CD244 and CD48

Number of citations of the paper that reports this interaction (PMID 11163399)
16

Data Source:
HPRD (in vitro, in vivo)

		CD244	CD48
Gene Name		CD244 molecule, natural killer cell receptor 2B4	CD48 molecule
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Plasma Membrane External Side Of Plasma Membrane Integral Component Of Membrane	Plasma Membrane Integral Component Of Plasma Membrane Membrane Anchored Component Of Membrane Membrane Raft Extracellular Vesicular Exosome
	Molecular Function	Receptor Activity Protein Binding	Receptor Activity Protein Binding
	Biological Process	Signal Transduction Blood Coagulation Leukocyte Migration	Defense Response Blood Coagulation Leukocyte Migration
Pathways		Cell surface interactions at the vascular wall	Cell surface interactions at the vascular wall
Drugs
Diseases
GWAS		Crohn's disease ( 21102463) Inflammatory bowel disease ( 23128233)	Inflammatory bowel disease ( 23128233)
Protein-Protein Interactions		5 interactors: ARHGEF7 CD247 CD48 LAT SH2D1B	10 interactors: BRIX1 CD2 CD244 CD247 EEF1D FYN GNAI3 IL18R1 IL18RAP LCK
Entrez ID		51744	962
HPRD ID		16121	00177
Ensembl ID		ENSG00000122223	ENSG00000117091
Uniprot IDs		Q9BZW8	P09326
PDB IDs			2EDO
Enriched GO Terms of Interacting Partners?		Immune System Process Regulation Of Cell Adhesion Positive Regulation Of Immune Response T Cell Receptor Signaling Pathway Antigen Receptor-mediated Signaling Pathway Leukocyte Activation Involved In Immune Response Regulation Of Immune Response Positive Regulation Of Immune System Process Positive Regulation Of Lamellipodium Morphogenesis Fc Receptor Signaling Pathway Regulation Of Lamellipodium Morphogenesis Immune Response-activating Cell Surface Receptor Signaling Pathway Immune Response Regulation Of T Cell Activation Regulation Of Immune System Process Defense Response Positive Regulation Of Fibroblast Migration Regulation Of Cell-cell Adhesion Immune Response-regulating Cell Surface Receptor Signaling Pathway Positive Regulation Of Cell Adhesion Regulation Of Lymphocyte Activation Blood Coagulation Hemostasis Immune Response-regulating Signaling Pathway Regulation Of Cell Activation Positive Regulation Of Lamellipodium Organization Leukocyte Activation Positive Regulation Of Natural Killer Cell Mediated Immunity Response To Stimulus Regulation Of Natural Killer Cell Mediated Immunity Regulation Of Defense Response To Virus By Virus Mast Cell Degranulation Regulation Of Body Fluid Levels Positive Regulation Of Substrate Adhesion-dependent Cell Spreading Wound Healing Mast Cell Mediated Immunity Small GTPase Mediated Signal Transduction Focal Adhesion Assembly Regulation Of Substrate Adhesion-dependent Cell Spreading Regulation Of Fibroblast Migration Lysosome Localization Mast Cell Activation Cell Activation Response To Wounding Leukocyte Degranulation Lamellipodium Assembly Negative Regulation Of Epidermal Growth Factor Receptor Signaling Pathway Adherens Junction Assembly Lamellipodium Organization Negative Regulation Of ERBB Signaling Pathway	Regulation Of Defense Response To Virus By Virus Blood Coagulation Hemostasis Leukocyte Migration Regulation Of Body Fluid Levels Wound Healing T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation T Cell Costimulation Cell Activation Regulation Of T Cell Activation Regulation Of Defense Response To Virus Positive Regulation Of Cell Activation Immune System Process Response To Wounding Leukocyte Cell-cell Adhesion Homotypic Cell-cell Adhesion Signal Transduction T Cell Receptor Signaling Pathway Regulation Of Cell-cell Adhesion Regulation Of Lymphocyte Activation Lymphocyte Activation Signaling Antigen Receptor-mediated Signaling Pathway Cell Communication Regulation Of Cell Activation Leukocyte Activation Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Single Organismal Cell-cell Adhesion Cell Surface Receptor Signaling Pathway Platelet Activation Cellular Response To Stimulus Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Regulation Of Cell Adhesion Regulation Of I-kappaB Kinase/NF-kappaB Signaling Immune Response Response To Stress Peptidyl-tyrosine Autophosphorylation Positive Regulation Of Cell-cell Adhesion Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Positive Regulation Of Interferon-gamma Production Positive Regulation Of Intracellular Signal Transduction Cell Migration Natural Killer Cell Activation Cell Motility Positive Regulation Of Immune System Process
Tagcloud ?		accounting acpa aetiology apca apparently character citrullinated contradictory ctla4 deiminase drb1 genetics heritability histocompatibility hla incompletely interpreted mhc originated padi4 peptidylarginine ptpn22 ra rheumatoid stat4 subsets synovium update vital	advance cd150 cdd committed doi effector epo epor erythroblasts erythrocytes erythroid erythropoiesis erythropoietin h2afy2 highlighted hscs immunophenotypically lin macroh2a2 mh2a2 november phospholipase plcgamma1 progenitors publication recapitulated sca1 stat5a tightly
Tagcloud (Difference) ?		accounting acpa aetiology apca apparently character citrullinated contradictory ctla4 deiminase drb1 genetics heritability histocompatibility hla incompletely interpreted mhc originated padi4 peptidylarginine ptpn22 ra rheumatoid stat4 subsets synovium update vital	advance cd150 cdd committed doi effector epo epor erythroblasts erythrocytes erythroid erythropoiesis erythropoietin h2afy2 highlighted hscs immunophenotypically lin macroh2a2 mh2a2 november phospholipase plcgamma1 progenitors publication recapitulated sca1 stat5a tightly
Tagcloud (Intersection) ?