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CD247 and CD244
Number of citations of the paper that reports this interaction (PubMedID
16049493
)
0
Data Source:
HPRD
(in vitro)
CD247
CD244
Description
CD247 molecule
CD244 molecule
Image
No pdb structure
GO Annotations
Cellular Component
Cytoplasm
Golgi Apparatus
Plasma Membrane
Membrane
Fc-gamma Receptor III Complex
T Cell Receptor Complex
Alpha-beta T Cell Receptor Complex
Gamma-delta T Cell Receptor Complex
Plasma Membrane Protein Complex
Plasma Membrane
External Side Of Plasma Membrane
Membrane
Membrane Raft
Molecular Function
Transmembrane Signaling Receptor Activity
Protein Binding
Identical Protein Binding
Protein Homodimerization Activity
Protein Heterodimerization Activity
Protein Tyrosine Kinase Binding
Protein Binding
Signaling Receptor Activity
MHC Class I Protein Binding
Biological Process
Adaptive Immune Response
Immune System Process
Cell Surface Receptor Signaling Pathway
Fc-gamma Receptor Signaling Pathway
Gamma-delta T Cell Activation
Alpha-beta T Cell Activation
T Cell Receptor Signaling Pathway
Protein Complex Oligomerization
Protein-containing Complex Assembly
Positive Regulation Of Protein Localization To Cell Surface
Adaptive Immune Response
Natural Killer Cell Activation Involved In Immune Response
Immune System Process
Immune Response
Signal Transduction
Natural Killer Cell Activation
Positive Regulation Of Type II Interferon Production
Positive Regulation Of Interleukin-8 Production
Innate Immune Response
Positive Regulation Of Inositol Phosphate Biosynthetic Process
Positive Regulation Of Granzyme B Production
Pathways
Cell surface interactions at the vascular wall
Drugs
Muromonab
Teclistamab
Odronextamab
Diseases
GWAS
Allergic disease (asthma, hay fever or eczema) (
29083406
29785011
)
Allergic rhinitis (
31361310
)
Asthma (
34103634
31361310
31619474
31959851
32296059
30929738
27182965
)
Asthma (adult onset) (
30929738
)
Asthma (childhood onset) (
30929738
)
Asthma (moderate or severe) (
30552067
)
Asthma or allergic disease (pleiotropy) (
29785011
)
Autoimmune thyroid disease (
32581359
)
Celiac disease (
20190752
)
Celiac disease or Rheumatoid arthritis (
21383967
)
Eosinophil count (
32888494
)
Eosinophil percentage of white cells (
32888494
)
Medication use (adrenergics, inhalants) (
31015401
)
Medication use (glucocorticoids) (
31015401
)
Medication use (thyroid preparations) (
31015401
)
Pre-treatment viral load in HIV-1 infection (
31219150
)
Systemic sclerosis (
31672989
29293537
21779181
21750679
20383147
)
Crohn's disease (
21102463
)
Inflammatory bowel disease (
23128233
)
Lymphocyte percentage of white cells (
32888494
)
Neutrophil percentage of white cells (
32888494
)
White blood cell count (
32888494
)
Interacting Genes
38 interacting genes:
CD2
CD244
CD28
CD3D
CD48
CD5
CSK
DOCK2
FCGR3A
FYN
GAB2
GRB2
JAK3
LCK
LY6E
NCR1
NCR3
PCGF2
PI4K2B
PTPN22
PTPN3
PTPN6
PTPRC
SH2B3
SHC1
SLA
SLA2
STAT5A
STAT5B
TFRC
TIRAP
TRA
TRAT1
TRB
UNC119
VTN
ZAP70
ZNF281
5 interacting genes:
ARHGEF7
CD247
CD48
LAT
SH2D1B
Entrez ID
919
51744
HPRD ID
01729
16121
Ensembl ID
ENSG00000198821
ENSG00000122223
Uniprot IDs
A0A8V8TPP4
A0A8V8TQM0
P20963
Q6KAV0
Q9BZW8
PDB IDs
1TCE
1YGR
2HAC
2OQ1
3IK5
3IOZ
4XZ1
6JXR
7FJD
7FJE
7FJF
7PHR
8ES7
8ES8
8ES9
8J8I
8JC0
8JCB
8TW4
8TW6
8WXE
8WY0
8WYI
8YC0
9BBC
9C3E
9CI8
9CIA
9CQ4
Enriched GO Terms of Interacting Partners
?
Lymphocyte Activation
Immune System Process
Leukocyte Activation
Cell Activation
Signal Transduction
Positive Regulation Of Immune System Process
Natural Killer Cell Activation
T Cell Activation
Regulation Of Lymphocyte Activation
Immune Response
Cell Surface Receptor Signaling Pathway
Regulation Of Cell Activation
Regulation Of Immune System Process
Immune Response-regulating Cell Surface Receptor Signaling Pathway
Regulation Of Immune Response
Regulation Of T Cell Activation
Positive Regulation Of Cell Activation
Immune Response-activating Cell Surface Receptor Signaling Pathway
Immune Response-regulating Signaling Pathway
Positive Regulation Of Lymphocyte Activation
Positive Regulation Of Immune Response
Antigen Receptor-mediated Signaling Pathway
Regulation Of Leukocyte Cell-cell Adhesion
Regulation Of Cell-cell Adhesion
Positive Regulation Of T Cell Activation
Immune Response-activating Signaling Pathway
Positive Regulation Of Leukocyte Cell-cell Adhesion
Plasma Membrane
T Cell Receptor Signaling Pathway
Activation Of Immune Response
Regulation Of Cell Adhesion
Lymphocyte Mediated Immunity
Positive Regulation Of Cell-cell Adhesion
Leukocyte Mediated Cytotoxicity
T Cell Costimulation
Phosphotyrosine Residue Binding
Regulation Of T Cell Receptor Signaling Pathway
Leukocyte Mediated Immunity
Immune Effector Process
Positive Regulation Of Cell Adhesion
Adaptive Immune Response
Regulation Of Mononuclear Cell Proliferation
Transmembrane Receptor Protein Tyrosine Kinase Adaptor Activity
T Cell Proliferation
Natural Killer Cell Mediated Cytotoxicity
Regulation Of Leukocyte Proliferation
Regulation Of Lymphocyte Mediated Immunity
T Cell Receptor Complex
Natural Killer Cell Mediated Immunity
Alpha-beta T Cell Receptor Complex
Cell Activation
Leukocyte Activation
Adaptive Immune Response
Lymphocyte Activation
Positive Regulation Of Natural Killer Cell Mediated Immunity
Positive Regulation Of Immune Response
Immune Response
Natural Killer Cell Activation
Regulation Of Natural Killer Cell Mediated Immunity
Platelet-derived Growth Factor Alpha-receptor Activity
Negative Regulation Of Microtubule Nucleation
Aconitate Hydratase Activity
Fc-gamma Receptor III Complex
Gamma-delta T Cell Receptor Complex
Immune Effector Process
Platelet-derived Growth Factor Receptor-alpha Signaling Pathway
Phospholipase C Activator Activity
Positive Regulation Of Cell Proliferation By VEGF-activated Platelet Derived Growth Factor Receptor Signaling Pathway
Metanephric Glomerular Capillary Formation
Platelet-derived Growth Factor Receptor-ligand Complex
TCR Signalosome
Tagcloud
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Tagcloud (Difference)
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Tagcloud (Intersection)
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