COPA and SLC25A11

Number of citations of the paper that reports this interaction (PubMedID 16169070)
0

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		COPA	SLC25A11
Description		coat protein complex I subunit alpha	solute carrier family 25 member 11
Image			No pdb structure
GO Annotations	Cellular Component	Golgi Membrane Extracellular Region Extracellular Space Cytoplasm Endoplasmic Reticulum Membrane Golgi Apparatus Cytosol Membrane Membrane Coat COPI Vesicle Coat Transport Vesicle COPI-coated Vesicle Growth Cone COPI-coated Vesicle Membrane Cytoplasmic Vesicle Extracellular Exosome	Nucleus Mitochondrion Mitochondrial Inner Membrane Plasma Membrane Membrane
	Molecular Function	MRNA Binding Hormone Activity Structural Molecule Activity Protein Binding	RNA Binding Protein Binding Alpha-ketoglutarate Transmembrane Transporter Activity Antiporter Activity Oxoglutarate:malate Antiporter Activity Transmembrane Transporter Activity
	Biological Process	Intracellular Protein Transport Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Intra-Golgi Vesicle-mediated Transport Signal Transduction Protein Transport Vesicle-mediated Transport Pancreatic Juice Secretion Protein Localization To Axon Protein Localization To Cell Leading Edge	Gluconeogenesis Lipid Transport Alpha-ketoglutarate Transport Malate-aspartate Shuttle Transmembrane Transport Malate Transmembrane Transport
Pathways		COPI-mediated anterograde transport COPI-dependent Golgi-to-ER retrograde traffic	Organic anion transport by SLC5/17/25 transporters Malate-aspartate shuttle
Drugs
Diseases
GWAS		Breast size ( 27182965)	Platelet count ( 27863252) Platelet distribution width ( 27863252 32888494) Plateletcrit ( 27863252)
Interacting Genes		21 interacting genes: ARCN1 ARFGAP1 CDC42 COPB2 COPE DUX4 HUNK MTNR1B PDGFRB PTEN RBM11 RUNX1 SACM1L SCYL1 SLC25A11 STX8 SUMO2 TMED10 TMED2 WBP1 WBP2	5 interacting genes: C5AR2 CDKN1A COPA SLC22A1 WEE2-AS1
Entrez ID		1314	8402
HPRD ID		03564	05003
Ensembl ID		ENSG00000122218	ENSG00000108528
Uniprot IDs		P53621	Q02978 Q6IBH0
PDB IDs		6PBG 6TZT 6U3V
Enriched GO Terms of Interacting Partners?		COPI-coated Vesicle Membrane COPI-coated Vesicle COPI Vesicle Coat Retrograde Vesicle-mediated Transport, Golgi To Endoplasmic Reticulum Transport Vesicle Endoplasmic Reticulum To Golgi Vesicle-mediated Transport Vesicle-mediated Transport Golgi Membrane Golgi Vesicle Transport Golgi Apparatus COPI Coating Of Golgi Vesicle Establishment Of Protein Localization Golgi Localization Intracellular Protein Localization Phosphatidylinositol-3-phosphate Phosphatase Activity Endoplasmic Reticulum-Golgi Intermediate Compartment Endoplasmic Reticulum Membrane Cell Migration Involved In Heart Development Zymogen Granule Membrane Protein Transport Dendritic Spine Morphogenesis Cytoplasmic Vesicle Intracellular Transport Intracellular Protein Transport Golgi Organization Phosphatidylinositol Dephosphorylation COPII Vesicle Coating Vesicle Cargo Loading Dendritic Spine Organization Intra-Golgi Vesicle-mediated Transport Membrane Organization Phospholipid Dephosphorylation COPII-coated ER To Golgi Transport Vesicle Vesicle Coating Cell Migration Involved In Coronary Angiogenesis Metanephric Glomerular Mesangial Cell Proliferation Involved In Metanephros Development Negative Regulation Of Synaptic Vesicle Clustering Oxoglutarate:malate Antiporter Activity Cytosol To ERGIC Protein Transport Protein Localization To ERGIC COPI-coated Vesicle Budding Neuron Projection Organization Postsynapse Organization Cis-Golgi Network Cellular Localization Establishment Of Localization In Cell Syntaxin Binding Cerebellar Purkinje Cell Layer Maturation GBD Domain Binding Storage Vacuole	PCNA-p21 Complex Negative Regulation Of Cardiac Muscle Tissue Regeneration Cellular Response To Cell-matrix Adhesion Protein Localization To Cell Leading Edge Pancreatic Juice Secretion (R)-carnitine Transmembrane Transport Acetylcholine Transport Pyrimidine Nucleoside Transmembrane Transporter Activity (R)-carnitine Transmembrane Transporter Activity Spermidine Transport Basal Plasma Membrane Metanephric Proximal Tubule Development Epinephrine Transport Norepinephrine:sodium Symporter Activity (R)-carnitine Transport Spermidine Transmembrane Transport Putrescine Transport Thiamine Transmembrane Transporter Activity Thiamine Transport Quaternary Ammonium Group Transmembrane Transporter Activity Dopamine:sodium Symporter Activity Spermidine Transmembrane Transporter Activity Putrescine Transmembrane Transporter Activity O-acyl-L-carnitine Transmembrane Transport Thiamine Transmembrane Transport Acetylcholine Transmembrane Transporter Activity Complement Component C5a Receptor Activity Complement Component C5a Signaling Pathway Negative Regulation Of Neutrophil Chemotaxis Pre-mRNA 5'-splice Site Binding Oncogene-induced Cell Senescence Stress-induced Premature Senescence Carnitine Transport Norepinephrine Uptake Xenobiotic Transport Across Blood-brain Barrier Toxin Transmembrane Transporter Activity Proximal Tubule Development Carnitine Transmembrane Transport Polyamine Transmembrane Transport Negative Regulation Of Neutrophil Migration Serotonin Uptake Norepinephrine Transport Complement Receptor Activity MRNA 5'-splice Site Recognition Prostaglandin Transmembrane Transporter Activity Monoamine Transmembrane Transporter Activity Negative Regulation Of Cyclin-dependent Protein Kinase Activity Protein Localization To Axon Establishment Or Maintenance Of Transmembrane Electrochemical Gradient Organic Cation Transmembrane Transporter Activity
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