct infarcted infarcts itraq lagging leak malate mdh2 mortem plex pros proteome proteomics putamen shuttle tca vim
Tagcloud (Difference) ?		atpases cgr cognate copb copper copz copz1 copz2 corynebacterium csor derepression efflux encode exporter glutamicum implied lacz metallochaperone monocistronic multilayered nickel operon redundant regulon repressor talk uniquely zinc zur	aggravating anxa1 banks bedside confidently cons fth1 ftl gliosis got2 immunochemical infarct infarcted infarcts itraq lagging leak malate mdh2 mortem plex pros proteome proteomics putamen shuttle tca vim
Tagcloud (Intersection) ?