MAGEA6 and CAMTA2

Number of citations of the paper that reports this interaction (PubMedID 32296183)
50

Data Source:
BioGRID (two hybrid)

		MAGEA6	CAMTA2
Description		MAGE family member A6	calmodulin binding transcription activator 2
Image		No pdb structure	No pdb structure
GO Annotations	Cellular Component	Nucleus	Chromatin Nucleus
	Molecular Function	Protein Binding Histone Deacetylase Binding	DNA Binding Chromatin Binding Double-stranded DNA Binding Transcription Coregulator Activity Transcription Coactivator Activity Protein Binding Histone Deacetylase Binding Sequence-specific DNA Binding
	Biological Process	Negative Regulation Of Transcription By RNA Polymerase II Negative Regulation Of Autophagy	Regulation Of Transcription By RNA Polymerase II Cardiac Muscle Hypertrophy In Response To Stress Positive Regulation Of Transcription By RNA Polymerase II
Pathways
Drugs
Diseases
GWAS		Serum alkaline phosphatase levels ( 33339817)	Intraocular pressure ( 29617998) Keratoconus ( 33649486)
Interacting Genes		75 interacting genes: ACOT7 ACTN3 AKAP9 ANKRD26P1 APOA4 ARFIP1 ATOSA ATP6V1G1 ATPAF2 BCL7B BET1 BFSP2 BOLA3 C1orf216 CAMTA2 CBFA2T2 CCDC146 CCDC185 CCDC187 CCDC24 COL4A6 CTF1 DLGAP3 DLGAP4 DNTTIP1 ELMOD3 EXOC5 FRMPD1 GADD45GIP1 GCSH GFOD1 HAUS1 HLA-DRB4 HNRNPM IQUB KIF27 KLHL38 LCORL LIN37 LIN52 LSM2 MCM7 MCRS1 MED21 MID2 MIPOL1 MORN3 MSGN1 NCK2 NOSTRIN PCBD2 PDE4D PRKAA1 RASSF10 RASSF4 RCOR3 REX1BD RPL37A RUSC1 S100A14 S100A9 SH2D4A SMARCD1 SNAP47 SNX4 SON STAMBPL1 STX5 TRIM26 TRIM28 TSPYL6 TULP3 TXNDC9 XRCC4 ZNF76	8 interacting genes: CALM1 CALM2 CALM3 HDAC5 MAGEA6 MEMO1 NKX2-5 ZNF483
Entrez ID		4105	23125
HPRD ID		02168	13002
Ensembl ID		ENSG00000197172	ENSG00000108509
Uniprot IDs		P43360	I3L3W6 O94983
PDB IDs
Enriched GO Terms of Interacting Partners?		Protein Binding SNARE Complex Suppression Of Viral Release By Host	Transporter Inhibitor Activity Negative Regulation Of Calcium Ion Export Across Plasma Membrane Regulation Of Calcium Ion Export Across Plasma Membrane Adenylate Cyclase Activator Activity Regulation Of Cell Communication By Electrical Coupling Involved In Cardiac Conduction Titin Binding Detection Of Calcium Ion Regulation Of Cardiac Muscle Contraction Regulation Of Cell Communication By Electrical Coupling Protein Phosphatase Activator Activity Calyx Of Held Regulation Of Striated Muscle Contraction Catalytic Complex Regulation Of Cardiac Muscle Contraction By Regulation Of The Release Of Sequestered Calcium Ion Negative Regulation Of Transporter Activity Negative Regulation Of High Voltage-gated Calcium Channel Activity Calcium Channel Complex Negative Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Calcineurin-mediated Signaling Presynaptic Cytosol Myelin Sheath Regulation Of Cardiac Muscle Contraction By Calcium Ion Signaling Regulation Of Release Of Sequestered Calcium Ion Into Cytosol By Sarcoplasmic Reticulum Negative Regulation Of Calcium Ion Transmembrane Transport Regulation Of Muscle Contraction Spindle Microtubule Presynaptic Endocytosis Substantia Nigra Development Calcium Channel Regulator Activity Regulation Of Heart Contraction Sperm Midpiece Negative Regulation Of Calcium Ion Transport G2/M Transition Of Mitotic Cell Cycle Long-term Synaptic Potentiation Regulation Of Ryanodine-sensitive Calcium-release Channel Activity Sarcomere Cell Cycle G2/M Phase Transition Neural Nucleus Development Negative Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Muscle System Process Regulation Of Blood Circulation Negative Regulation Of Cation Transmembrane Transport Protein Serine/threonine Kinase Activator Activity Positive Regulation Of Sequestering Of Calcium Ion Negative Regulation Of Monoatomic Ion Transmembrane Transport Voltage-gated Potassium Channel Complex Negative Regulation Of Voltage-gated Calcium Channel Activity Calcium-dependent Protein Binding Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Monoatomic Ion Transmembrane Transporter Activity
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