CD244

Gene Name		CD244 molecule, natural killer cell receptor 2B4
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane
	Molecular Function	Receptor Activity Protein Binding
	Biological Process	Signal Transduction Blood Coagulation Leukocyte Migration
Pathways		Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233)
Protein-protein Interactions		5 interactors: ARHGEF7 CD247 CD48 LAT SH2D1B
Entrez ID		51744
HPRD ID		16121
Ensembl ID		ENSG00000122223
Uniprot IDs		Q9BZW8
PDB IDs
Enriched GO Terms of Interacting Partners?		Immune System Process Regulation Of Cell Adhesion Positive Regulation Of Immune Response T Cell Receptor Signaling Pathway Antigen Receptor-mediated Signaling Pathway Leukocyte Activation Involved In Immune Response Regulation Of Immune Response Positive Regulation Of Immune System Process Positive Regulation Of Lamellipodium Morphogenesis Fc Receptor Signaling Pathway Regulation Of Lamellipodium Morphogenesis Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response Regulation Of T Cell Activation Regulation Of Immune System Process Defense Response Positive Regulation Of Fibroblast Migration Regulation Of Cell-cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Regulation Of Lymphocyte Activation Blood Coagulation Hemostasis Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Positive Regulation Of Lamellipodium Organization Leukocyte Activation Positive Regulation Of Natural Killer Cell Mediated Immunity Response To Stimulus Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Defense Response To Virus By Virus Mast Cell Degranulation Regulation Of Body Fluid Levels Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Wound Healing Mast Cell Mediated Immunity Small GTPase Mediated Signal Transduction Focal Adhesion Assembly Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Fibroblast Migration Lysosome Localization Mast Cell Activation Cell Activation Response To Wounding Leukocyte Degranulation Lamellipodium Assembly Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Adherens Junction Assembly Lamellipodium Organization Negative Regulation Of ERBB Signaling Pathway
Tagcloud ?		accounting acpa aetiology apca apparently character citrullinated contradictory ctla4 deiminase drb1 genetics heritability histocompatibility hla incompletely interpreted mhc originated padi4 peptidylarginine ptpn22 ra rheumatoid stat4 subsets synovium update vital