SFN and HNRNPD

Number of citations of the paper that reports this interaction (PMID 16902409)
19

Data Source:
BioGRID (pull down, affinity chromatography technology)
HPRD (in vitro, in vivo)

		SFN	HNRNPD
Gene Name		stratifin	heterogeneous nuclear ribonucleoprotein D (AU-rich element RNA binding protein 1, 37kDa)
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Gene Ontology Annotations	Cellular Component	Extracellular Space Nucleus Cytoplasm Cytosol Cytoplasmic Vesicle Membrane Extracellular Vesicular Exosome	Nucleus Nucleoplasm Cytosol Ribonucleoprotein Complex Extracellular Vesicular Exosome
	Molecular Function	Protein Binding Protein Kinase C Inhibitor Activity Protein Kinase Binding Protein Domain Specific Binding Phosphoprotein Binding	Nucleotide Binding RNA Binding Protein Binding Telomeric DNA Binding Poly(A) RNA Binding
	Biological Process	Regulation Of Cyclin-dependent Protein Serine/threonine Kinase Activity Release Of Cytochrome C From Mitochondria Keratinocyte Development Negative Regulation Of Protein Kinase Activity Apoptotic Process Signal Transduction Intrinsic Apoptotic Signaling Pathway In Response To DNA Damage Regulation Of Epidermal Cell Division Negative Regulation Of Keratinocyte Proliferation Positive Regulation Of Cell Growth Keratinization Negative Regulation Of Cysteine-type Endopeptidase Activity Involved In Apoptotic Process Positive Regulation Of Epidermal Cell Differentiation Positive Regulation Of Protein Export From Nucleus Membrane Organization Establishment Of Skin Barrier Negative Regulation Of Protein Serine/threonine Kinase Activity Intrinsic Apoptotic Signaling Pathway Positive Regulation Of Protein Insertion Into Mitochondrial Membrane Involved In Apoptotic Signaling Pathway	MRNA Splicing, Via Spliceosome Transcription, DNA-templated Regulation Of Transcription, DNA-templated RNA Processing RNA Catabolic Process RNA Splicing Gene Expression Regulation Of Circadian Rhythm Regulation Of MRNA Stability Positive Regulation Of Translation Positive Regulation Of Transcription, DNA-templated Circadian Regulation Of Translation
Pathways		Activation of BAD and translocation to mitochondria Programmed Cell Death Translocation of GLUT4 to the plasma membrane Activation of BH3-only proteins Intrinsic Pathway for Apoptosis	Processing of Capped Intron-Containing Pre-mRNA mRNA Splicing mRNA Splicing - Major Pathway
Drugs
Diseases
GWAS
Protein-Protein Interactions		49 interactors: ABL1 BAD BAX BCR CCAR1 CCDC102B CCNH CDC25B CDK1 CHST1 EEF1A1 EGFR EIF2S1 EIF4B EXO1 FAM189A2 FAM53C FAM9B FOXO4 GPRIN2 HDAC5 HNRNPD ING1 KCNK15 KCNK3 KCNK9 KIAA0408 LONRF1 MAGEA1 MAP3K5 MARK3 MDM4 MKRN3 MST1R NR3C1 PLEKHF2 PLK4 RAB3IP RFFL RFWD2 SAMSN1 TBL3 TP53 TRIM25 TSC2 WDYHV1 YWHAG ZC2HC1C ZFP36	92 interactors: ABCC10 ACTB ARF4 B3GAT3 BCL2 BET1L BRCA1 C1QBP CAPN1 CD81 CD97 CINP COG7 COL18A1 CSDE1 CTSB CUTA DGCR2 DHX30 EEF2 EIF4G1 ERG EXOSC4 FBXL15 FLNA GSK3B GTF3C3 GTSE1 GUK1 HBZ HDAC1 HIRA HMGA1 HNRNPC HNRNPF HNRNPH3 HNRNPK HNRNPU HSPA4 HSPB1 HSPB2 IGF2BP2 IL7R IMMP2L IMMT ING4 LDHA LSM5 MAP2K1 MAPK6 MEOX2 MPP1 MTA2 MYC NTMT1 P4HB PABPC1 PCBP1 PCBP2 PCSK7 PDLIM7 PEX10 PPOX PRDX3 PRKACA PTBP2 PYCR1 RALY RPSA SAFB SDF2 SEPT9 SF3B4 SFN SHISA5 SLC27A5 SLC3A2 SNAPC4 SNRPC SREK1 SUMO4 SYNCRIP TMEM261 TNPO1 TRN-GTT2-1 TSEN34 U2AF2 UBE2I UQCRC1 VEGFA VHL YBX1
Entrez ID		2810	3184
HPRD ID		03185	03206
Ensembl ID		ENSG00000175793
Uniprot IDs		P31947	Q14103
PDB IDs		1YWT 1YZ5 3IQJ 3IQU 3IQV 3LW1 3MHR 3O8I 3P1N 3P1O 3P1P 3P1Q 3P1R 3P1S 3SMK 3SML 3SMM 3SMN 3SMO 3SPR 3T0L 3T0M 3U9X 3UX0 4DAT 4DAU 4DHM 4DHN 4DHO 4DHP 4DHQ 4DHR 4DHS 4DHT 4DHU 4FR3 4HQW 4HRU 4IEA 4JC3 4JDD	1HD0 1HD1 1IQT 1WTB 1X0F 2Z5N
