CBFA2T2 and ID3

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		CBFA2T2	ID3
Gene Name		core-binding factor, runt domain, alpha subunit 2; translocated to, 2	inhibitor of DNA binding 3, dominant negative helix-loop-helix protein
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Nucleoplasm Cytoplasm Microtubule Cytoskeleton
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding	Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Transcription Factor Binding Protein Domain Specific Binding Protein Dimerization Activity
	Biological Process	Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Epithelial Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter	Negative Regulation Of Transcription From RNA Polymerase II Promoter Metanephros Development Regulation Of DNA Replication Transcription, DNA-templated Multicellular Organismal Development Central Nervous System Development Heart Development Muscle Organ Development Circadian Rhythm Response To Wounding Neuron Differentiation Epithelial Cell Differentiation Notochord Development Odontogenesis Positive Regulation Of Apoptotic Process Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Myoblast Differentiation Negative Regulation Of Osteoblast Differentiation Negative Regulation Of Transcription, DNA-templated Regulation Of Cell Cycle
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: APP ATN1 ATXN1L CBFA2T3 CBFB FBXL19 GTF2E1 ID3 LBP MDFI NCOR1 NCOR2 NEUROG1 NOTCH3 PDP1 PRDM14 RERE RUNX1 SIN3A TAL2 TCP1 WDYHV1 ZNF652	36 interactors: ADD1 ATF3 CBFA2T2 CDK2 CNOT3 CSK E2F4 ELK1 ELK4 FAM74A1 FHL2 GATA4 GNB2 GTF2A1L HES1 ID4 IFI16 IKBKG MLX MYF5 MYF6 MYOD1 MYOG PAX5 PRDM14 PUF60 RND1 RUNX1T1 SAP30 SREBF1 TCF12 TCF3 TCF4 ZNF3 ZNF408 ZNF626
Entrez ID		9139	3399
HPRD ID		04721	02608
Ensembl ID		ENSG00000078699	ENSG00000117318
Uniprot IDs		O43439	Q02535
PDB IDs			2LFH
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Multicellular Organismal Development Nitrogen Compound Metabolic Process Biosynthetic Process Organ Development Definitive Hemopoiesis Central Nervous System Development Developmental Process System Development Anatomical Structure Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Notch Signaling Pathway Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Cell Differentiation Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Regulation Of Cellular Process Negative Regulation Of Cell Differentiation Forebrain Development DNA-templated Transcription, Initiation Metabolic Process Embryo Development Negative Regulation Of Cellular Metabolic Process Myeloid Cell Differentiation Thalamus Development In Utero Embryonic Development Nervous System Development Positive Regulation Of Mitotic Cell Cycle	Transcription, DNA-templated RNA Biosynthetic Process Cellular Macromolecule Biosynthetic Process RNA Metabolic Process Macromolecule Biosynthetic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Gene Expression Regulation Of Nitrogen Compound Metabolic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Nucleobase-containing Compound Metabolic Process Positive Regulation Of Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Biosynthetic Process Positive Regulation Of Transcription From RNA Polymerase II Promoter Cellular Nitrogen Compound Metabolic Process Transcription From RNA Polymerase II Promoter Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Gene Expression Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Regulation Of Metabolic Process Nitrogen Compound Metabolic Process Positive Regulation Of Cellular Metabolic Process Muscle Structure Development Skeletal Muscle Cell Differentiation Positive Regulation Of Metabolic Process Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Developmental Process Regulation Of Cellular Process Positive Regulation Of Skeletal Muscle Fiber Development Cellular Metabolic Process Negative Regulation Of Biosynthetic Process Cell Fate Commitment Negative Regulation Of Transcription From RNA Polymerase II Promoter Striated Muscle Tissue Development Multicellular Organismal Development Muscle Cell Differentiation Muscle Tissue Development Negative Regulation Of Cellular Metabolic Process Skeletal Muscle Tissue Development Skeletal Muscle Organ Development Organ Development
Tagcloud ?			accumulating associates box compartment competition constitute developmentally e2a e47 enforced erythroid gal helix heterodimers hypermethylation implicates k562 lineages lymphoid metazoa overlapping shift specificities strict suggestive tal1 vicinity vp16
Tagcloud (Difference) ?			accumulating associates box compartment competition constitute developmentally e2a e47 enforced erythroid gal helix heterodimers hypermethylation implicates k562 lineages lymphoid metazoa overlapping shift specificities strict suggestive tal1 vicinity vp16
Tagcloud (Intersection) ?