CD247 and LY6E

Number of citations of the paper that reports this interaction (PMID 9575182)
6

Data Source:
HPRD (in vitro, in vivo)

		CD247	LY6E
Gene Name		CD247 molecule	lymphocyte antigen 6 complex, locus E
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Cytoplasm Plasma Membrane Integral Component Of Membrane T Cell Receptor Complex Alpha-beta T Cell Receptor Complex	Integral Component Of Plasma Membrane Anchored Component Of Membrane
	Molecular Function	Transmembrane Signaling Receptor Activity Protein Binding Identical Protein Binding Protein Homodimerization Activity
	Biological Process	Viral Process T Cell Costimulation Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Innate Immune Response Regulation Of Defense Response To Virus By Virus Regulation Of Immune Response T Cell Receptor Signaling Pathway	In Utero Embryonic Development Cell Surface Receptor Signaling Pathway Adrenal Gland Development Organ Growth Norepinephrine Metabolic Process Epinephrine Secretion Ventricular Cardiac Muscle Tissue Morphogenesis
Pathways
Drugs
Diseases
GWAS		Celiac disease ( 20190752) Celiac disease and Rheumatoid arthritis ( 21383967) Rheumatoid arthritis ( 20453842) Systemic sclerosis ( 21750679 20383147 21779181)
Protein-Protein Interactions		38 interactors: CD2 CD244 CD28 CD3D CD48 CD5 CSK DOCK2 FCGR3A FYN GAB2 GRB2 JAK3 LCK LY6E NCR1 NCR3 PCGF2 PI4K2B PTPN22 PTPN3 PTPN6 PTPRC SH2B3 SHC1 SLA SLA2 STAT5A STAT5B TFRC TIRAP TRA TRAT1 TRB UNC119 VTN ZAP70 ZNF281	2 interactors: CD247 FCGR2B
Entrez ID		919	4061
HPRD ID		01729	03227
Ensembl ID		ENSG00000198821	ENSG00000160932
Uniprot IDs		P20963	Q16553
PDB IDs		1TCE 1YGR 2HAC 2OQ1 3IK5 3IOZ
Enriched GO Terms of Interacting Partners?		Immune System Process Regulation Of Immune System Process Regulation Of Immune Response Regulation Of Cell Activation Positive Regulation Of Cell Activation Regulation Of Lymphocyte Activation Positive Regulation Of Immune System Process Regulation Of T Cell Activation Positive Regulation Of Immune Response Cell Activation Immune Response-regulating Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Regulation Of Cell-cell Adhesion Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Antigen Receptor-mediated Signaling Pathway Positive Regulation Of Cell Adhesion Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of Cell Adhesion Lymphocyte Activation Homotypic Cell-cell Adhesion Leukocyte Activation T Cell Aggregation T Cell Activation Lymphocyte Aggregation Leukocyte Aggregation Hemopoiesis Defense Response Single Organismal Cell-cell Adhesion Leukocyte Cell-cell Adhesion Immune System Development Leukocyte Differentiation T Cell Receptor Signaling Pathway T Cell Costimulation Immune Response T Cell Differentiation Lymphocyte Differentiation Innate Immune Response Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway T Cell Differentiation In Thymus Positive Regulation Of Signal Transduction Organ Development Response To Stress Response To Stimulus Signal Transduction Regulation Of Body Fluid Levels Leukocyte Migration Cell Adhesion Positive Regulation Of Gamma-delta T Cell Differentiation	Viral Process Regulation Of Immune Response Regulation Of Defense Response To Virus By Virus Immune Response Regulation Of Immune System Process T Cell Costimulation Regulation Of Defense Response To Virus Immune System Process T Cell Receptor Signaling Pathway Antigen Receptor-mediated Signaling Pathway Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Positive Regulation Of T Cell Activation Positive Regulation Of Homotypic Cell-cell Adhesion Positive Regulation Of Cell-cell Adhesion Phagocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Regulation Of T Cell Activation Positive Regulation Of Cell Activation
Tagcloud ?		already annotation annotations autoimmunity b6 cd3 characteristically chip coding elements encode encodes encyclopedia enrich gencode intron manual marks project qrt quantification seq spatially supported t1d tcr throughput utilized wealth
Tagcloud (Difference) ?		already annotation annotations autoimmunity b6 cd3 characteristically chip coding elements encode encodes encyclopedia enrich gencode intron manual marks project qrt quantification seq spatially supported t1d tcr throughput utilized wealth
Tagcloud (Intersection) ?