CBFA2T2 and NEUROG1

Number of citations of the paper that reports this interaction (PMID 20211142)
148

Data Source:
BioGRID (two hybrid)

		CBFA2T2	NEUROG1
Gene Name		core-binding factor, runt domain, alpha subunit 2; translocated to, 2	neurogenin 1
Image		No pdb structure	No pdb structure
Gene Ontology Annotations	Cellular Component	Nucleus	Nucleus Perikaryon
	Molecular Function	Sequence-specific DNA Binding Transcription Factor Activity Transcription Corepressor Activity Protein Binding Metal Ion Binding	Transcription Factor Binding Transcription Factor Activity DNA Binding Chromatin Binding Sequence-specific DNA Binding Transcription Factor Activity Protein Dimerization Activity E-box Binding
	Biological Process	Positive Regulation Of Neuron Projection Development Negative Regulation Of Neuron Projection Development Epithelial Cell Differentiation Negative Regulation Of Transcription, DNA-templated Positive Regulation Of Transcription From RNA Polymerase II Promoter	Transcription, DNA-templated Regulation Of Transcription From RNA Polymerase II Promoter Nervous System Development Neuron Differentiation Positive Regulation Of Exit From Mitosis Inner Ear Morphogenesis Cell Fate Commitment Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Positive Regulation Of Sequence-specific DNA Binding Transcription Factor Activity
Pathways
Drugs
Diseases
GWAS
Protein-Protein Interactions		23 interactors: APP ATN1 ATXN1L CBFA2T3 CBFB FBXL19 GTF2E1 ID3 LBP MDFI NCOR1 NCOR2 NEUROG1 NOTCH3 PDP1 PRDM14 RERE RUNX1 SIN3A TAL2 TCP1 WDYHV1 ZNF652	6 interactors: CBFA2T2 CREBBP RUNX1T1 SMAD1 TARBP2 TCF4
Entrez ID		9139	4762
HPRD ID		04721	03430
Ensembl ID		ENSG00000078699	ENSG00000181965
Uniprot IDs		O43439	F1T0H3 Q92886
PDB IDs
Enriched GO Terms of Interacting Partners?		Transcription, DNA-templated RNA Biosynthetic Process RNA Metabolic Process Gene Expression Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Cellular Macromolecule Biosynthetic Process Macromolecule Biosynthetic Process Nucleobase-containing Compound Metabolic Process Regulation Of Transcription From RNA Polymerase II Promoter Heterocycle Metabolic Process Cellular Aromatic Compound Metabolic Process Regulation Of Metabolic Process Cellular Nitrogen Compound Metabolic Process Cellular Metabolic Process Multicellular Organismal Development Nitrogen Compound Metabolic Process Biosynthetic Process Organ Development Definitive Hemopoiesis Central Nervous System Development Developmental Process System Development Anatomical Structure Development Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Notch Signaling Pathway Transcription From RNA Polymerase II Promoter Negative Regulation Of Gene Expression Cell Differentiation Transcription Initiation From RNA Polymerase II Promoter Negative Regulation Of Biosynthetic Process Regulation Of Cellular Process Negative Regulation Of Cell Differentiation Forebrain Development DNA-templated Transcription, Initiation Metabolic Process Embryo Development Negative Regulation Of Cellular Metabolic Process Myeloid Cell Differentiation Thalamus Development In Utero Embryonic Development Nervous System Development Positive Regulation Of Mitotic Cell Cycle	Negative Regulation Of Gene Expression Production Of MiRNAs Involved In Gene Silencing By MiRNA Regulation Of Transcription From RNA Polymerase II Promoter Gene Silencing By MiRNA Cellular Response To DsRNA Posttranscriptional Gene Silencing Negative Regulation Of Cellular Metabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Regulation Of RNA Biosynthetic Process Regulation Of RNA Metabolic Process Positive Regulation Of Neuron Differentiation Positive Regulation Of Transcription From RNA Polymerase II Promoter Negative Regulation Of Transcription, DNA-templated Negative Regulation Of Nucleic Acid-templated Transcription Negative Regulation Of RNA Biosynthetic Process Regulation Of Gene Expression Regulation Of Nitrogen Compound Metabolic Process Gene Silencing By RNA Positive Regulation Of Neurogenesis Response To DsRNA Positive Regulation Of Transcription, DNA-templated Negative Regulation Of Biosynthetic Process Positive Regulation Of Cell Development Positive Regulation Of Macromolecule Biosynthetic Process Regulation Of Neuron Differentiation Positive Regulation Of Gene Expression RNA Metabolic Process Gene Silencing Regulation Of Cell Differentiation Positive Regulation Of Cellular Biosynthetic Process Cell Differentiation Cellular Macromolecular Complex Assembly Gene Expression Embryonic Morphogenesis Fat Cell Differentiation Regulation Of Neurogenesis MiRNA Loading Onto RISC Involved In Gene Silencing By MiRNA Canonical Wnt Signaling Pathway Involved In Positive Regulation Of Epithelial To Mesenchymal Transition Catenin Import Into Nucleus Cellular Component Assembly Negative Regulation Of Cell Differentiation Stem Cell Maintenance Transcription Initiation From RNA Polymerase II Promoter Positive Regulation Of Cell Morphogenesis Involved In Differentiation Positive Regulation Of Heparan Sulfate Proteoglycan Biosynthetic Process Targeting Of MRNA For Destruction Involved In RNA Interference N-terminal Peptidyl-lysine Acetylation Regulation Of Cell Development Positive Regulation Of Cell Differentiation
Tagcloud ?			appearance comprehending correlate epigenetic epigenetics etc foxg1 grik3 hand2 hox integrating islands luad methylated nkx6 pik3ca pik3r3 pou4f2 prkcb ptgdr raf1 rap1a refers stages subnetwork tlx3 ubc ultimate wise
Tagcloud (Difference) ?			appearance comprehending correlate epigenetic epigenetics etc foxg1 grik3 hand2 hox integrating islands luad methylated nkx6 pik3ca pik3r3 pou4f2 prkcb ptgdr raf1 rap1a refers stages subnetwork tlx3 ubc ultimate wise
Tagcloud (Intersection) ?