ELP3 and ELP1

Number of citations of the paper that reports this interaction (PubMedID 36617428)
102

Data Source:
BioGRID (affinity chromatography technology, biochemical, pull down)

		ELP3	ELP1
Description		elongator acetyltransferase complex subunit 3	elongator acetyltransferase complex subunit 1
Image
GO Annotations	Cellular Component	Nucleus Nucleolus Cytoplasm Cytosol Elongator Holoenzyme Complex	Nucleus Cytoplasm Cytosol Elongator Holoenzyme Complex
	Molecular Function	TRNA Binding RNA Binding Catalytic Activity Protein Binding Phosphorylase Kinase Regulator Activity Acetyltransferase Activity Transferase Activity Acyltransferase Activity Acyltransferase Activity, Transferring Groups Other Than Amino-acyl Groups Metal Ion Binding Iron-sulfur Cluster Binding 4 Iron, 4 Sulfur Cluster Binding TRNA Uridine(34) Acetyltransferase Activity	TRNA Binding Protein Binding
	Biological Process	Neuron Migration TRNA Wobble Uridine Modification TRNA Wobble Base 5-methoxycarbonylmethyl-2-thiouridinylation Regulation Of Transcription By RNA Polymerase II Regulation Of Translation Nervous System Development Central Nervous System Development TRNA Processing Positive Regulation Of Cell Migration	TRNA Wobble Uridine Modification TRNA Wobble Base 5-methoxycarbonylmethyl-2-thiouridinylation Regulation Of Translation TRNA Processing
Pathways		HATs acetylate histones	HATs acetylate histones
Drugs
Diseases
GWAS		Adult body size ( 32376654) Body mass index ( 28892062) Body size at age 10 ( 32376654) Childhood body mass index ( 26604143 33045005) Malaria ( 31844061) Systemic lupus erythematosus ( 28714469)	Appendicular lean mass ( 33097823)
Interacting Genes		8 interacting genes: CTDP1 ELP1 ELP6 H3C14 H4C1 MYC SMAD1 SMURF1	27 interacting genes: BAG6 BARD1 CCT5 CDKN2B CHUK CSTF2 ELP2 ELP3 ELP6 HTT IKBKB IRF4 MAN2A2 MAP3K14 MAP3K7 MAPK8 MRPL42 NDUFB9 NFKBIA NIPSNAP3A PBX2 PLP2 SDHAF2 SNAPIN TAC3 TTR TXNDC9
Entrez ID		55140	8518
HPRD ID		10936	04763
Ensembl ID		ENSG00000134014	ENSG00000070061
Uniprot IDs		B4DKA4 B4DXV1 Q9H9T3	A0A6Q8PGW3 A0A6Q8PHA0 B3KNB2 B4E3I9 F5H2T0 O95163 Q8N516
PDB IDs		8PTX 8PTY 8PTZ 8PU0	5CQR 8PTX 8PTY 8PTZ 8PU0
Enriched GO Terms of Interacting Partners?		Elongator Holoenzyme Complex TRNA Wobble Uridine Modification TRNA Modification RNA Metabolic Process I-SMAD Binding TRNA Processing RNA Modification TRNA Metabolic Process Nucleic Acid Metabolic Process Regulation Of Primary Metabolic Process Regulation Of Multicellular Organismal Development Positive Regulation Of MiRNA Metabolic Process Intracellular Iron Ion Homeostasis Protein-containing Complex Negative Regulation Of Cell Differentiation Macromolecule Metabolic Process Positive Regulation Of MiRNA Transcription Macromolecule Biosynthetic Process Regulation Of Cell Differentiation Positive Regulation Of Metanephric Cap Mesenchymal Cell Proliferation Acinar Cell Proliferation Positive Regulation Of Acinar Cell Proliferation SCF Ubiquitin Ligase Complex Binding Inflammasome-mediated Signaling Pathway Engulfment Of Target By Autophagosome Nucleobase-containing Compound Metabolic Process Negative Regulation Of Muscle Cell Differentiation RNA Processing Regulation Of MiRNA Transcription Regulation Of Macromolecule Metabolic Process Nucleoplasm BMP Signaling Pathway Structural Constituent Of Chromatin Negative Regulation Of Developmental Process Homomeric SMAD Protein Complex Regulation Of MiRNA Metabolic Process Negative Regulation Of Myeloid Cell Differentiation Myc-Max Complex Regulation Of Acinar Cell Proliferation Regulation Of Translation TFIIF-class Transcription Factor Complex Binding Regulation Of Metabolic Process Mesodermal Cell Fate Commitment Osteoblast Fate Commitment NK T Cell Proliferation Nucleosome Assembly TRNA Wobble Base 5-methoxycarbonylmethyl-2-thiouridinylation Phosphorylase Kinase Regulator Activity Homeostasis Of Number Of Retina Cells Nucleosome	Non-canonical NF-kappaB Signal Transduction Elongator Holoenzyme Complex TRNA Wobble Uridine Modification Immune Response-regulating Signaling Pathway Canonical NF-kappaB Signal Transduction Immune Response-regulating Cell Surface Receptor Signaling Pathway Innate Immune Response Activating Cell Surface Receptor Signaling Pathway Pattern Recognition Receptor Signaling Pathway IkappaB Kinase Activity Fc-epsilon Receptor Signaling Pathway Stress-activated MAPK Cascade Innate Immune Response-activating Signaling Pathway Stress-activated Protein Kinase Signaling Cascade Interleukin-1-mediated Signaling Pathway Cellular Response To Tumor Necrosis Factor Activation Of Innate Immune Response Immune Response-activating Signaling Pathway Cytoplasmic Pattern Recognition Receptor Signaling Pathway Signal Transduction Involved In Regulation Of Gene Expression Response To Tumor Necrosis Factor Immune Response-activating Cell Surface Receptor Signaling Pathway Toll-like Receptor 4 Signaling Pathway Activation Of Immune Response Cell Surface Toll-like Receptor Signaling Pathway IkappaB Kinase Complex Negative Regulation Of Cytokine Production Involved In Inflammatory Response Regulation Of Innate Immune Response Regulation Of Immune Response Cell Surface Pattern Recognition Receptor Signaling Pathway Fc Receptor Signaling Pathway Positive Regulation Of Innate Immune Response Tumor Necrosis Factor-mediated Signaling Pathway CD40 Receptor Complex Transferrin Receptor Binding TRIF-dependent Toll-like Receptor Signaling Pathway Cytosol Scaffold Protein Binding MyD88-independent Toll-like Receptor Signaling Pathway Toll-like Receptor 3 Signaling Pathway MyD88-dependent Toll-like Receptor Signaling Pathway MAP Kinase Activity Regulation Of Cytokine Production Involved In Inflammatory Response TRNA Modification Protein Serine/threonine Kinase Activity Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Cytokine-mediated Signaling Pathway Intracellular Receptor Signaling Pathway Positive Regulation Of Immune Response Cellular Response To Lectin Stimulatory C-type Lectin Receptor Signaling Pathway
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?