CBFA2T2 and RERE

Number of citations of the paper that reports this interaction (PMID 16713569)
214

Data Source:
BioGRID (two hybrid)
HPRD (two hybrid)

		CBFA2T2	RERE
Gene Name		core-binding factor, runt domain, alpha subunit 2; translocated to, 2	arginine-glutamic acid dipeptide (RE) repeats
Image		No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Histone Deacetylase Complex Nucleus
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding	Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Binding Poly-glutamine Tract Binding Zinc Ion Binding Sequence-specific DNA Binding
	Biological Process	Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Epithelial Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter	Chromatin Remodeling Transcription, DNA-templated Regulation Of Transcription, DNA-templated NLS-bearing Protein Import Into Nucleus Multicellular Organismal Development
Pathways
Drugs
Diseases
GWAS			Autism spectrum disorder, attention deficit-hyperactivity disorder, bipolar disorder, major depressive disorder, and schizophrenia (combined) ( 23453885) Bone mineral density ( 22504420) Vertical cup-disc ratio ( 20548946) Vitiligo ( 20410501)
Protein-Protein Interactions		23 interactors: APP ATN1 ATXN1L CBFA2T3 CBFB FBXL19 GTF2E1 ID3 LBP MDFI NCOR1 NCOR2 NEUROG1 NOTCH3 PDP1 PRDM14 RERE RUNX1 SIN3A TAL2 TCP1 WDYHV1 ZNF652	20 interactors: ALG13 ATN1 CBFA2T2 ECM1 EFEMP1 EFEMP2 EHMT2 HIST2H3C KAT6A KRTAP4-12 LZTR1 NR2E1 PLSCR1 PRRC2A PRRC2B PSMA3 RBFOX2 TRIM22 TRIP6 ZMYND8
Entrez ID		9139	473
HPRD ID		04721	05566
Ensembl ID		ENSG00000078699	ENSG00000142599
Uniprot IDs		O43439	B1AKN3 Q9P2R6
PDB IDs			2YQK
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Multicellular Organismal Development Nitrogen Compound Metabolic Process Biosynthetic Process Organ Development Definitive Hemopoiesis Central Nervous System Development Developmental Process System Development Anatomical Structure Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Notch Signaling Pathway Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Cell Differentiation Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Regulation Of Cellular Process Negative Regulation Of Cell Differentiation Forebrain Development DNA-templated Transcription, Initiation Metabolic Process Embryo Development Negative Regulation Of Cellular Metabolic Process Myeloid Cell Differentiation Thalamus Development In Utero Embryonic Development Nervous System Development Positive Regulation Of Mitotic Cell Cycle	Regulation Of Nitrogen Compound Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of Cellular Metabolic Process Negative Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Negative Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Negative Regulation Of Biosynthetic Process Regulation Of Gene Expression Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Gene Expression Regulation Of Metabolic Process Gene Expression DNA Methylation On Cytosine Cellular Nitrogen Compound Metabolic Process Regulation Of Cellular Process Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of I-kappaB Kinase/NF-kappaB Signaling Nitrogen Compound Metabolic Process Nucleobase-containing Compound Metabolic Process Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of I-kappaB Kinase/NF-kappaB Signaling Transcription, DNA-templated RNA Biosynthetic Process Amygdala Development RNA Metabolic Process DNA Methylation Somatic Stem Cell Maintenance Response To Stress Negative Regulation Of Cell Differentiation Cellular Macromolecule Biosynthetic Process DNA Modification Negative Regulation Of Transcription From RNA Polymerase II Promoter Macromolecule Biosynthetic Process Extracellular Matrix Organization Extracellular Structure Organization Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity DNA Methylation On Cytosine Within A CG Sequence Blood Coagulation Hemostasis Radial Glia Guided Migration Of Purkinje Cell Regulation Of Definitive Erythrocyte Differentiation Release Of Cytoplasmic Sequestered NF-kappaB Positive Regulation Of Angiogenesis Regulation Of Cell Differentiation Peptidyl-amino Acid Modification Phosphatidylserine Biosynthetic Process Regulation Of Timing Of Neuron Differentiation
Tagcloud ?			antagonism caudal downregulating e8 ectopic embryos exiting extending fgf fgf8 fused h3k27me3 lacz mesoderm neuroectoderm polycomb prc2 ra raldh2 rarb rare rares repress represses repressive somite somites trunk vertebrate
Tagcloud (Difference) ?			antagonism caudal downregulating e8 ectopic embryos exiting extending fgf fgf8 fused h3k27me3 lacz mesoderm neuroectoderm polycomb prc2 ra raldh2 rarb rare rares repress represses repressive somite somites trunk vertebrate
Tagcloud (Intersection) ?