MAGEA6 and NCK2

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		MAGEA6	NCK2
Gene Name		melanoma antigen family A, 6	NCK adaptor protein 2
Image
Gene Ontology Annotations	Cellular Component	Cellular_component	Cytoplasm Endoplasmic Reticulum Cytosol Vesicle Membrane
	Molecular Function	Molecular_function Protein Binding	SH3/SH2 Adaptor Activity Protein Binding Cytoskeletal Adaptor Activity Receptor Signaling Complex Scaffold Activity
	Biological Process	Biological_process	Regulation Of Translation Actin Filament Organization Signal Transduction Signal Complex Assembly Epidermal Growth Factor Receptor Signaling Pathway Regulation Of Epidermal Growth Factor-activated Receptor Activity Axon Guidance Negative Regulation Of Cell Proliferation Positive Regulation Of Signal Transduction Cell Migration Lamellipodium Assembly Positive Regulation Of Actin Filament Polymerization Negative Regulation Of Peptidyl-serine Phosphorylation Positive Regulation Of T Cell Proliferation T Cell Activation Positive Regulation Of Transcription From RNA Polymerase II Promoter Vascular Endothelial Growth Factor Receptor Signaling Pathway Ephrin Receptor Signaling Pathway Regulation Of Endoplasmic Reticulum Stress-induced EIF2 Alpha Phosphorylation
Pathways			Signaling by PDGF Ephrin signaling Axon guidance Activation of Rac Signaling by VEGF Downstream signal transduction EPH-Ephrin signaling Nephrin interactions Signaling by Robo receptor VEGFA-VEGFR2 Pathway
Drugs
Diseases
GWAS			Addiction ( 23533358)
Protein-Protein Interactions		37 interactors: ACOT7 AKAP9 ANKRD26P1 ATP6V1G1 ATPAF2 BCL7B BET1 CCDC146 CTF1 ELMOD3 EXOC5 FAM214A FRMPD1 GFOD1 HAUS1 HLA-DRB4 IQUB KLHL38 LCORL LIN37 LSM2 MIPOL1 MORN3 NCK2 PDE4D RASSF4 RCOR3 RPL37A S100A14 SH2D4A SNAP47 SNX4 STAMBPL1 STX5 TRIM28 TULP3 TXNDC9	80 interactors: ABI1 ABI2 ABI3 ARHGAP32 ATN1 AXIN1 AXL BCL11A CBLB CCDC33 CD3E CHN1 CPSF6 CPSF7 DDR1 DNM1 DOCK1 DOK1 DRAP1 DVL1 EEF1G EFHC2 EFNB1 EFNB2 EGFR EIF3H ERBB2 ERBB3 FAM53C FASLG FCRL2 FGFR1 FXR2 HNRNPK HOMEZ HOXC4 ILK IRS1 KHDRBS1 KIAA1217 LCP2 LIMS1 LNX1 LRRIQ3 LZTS2 MAGEA6 MASP1 MEOX2 NCKIPSD NPHS1 NR5A1 NTRK2 PAK1 PDGFRB PKN2 PRR20A PSMD10 PTK2 RASSF7 RBM26 REL SF3B4 SORBS2 SOS1 SPRY2 SRPK1 SRPK2 SYNPO TCF4 TNR TRIM27 TRIM41 TRIP6 VARS2 VPS37B WAS WASL WBP11 WIPF2 ZBTB7B
Entrez ID		4105	8440
HPRD ID		02168	05378
Ensembl ID		ENSG00000197172	ENSG00000071051
Uniprot IDs		P43357 P43360	E7ERP6 O43639
PDB IDs		1QEW	1U5S 1WX6 1Z3K 2B86 2CIA 2FRW 2FRY 2JXB 4E6R
Enriched GO Terms of Interacting Partners?		Vesicle Fusion Vesicle Fusion With Golgi Apparatus Organelle Fusion Vesicle Organization Regulation Of Peptidyl-serine Phosphorylation Negative Regulation Of Peptidyl-serine Phosphorylation Membrane Fusion Cellular Protein Complex Assembly Protein Complex Assembly Palmitic Acid Biosynthetic Process Medium-chain Fatty-acyl-CoA Catabolic Process Long-chain Fatty-acyl-CoA Catabolic Process Adrenergic Receptor Signaling Pathway Involved In Positive Regulation Of Heart Rate	Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Fc Receptor Signaling Pathway Enzyme Linked Receptor Protein Signaling Pathway Immune Response-regulating Cell Surface Receptor Signaling Pathway Innate Immune Response Signal Transduction Positive Regulation Of Signal Transduction Immune Response-regulating Signaling Pathway Signaling Movement Of Cell Or Subcellular Component Cell Communication Immune Response Locomotion Regulation Of Immune Response Regulation Of Immune System Process Cell Surface Receptor Signaling Pathway Defense Response Peptidyl-tyrosine Phosphorylation Axon Guidance Intracellular Signal Transduction Cell Migration Positive Regulation Of Intracellular Signal Transduction Cellular Response To Stimulus Anatomical Structure Development Positive Regulation Of Protein Metabolic Process Cell Development Gene Expression Regulation Of Cellular Process Immune System Process Cell Motility System Development Anatomical Structure Morphogenesis Regulation Of Cell Proliferation Multicellular Organismal Development Chemotaxis Cell Morphogenesis Involved In Differentiation Axonogenesis Regulation Of Protein Metabolic Process Neuron Projection Morphogenesis Regulation Of Metabolic Process Cell Differentiation Positive Regulation Of Metabolic Process Axon Development Developmental Process Response To Stimulus Epidermal Growth Factor Receptor Signaling Pathway ERBB Signaling Pathway Neurogenesis Cell Morphogenesis Involved In Neuron Differentiation Neuron Projection Development
Tagcloud ?		aberrations accrued arid1a arid2 axon beauty cdkn2a epc1 exome guidance informative integrative map2k4 mll3 nalcn reaffirming recapitulated recurrently robo sf3b1 slc16a4 sleeping slit smad4 supportive tgfbr2 transposon uncover zim2	accumulates adapter atr becoming cleavage coordination cytoskeletal depleted depletion discrete hela hyperactive increasingly interconnectedness interconnectivity irradiation monitored mostly nck1 parp phenocopies redundant shortly socs7 strikingly translocation undergo uv
Tagcloud (Difference) ?		aberrations accrued arid1a arid2 axon beauty cdkn2a epc1 exome guidance informative integrative map2k4 mll3 nalcn reaffirming recapitulated recurrently robo sf3b1 slc16a4 sleeping slit smad4 supportive tgfbr2 transposon uncover zim2	accumulates adapter atr becoming cleavage coordination cytoskeletal depleted depletion discrete hela hyperactive increasingly interconnectedness interconnectivity irradiation monitored mostly nck1 parp phenocopies redundant shortly socs7 strikingly translocation undergo uv
Tagcloud (Intersection) ?