COPA and TMED10

Number of citations of the paper that reports this interaction (PMID 9751720)
22

Data Source:
BioGRID (pull down)

		COPA	TMED10
Gene Name		coatomer protein complex, subunit alpha	transmembrane emp24-like trafficking protein 10 (yeast)
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Extracellular Space Cytoplasm Cytosol Membrane COPI Vesicle Coat Extracellular Vesicular Exosome	Golgi Membrane Endoplasmic Reticulum Endoplasmic Reticulum Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Golgi Apparatus Cis-Golgi Network Plasma Membrane Integral Component Of Membrane COPI-coated Vesicle Trans-Golgi Network Transport Vesicle Transport Vesicle Membrane Secretory Granule Membrane Endoplasmic Reticulum-Golgi Intermediate Compartment Membrane Melanosome Zymogen Granule Membrane Extracellular Vesicular Exosome Gamma-secretase Complex
	Molecular Function	Hormone Activity Structural Molecule Activity	Protein Binding Syntaxin Binding Protein Complex Binding
	Biological Process	Intracellular Protein Transport Retrograde Vesicle-mediated Transport, Golgi To ER Pancreatic Juice Secretion COPI Coating Of Golgi Vesicle Membrane Organization	Kidney Development Intracellular Protein Transport ER To Golgi Vesicle-mediated Transport Retrograde Vesicle-mediated Transport, Golgi To ER Golgi Organization Cargo Loading Into Vesicle COPI-coated Vesicle Budding Response To Alkaloid Regulated Secretory Pathway Vesicle Targeting, To, From Or Within Golgi COPI Coating Of Golgi Vesicle COPII Vesicle Coating Protein Oligomerization Regulation Of Beta-amyloid Formation
Pathways		COPI Mediated Transport Golgi to ER Retrograde Transport
Drugs
Diseases
GWAS			Height ( 19343178)
Protein-Protein Interactions		12 interactors: ARCN1 ARFGAP1 COPB2 COPE COPZ1 MTNR1B PDGFRB SACM1L SLC25A11 STX8 TMED10 TMED2	15 interactors: APH1A ARCN1 ARF1 COPA COPB1 COPB2 COPE COPG1 COPZ1 DHODH GORASP2 NCSTN PSENEN SEC23B TMED2
Entrez ID		1314	10972
HPRD ID		03564	12013
Ensembl ID		ENSG00000122218	ENSG00000170348
Uniprot IDs		P53621	B4DL12 P49755
PDB IDs
Enriched GO Terms of Interacting Partners?		COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Localization Within Membrane Vesicle Targeting Membrane Budding Retrograde Vesicle-mediated Transport, Golgi To ER Vesicle Organization Establishment Of Vesicle Localization Vesicle Localization Golgi Vesicle Transport Establishment Of Organelle Localization Organelle Localization Membrane Organization Protein Transport Vesicle-mediated Transport Intracellular Protein Transport Establishment Of Protein Localization Intracellular Transport Protein Localization Establishment Of Localization In Cell Cellular Protein Localization Organelle Organization Intra-Golgi Vesicle-mediated Transport Cellular Localization Cargo Loading Into Vesicle ER To Golgi Vesicle-mediated Transport COPII Vesicle Coating COPII-coated Vesicle Budding Transport Cytoplasmic Transport Cell Migration Involved In Coronary Angiogenesis Cerebellar Purkinje Cell Layer Maturation Metanephric Mesenchymal Cell Migration Golgi Organization Angiogenesis Involved In Coronary Vascular Morphogenesis Cell Migration Involved In Kidney Development Alpha-ketoglutarate Transport Positive Regulation Of Cell Proliferation By VEGF-activated Platelet Derived Growth Factor Receptor Signaling Pathway Smooth Muscle Cell Chemotaxis Cerebellum Maturation Metanephric Comma-shaped Body Morphogenesis Positive Regulation Of Metanephric Mesenchymal Cell Migration By Platelet-derived Growth Factor Receptor-beta Signaling Pathway Metanephric Glomerular Mesangial Cell Proliferation Involved In Metanephros Development Cell Migration Involved In Vasculogenesis Metanephric S-shaped Body Morphogenesis Glomerular Mesangial Cell Proliferation Positive Regulation Of Metanephric Mesenchymal Cell Migration Comma-shaped Body Morphogenesis	COPI-coated Vesicle Budding COPI Coating Of Golgi Vesicle Golgi Vesicle Budding Vesicle Targeting, To, From Or Within Golgi Localization Within Membrane Vesicle Targeting Retrograde Vesicle-mediated Transport, Golgi To ER Membrane Budding Golgi Vesicle Transport Establishment Of Vesicle Localization Vesicle Organization Vesicle Localization Establishment Of Organelle Localization Organelle Localization Membrane Organization Protein Transport Vesicle-mediated Transport Establishment Of Protein Localization Intracellular Transport Intracellular Protein Transport Protein Localization Intra-Golgi Vesicle-mediated Transport Establishment Of Localization In Cell Amyloid Precursor Protein Catabolic Process Membrane Protein Intracellular Domain Proteolysis Membrane Protein Ectodomain Proteolysis Amyloid Precursor Protein Metabolic Process Cellular Localization Notch Receptor Processing Cellular Protein Localization Membrane Protein Proteolysis Organelle Organization Transport Ephrin Receptor Signaling Pathway ER To Golgi Vesicle-mediated Transport Notch Signaling Pathway Neurotrophin TRK Receptor Signaling Pathway Neurotrophin Signaling Pathway Protein Processing Positive Regulation Of Apoptotic Process Positive Regulation Of Programmed Cell Death Positive Regulation Of Cell Death Cerebellar Purkinje Cell Layer Maturation Apoptotic Signaling Pathway Axon Guidance Cerebellum Maturation 'de Novo' UMP Biosynthetic Process Body Fluid Secretion Axonogenesis Establishment Of Golgi Localization
Tagcloud ?		atpases cgr cognate copb copper copz copz1 copz2 corynebacterium csor derepression efflux encode exporter glutamicum implied lacz metallochaperone monocistronic multilayered nickel operon redundant regulon repressor talk uniquely zinc zur	aiming aip alignment boar brms1 chordc1 clues cops6 csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmem70 y2h
Tagcloud (Difference) ?		atpases cgr cognate copb copper copz copz1 copz2 corynebacterium csor derepression efflux encode exporter glutamicum implied lacz metallochaperone monocistronic multilayered nickel operon redundant regulon repressor talk uniquely zinc zur	aiming aip alignment boar brms1 chordc1 clues cops6 csde1 csfv ddx5 domestic fever gnb2l1 hemorrhagic hspa8 interactive metap2 nav1 ncbi ns5a phf5a polr1c ppp2r3c psmc3 suvec swine tmem70 y2h
Tagcloud (Intersection) ?