CBFA2T2 and MAGEA6

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		CBFA2T2	MAGEA6
Description		CBFA2/RUNX1 partner transcriptional co-repressor 2	MAGE family member A6
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus Nucleoplasm	Nucleus
	Molecular Function	Transcription Corepressor Activity Protein Binding Zinc Ion Binding Metal Ion Binding	Protein Binding Histone Deacetylase Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II DNA-templated Transcription Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Epithelial Cell Differentiation Negative Regulation Of Notch Signaling Pathway Negative Regulation Of DNA-templated Transcription Intestinal Epithelial Cell Differentiation	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Autophagy
Pathways		Specification of primordial germ cells
Drugs
Diseases
GWAS		Height ( 28552196) Hip circumference adjusted for BMI ( 34021172) Triglyceride levels ( 32203549)	Serum alkaline phosphatase levels ( 33339817)
Interacting Genes		34 interacting genes: APP ATN1 ATXN1L BAG4 CBFA2T3 CBFB CEP83 FBXL19 GTF2E1 ID3 KIFC3 KRTAP13-2 LBP MAGEA6 MDFI NCOR1 NCOR2 NEUROG1 NOTCH3 NTAQ1 PDP1 PEX14 PHAF1 PRDM6 RERE RUNX1 SIKE1 SIN3A SORBS3 TAL2 TCF4 TCP1 ZC2HC1A ZNF652	75 interacting genes: ACOT7 ACTN3 AKAP9 ANKRD26P1 APOA4 ARFIP1 ATOSA ATP6V1G1 ATPAF2 BCL7B BET1 BFSP2 BOLA3 C1orf216 CAMTA2 CBFA2T2 CCDC146 CCDC185 CCDC187 CCDC24 COL4A6 CTF1 DLGAP3 DLGAP4 DNTTIP1 ELMOD3 EXOC5 FRMPD1 GADD45GIP1 GCSH GFOD1 HAUS1 HLA-DRB4 HNRNPM IQUB KIF27 KLHL38 LCORL LIN37 LIN52 LSM2 MCM7 MCRS1 MED21 MID2 MIPOL1 MORN3 MSGN1 NCK2 NOSTRIN PCBD2 PDE4D PRKAA1 RASSF10 RASSF4 RCOR3 REX1BD RPL37A RUSC1 S100A14 S100A9 SH2D4A SMARCD1 SNAP47 SNX4 SON STAMBPL1 STX5 TRIM26 TRIM28 TSPYL6 TULP3 TXNDC9 XRCC4 ZNF76
Entrez ID		9139	4105
HPRD ID		04721	02168
Ensembl ID		ENSG00000078699	ENSG00000197172
Uniprot IDs		O43439	P43360
PDB IDs
Enriched GO Terms of Interacting Partners?		Negative Regulation Of RNA Metabolic Process Negative Regulation Of RNA Biosynthetic Process Negative Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of DNA-templated Transcription Regulation Of Nucleobase-containing Compound Metabolic Process Negative Regulation Of Transcription By RNA Polymerase II Regulation Of RNA Metabolic Process Regulation Of DNA-templated Transcription Regulation Of RNA Biosynthetic Process Transcription Corepressor Activity Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Macromolecule Biosynthetic Process Negative Regulation Of Biosynthetic Process Negative Regulation Of Macromolecule Metabolic Process Regulation Of Primary Metabolic Process Negative Regulation Of Metabolic Process Regulation Of Macromolecule Biosynthetic Process Regulation Of Macromolecule Metabolic Process Regulation Of Metabolic Process Regulation Of Gene Expression Core-binding Factor Complex Regulation Of MiRNA Transcription Negative Regulation Of MiRNA Transcription Regulation Of MiRNA Metabolic Process Positive Regulation Of Neuron Differentiation Regulation Of Neuron Differentiation Positive Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Transcription Regulator Inhibitor Activity Nucleus Histone Deacetylase Complex Regulation Of CD8-positive, Alpha-beta T Cell Differentiation Positive Regulation Of CD8-positive, Alpha-beta T Cell Activation Regulation Of Glycolytic Process Regulation Of Carbohydrate Catabolic Process Protein Binding Transcription Repressor Complex Chromatin Binding Protein Dimerization Activity Regulation Of ATP Metabolic Process DNA Binding Negative Regulation Of Androgen Receptor Signaling Pathway Cellular Response To Catecholamine Stimulus Regulation Of Purine Nucleotide Metabolic Process Response To Catecholamine Neuron Differentiation Regulation Of CD8-positive, Alpha-beta T Cell Activation Negative Regulation Of Glycolytic Process Negative Regulation Of CD4-positive, Alpha-beta T Cell Differentiation Negative Regulation Of ATP Metabolic Process Amyloid-beta Complex	Protein Binding SNARE Complex Suppression Of Viral Release By Host
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