PSTPIP1 and SYCE1

Number of citations of the paper that reports this interaction (PubMedID 26871637)
43

Data Source:
BioGRID (two hybrid)

		PSTPIP1	SYCE1
Description		proline-serine-threonine phosphatase interacting protein 1	synaptonemal complex central element protein 1
Image			No pdb structure
GO Annotations	Cellular Component	Uropod Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane Lamellipodium Cleavage Furrow Cell Projection Perinuclear Region Of Cytoplasm	Synaptonemal Complex Central Element Nucleus Chromosome
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding
	Biological Process	Immune System Process Endocytosis Inflammatory Response Cell Adhesion Signal Transduction Innate Immune Response	Synaptonemal Complex Assembly Cell Division Meiotic Cell Cycle Synaptonemal Complex Organization
Pathways		The NLRP3 inflammasome Purinergic signaling in leishmaniasis infection	Meiotic synapsis
Drugs
Diseases		Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome
GWAS		Hip circumference adjusted for BMI ( 34021172) Neurofibrillary tangles ( 31497858) Neutrophil count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		64 interacting genes: ABL1 AXIN1 BUB3 CCDC172 CD2 CD2AP CHD4 CWF19L2 DHX40 DNM2 EHHADH EXOC5 FAM90A1 FASLG FBXL18 HAPLN2 HHEX HMG20A HSF2BP IL16 KANK2 KHDRBS1 LIN37 LSM4 MCRS1 MEFV MOS MVP NAV2 NCBP1 PCDHB14 PNKP PRPF31 PRR35 PTPN12 PTPN18 RINT1 RNPS1 RPL9 RTP5 RXRB SCNM1 SDCBP SH2D4A SHBG SMARCD1 SPG7 SYCE1 TFIP11 TPH1 TRAF3IP3 TSGA10IP TTC1 TULP3 UBE2W WAS WASF1 WASF2 WASL ZC2HC1C ZNF175 ZNF408 ZNF580 ZNF688	45 interacting genes: ALOX5 ARNT2 BEX2 BFSP2 CBY2 CCDC102B CCHCR1 CFAP100 CINP CNN1 EDRF1 EXOC8 FAM161A FAM161B HAUS1 HMG20B HSPB1 HSPB7 IQUB KAT5 KIFC3 KRT18 MBD3 MPV17 MRFAP1L1 NME7 PSTPIP1 RALBP1 RBCK1 RUNX1T1 SCNM1 SKA1 SMARCE1 SPATC1L SSX2 STX19 TFIP11 TPM3 TRAF1 TRIM41 TSG101 TXN2 VPS25 WASHC3 ZNF124
Entrez ID		9051	93426
HPRD ID		05891	12598
Ensembl ID		ENSG00000140368	ENSG00000171772
Uniprot IDs		A0A0S2Z5P3 J3KPG6 O43586	A0A0B4J1R9 Q8N0S2
PDB IDs		2DIL 7AAL 7AAM 7AAN
Enriched GO Terms of Interacting Partners?		Actin Filament Polymerization Protein Polymerization MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Actin Polymerization Or Depolymerization SH3 Domain Binding Negative Regulation Of Membrane Tubulation Protein Binding Regulation Of Plasma Membrane Organization MRNA Processing RNA Splicing MRNA Metabolic Process Regulation Of ERBB Signaling Pathway Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Spliceosomal Tri-snRNP Complex Regulation Of Double-strand Break Repair Regulation Of DNA Repair Negative Regulation Of ERBB Signaling Pathway Lamellipodium Morphogenesis Negative Regulation Of Cellular Component Organization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin Filament Organization Podosome Regulation Of Vitamin D Receptor Signaling Pathway Substrate-dependent Cell Migration, Cell Extension Spliceosomal Complex Actin Cytoskeleton Ruffle SCAR Complex	Cytoskeleton
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?