SFN and WDYHV1

Number of citations of the paper that reports this interaction (PMID 16189514)
699

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		SFN	WDYHV1
Gene Name		stratifin	WDYHV motif containing 1
Image
Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Cytosol Cytoplasmic Vesicle Membrane Extracellular Vesicular Exosome	Nucleus Cytosol
	Molecular Function	Protein Binding Protein Kinase C Inhibitor Activity Protein Kinase Binding Protein Domain Specific Binding Phosphoprotein Binding	Protein Binding Protein-N-terminal Glutamine Amidohydrolase Activity
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Release Of Cytochrome C From Mitochondria Keratinocyte Development Negative Regulation Of Protein Kinase Activity Apoptotic Process Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Epidermal Cell Division Negative Regulation Of Keratinocyte Proliferation Positive Regulation Of Cell Growth Keratinization Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Epidermal Cell Differentiation Positive Regulation Of Protein Export From Nucleus Membrane Organization Establishment Of Skin Barrier Negative Regulation Of Protein Serine/threonine Kinase Activity Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway	Cellular Protein Modification Process
Pathways		Activation of BAD and translocation to mitochondria Programmed Cell Death Translocation of GLUT4 to the plasma membrane Activation of BH3-only proteins Intrinsic Pathway for Apoptosis
Drugs
Diseases
GWAS
Protein-Protein Interactions		49 interactors: ABL1 BAD BAX BCR CCAR1 CCDC102B CCNH CDC25B CDK1 CHST1 EEF1A1 EGFR EIF2S1 EIF4B EXO1 FAM189A2 FAM53C FAM9B FOXO4 GPRIN2 HDAC5 HNRNPD ING1 KCNK15 KCNK3 KCNK9 KIAA0408 LONRF1 MAGEA1 MAP3K5 MARK3 MDM4 MKRN3 MST1R NR3C1 PLEKHF2 PLK4 RAB3IP RFFL RFWD2 SAMSN1 TBL3 TP53 TRIM25 TSC2 WDYHV1 YWHAG ZC2HC1C ZFP36	88 interactors: ACTB ACTG1 AMOT AMOTL2 APIP ASL BIRC2 BLMH BLOC1S6 C1orf50 CAPN3 CBFA2T2 CCDC102B CCDC184 CDA CDR2 COIL CRYAA CTH DAB1 DCTPP1 DHPS EDARADD EIF2B1 ETV6 FTH1 GAS7 GMDS GNMT GOLGA2 HPRT1 HSD17B14 JUP KCNH1 KCTD1 KLHL12 KRT31 KRTAP10-5 KRTAP10-7 KRTAP4-2 KRTAP5-9 KRTAP9-2 KRTAP9-4 LONRF1 LZTFL1 LZTS2 MAGEA11 MARCH10 MDFI MIF MTUS2 NCOA5 NECAB2 NME1 NPL NT5C1A NUDT14 PCBD1 PNMA1 PNMA5 PPCDC PRMT1 PRPS2 PTS PYGM RABAC1 RAD54L RBBP8 RBPMS RPIA SEPT3 SFN SIAH1 SMN1 STX11 THAP1 TMEM239 TNR TOLLIP TRIM27 TRIM54 TRIP13 TSC22D1 VAC14 VCP XIAP ZBTB8A ZNF341
Entrez ID		2810	55093
HPRD ID		03185	07653
Ensembl ID		ENSG00000175793	ENSG00000156795
Uniprot IDs		P31947	Q96HA8
PDB IDs		1YWT 1YZ5 3IQJ 3IQU 3IQV 3LW1 3MHR 3O8I 3P1N 3P1O 3P1P 3P1Q 3P1R 3P1S 3SMK 3SML 3SMM 3SMN 3SMO 3SPR 3T0L 3T0M 3U9X 3UX0 4DAT 4DAU 4DHM 4DHN 4DHO 4DHP 4DHQ 4DHR 4DHS 4DHT 4DHU 4FR3 4HQW 4HRU 4IEA 4JC3 4JDD	3C9Q
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Positive Regulation Of Neuron Death Cell Cycle Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Metabolic Process Regulation Of Phosphorylation Cellular Response To Organic Substance Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Kinase Activity Cellular Response To Organonitrogen Compound Regulation Of Phosphorus Metabolic Process Cell Cycle Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Intracellular Transport Mitotic Cell Cycle Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Intracellular Signal Transduction ERBB Signaling Pathway Regulation Of Protein Kinase Activity Response To Stress Mitotic Cell Cycle Positive Regulation Of Cell Cycle Response To Organic Substance Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Cell Cycle Positive Regulation Of Protein Metabolic Process Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Catalytic Activity Cellular Response To Insulin Stimulus G2/M Transition Of Mitotic Cell Cycle Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Mitotic Cell Cycle Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Mitochondrion Organization Immune Response-regulating Cell Surface Receptor Signaling Pathway Response To Hormone Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Regulation Of Intracellular Signal Transduction Cellular Response To Hormone Stimulus Regulation Of Cell Proliferation B Cell Activation Fc Receptor Signaling Pathway	Protein Oligomerization Protein Complex Assembly Protein Homooligomerization Cellular Component Assembly Protein Homotetramerization Protein Tetramerization Nucleobase-containing Small Molecule Metabolic Process Nucleoside Metabolic Process Catabolic Process Cellular Nitrogen Compound Metabolic Process Purine Nucleoside Metabolic Process Anatomical Structure Development Small Molecule Metabolic Process Developmental Process Biosynthetic Process Cell Differentiation Nitrogen Compound Metabolic Process Regulation Of Cellular Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Regulation Of Apoptotic Process Cellular Metabolic Process Purine Nucleoside Monophosphate Catabolic Process Regulation Of Cell Death Tetrahydrobiopterin Biosynthetic Process Cell Development Nucleotide Metabolic Process System Development Inhibition Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Protein Ubiquitination Sulfur Amino Acid Metabolic Process Multicellular Organismal Development Aromatic Compound Catabolic Process Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Protein Modification By Small Protein Conjugation Cofactor Metabolic Process Regulation Of Nucleotide-binding Oligomerization Domain Containing Signaling Pathway Neuron Projection Development Regulation Of Metabolic Process Organophosphate Metabolic Process Cellular Modified Amino Acid Metabolic Process Regulation Of Cellular Localization Membrane Organization Response To Stimulus Organophosphate Catabolic Process Double-strand Break Repair Cellular Process S-adenosylmethionine Metabolic Process Pyrimidine Nucleoside Metabolic Process
Tagcloud ?		aging alarm amplitude auditory circuits cortico elderly electrophysiologically employed false finding frontal impairments latency limbic memory n4 p3 perform position potentials prefrontal recency serial sternberg subjects task working young
Tagcloud (Difference) ?		aging alarm amplitude auditory circuits cortico elderly electrophysiologically employed false finding frontal impairments latency limbic memory n4 p3 perform position potentials prefrontal recency serial sternberg subjects task working young
Tagcloud (Intersection) ?