Enriched GO Terms of Interacting Partners?		Regulation Of Protein Metabolic Process Regulation Of Cellular Protein Metabolic Process Regulation Of Cell Cycle Positive Regulation Of Neuron Death Cell Cycle Regulation Of Protein Phosphorylation Positive Regulation Of Cellular Metabolic Process Regulation Of Phosphorylation Cellular Response To Organic Substance Regulation Of Metabolic Process Positive Regulation Of Metabolic Process Regulation Of Kinase Activity Cellular Response To Organonitrogen Compound Regulation Of Phosphorus Metabolic Process Cell Cycle Process Positive Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Positive Regulation Of Intracellular Transport Mitotic Cell Cycle Process Positive Regulation Of Cellular Protein Metabolic Process Regulation Of Mitochondrial Outer Membrane Permeabilization Involved In Apoptotic Signaling Pathway Epidermal Growth Factor Receptor Signaling Pathway Intracellular Signal Transduction ERBB Signaling Pathway Regulation Of Protein Kinase Activity Response To Stress Mitotic Cell Cycle Positive Regulation Of Cell Cycle Response To Organic Substance Intrinsic Apoptotic Signaling Pathway Negative Regulation Of Cell Cycle Positive Regulation Of Protein Metabolic Process Cellular Response To Stress Cellular Response To DNA Damage Stimulus Regulation Of Catalytic Activity Cellular Response To Insulin Stimulus G2/M Transition Of Mitotic Cell Cycle Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Negative Regulation Of Mitotic Cell Cycle Enzyme Linked Receptor Protein Signaling Pathway Positive Regulation Of Mitochondrion Organization Immune Response-regulating Cell Surface Receptor Signaling Pathway Response To Hormone Mitotic Cell Cycle Phase Transition Cell Cycle Phase Transition Regulation Of Mitotic Cell Cycle Regulation Of Intracellular Signal Transduction Cellular Response To Hormone Stimulus Regulation Of Cell Proliferation B Cell Activation Fc Receptor Signaling Pathway	MRNA Metabolic Process RNA Splicing MRNA Processing RNA Processing MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Heterocycle Metabolic Process Cellular Metabolic Process Gene Expression Cellular Aromatic Compound Metabolic Process Cellular Nitrogen Compound Metabolic Process Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process RNA Metabolic Process Posttranscriptional Regulation Of Gene Expression Metabolic Process MRNA Stabilization Response To Stress Negative Regulation Of Cellular Metabolic Process Regulation Of Gene Expression CRD-mediated MRNA Stabilization Cellular Process Positive Regulation Of Gene Expression Negative Regulation Of Biosynthetic Process Regulation Of MRNA Stability Regulation Of RNA Stability Positive Regulation Of Cellular Biosynthetic Process Negative Regulation Of Gene Expression Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Cell Death Positive Regulation Of Protein Export From Nucleus Nuclear-transcribed MRNA Catabolic Process Regulation Of Apoptotic Process MRNA Catabolic Process Viral Process Vascular Endothelial Growth Factor Receptor Signaling Pathway Regulation Of RNA Splicing Positive Regulation Of Cellular Metabolic Process Nuclear-transcribed MRNA Catabolic Process, Deadenylation-dependent Decay Organelle Organization Regulation Of Metabolic Process Response To Wounding Positive Regulation Of Blood Vessel Endothelial Cell Migration Negative Regulation Of Cell Death RNA Catabolic Process Negative Regulation Of RNA Splicing Chromatin Remodeling Positive Regulation Of Metabolic Process Positive Regulation Of Mitochondrion Organization Regulation Of Translation
Tagcloud ?		aging alarm amplitude auditory circuits cortico elderly electrophysiologically employed false finding frontal impairments latency limbic memory n4 p3 perform position potentials prefrontal recency serial sternberg subjects task working young	abcb7 advance alas2 asxl1 bclaf1 brca1 causal cbl cd34 december deregulation disruption doi erythroid exon leu link online pathophysiology prpf8 publication rars refractory sf3b1 sideroblasts slc25a37 splicing transcript transcriptome
Tagcloud (Difference) ?		aging alarm amplitude auditory circuits cortico elderly electrophysiologically employed false finding frontal impairments latency limbic memory n4 p3 perform position potentials prefrontal recency serial sternberg subjects task working young	abcb7 advance alas2 asxl1 bclaf1 brca1 causal cbl cd34 december deregulation disruption doi erythroid exon leu link online pathophysiology prpf8 publication rars refractory sf3b1 sideroblasts slc25a37 splicing transcript transcriptome
Tagcloud (Intersection) ?