CD247 and PI4K2B

Number of citations of the paper that reports this interaction (PMID 16337488)
3

Data Source:
HPRD (in vitro, in vivo)

		CD247	PI4K2B
Gene Name		CD247 molecule	phosphatidylinositol 4-kinase type 2 beta
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Membrane T Cell Receptor Complex Alpha-beta T Cell Receptor Complex	Cytoplasm Cytosol Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity	1-phosphatidylinositol 4-kinase Activity ATP Binding
	Biological Process	Viral Process T Cell Costimulation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Regulation Of Defense Response To Virus By Virus Regulation Of Immune Response T Cell Receptor Signaling Pathway	Phospholipid Metabolic Process Phosphatidylinositol Biosynthetic Process Small Molecule Metabolic Process Phosphatidylinositol Phosphorylation
Pathways			Synthesis of PIPs at the plasma membrane Synthesis of PIPs at the early endosome membrane Synthesis of PIPs at the Golgi membrane Synthesis of PIPs at the ER membrane Metabolism of lipids and lipoproteins Phospholipid metabolism PI Metabolism
Drugs
Diseases
GWAS		Celiac disease ( 20190752) Celiac disease and Rheumatoid arthritis ( 21383967) Rheumatoid arthritis ( 20453842) Systemic sclerosis ( 21750679 20383147 21779181)
Protein-Protein Interactions		38 interactors: CD2 CD244 CD28 CD3D CD48 CD5 CSK DOCK2 FCGR3A FYN GAB2 GRB2 JAK3 LCK LY6E NCR1 NCR3 PCGF2 PI4K2B PTPN22 PTPN3 PTPN6 PTPRC SH2B3 SHC1 SLA SLA2 STAT5A STAT5B TFRC TIRAP TRA TRAT1 TRB UNC119 VTN ZAP70 ZNF281	4 interactors: AKT1 CASR CD247 MAPK14
Entrez ID		919	55300
HPRD ID		01729	15132
Ensembl ID		ENSG00000198821	ENSG00000038210
Uniprot IDs		P20963	G5E9Z4 Q8TCG2
PDB IDs		1TCE 1YGR 2HAC 2OQ1 3IK5 3IOZ
Enriched GO Terms of Interacting Partners?		Immune System Process Regulation Of Immune System Process Regulation Of Immune Response Regulation Of Cell Activation Positive Regulation Of Cell Activation Regulation Of Lymphocyte Activation Positive Regulation Of Immune System Process Regulation Of T Cell Activation Positive Regulation Of Immune Response Cell Activation Immune Response-regulating Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Cell-cell Adhesion Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Cell Adhesion Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Cell Adhesion Lymphocyte Activation Homotypic Cell-cell Adhesion Leukocyte Activation T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Hemopoiesis Defense Response Single Organismal Cell-cell Adhesion Leukocyte Cell-cell Adhesion Immune System Development Leukocyte Differentiation T Cell Receptor Signaling Pathway T Cell Costimulation Immune Response T Cell Differentiation Lymphocyte Differentiation Innate Immune Response Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway T Cell Differentiation In Thymus Positive Regulation Of Signal Transduction Organ Development Response To Stress Response To Stimulus Signal Transduction Regulation Of Body Fluid Levels Leukocyte Migration Cell Adhesion Positive Regulation Of Gamma-delta T Cell Differentiation	Positive Regulation Of Vasoconstriction Immune Response-regulating Signaling Pathway Positive Regulation Of Fat Cell Differentiation Regulation Of Vasoconstriction Response To Peptide Cellular Response To Growth Factor Stimulus T Cell Costimulation Response To Growth Factor Positive Regulation Of Reactive Oxygen Species Metabolic Process Regulation Of Establishment Of Protein Localization Cellular Response To Hypoxia Cellular Response To Decreased Oxygen Levels Vascular Endothelial Growth Factor Receptor Signaling Pathway Positive Regulation Of Transport Cellular Response To Oxygen Levels Peptidyl-serine Phosphorylation Stress-activated MAPK Cascade Regulation Of Protein Localization Stress-activated Protein Kinase Signaling Cascade Innate Immune Response Glycogen Cell Differentiation Involved In Embryonic Placenta Development P38MAPK Cascade Response To Organonitrogen Compound Regulation Of Fat Cell Differentiation Regulation Of Immune Response Glucose Metabolic Process Positive Regulation Of Immune System Process Regulation Of Reactive Oxygen Species Metabolic Process Apoptotic Process Programmed Cell Death Cell Surface Receptor Signaling Pathway Regulation Of Cellular Localization Cell Death Death Response To Abiotic Stimulus Platelet Activation Response To Fibroblast Growth Factor Positive Regulation Of Ion Transport Glucose Homeostasis Hexose Metabolic Process Positive Regulation Of T Cell Activation Response To Stress Neurotrophin TRK Receptor Signaling Pathway Positive Regulation Of Homotypic Cell-cell Adhesion Neurotrophin Signaling Pathway MAPK Cascade Striated Muscle Cell Differentiation Positive Regulation Of Intracellular Transport Negative Regulation Of Plasma Membrane Long-chain Fatty Acid Transport Negative Regulation Of Fatty Acid Beta-oxidation
Tagcloud ?		already annotation annotations autoimmunity b6 cd3 characteristically chip coding elements encode encodes encyclopedia enrich gencode intron manual marks project qrt quantification seq spatially supported t1d tcr throughput utilized wealth
Tagcloud (Difference) ?		already annotation annotations autoimmunity b6 cd3 characteristically chip coding elements encode encodes encyclopedia enrich gencode intron manual marks project qrt quantification seq spatially supported t1d tcr throughput utilized wealth
Tagcloud (Intersection) ?