PSTPIP1 and FBXL18

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PSTPIP1	FBXL18
Gene Name		proline-serine-threonine phosphatase interacting protein 1	F-box and leucine-rich repeat protein 18
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Uropod Actomyosin Contractile Ring Cytosol Membrane Lamellipodium Cleavage Furrow Perinuclear Region Of Cytoplasm
	Molecular Function	Actin Binding Protein Binding Protein Phosphatase Binding
	Biological Process	Endocytosis Inflammatory Response Cell Adhesion Signal Transduction Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Innate Immune Response
Pathways		The NLRP3 inflammasome Inflammasomes Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		29 interactors: ABL1 BUB3 CD2 CD2AP DNM2 FAM90A1 FASLG FBXL18 KHDRBS1 LSM4 MEFV MVP PCDHB14 PRPF31 PTPN12 PTPN18 RTP5 SDCBP SH2D4A SHBG SPG7 TRAF3IP3 TULP3 UBE2W WAS WASF1 WASF2 WASL ZNF175	21 interactors: CALCOCO2 FHL3 GOLGA2 HNRNPK KRT40 KRTAP10-3 KRTAP4-12 MDFI MID2 MTUS2 NOTCH2NL PLSCR1 PNMA1 PSMA3 PSTPIP1 RBPMS TFCP2 TRAF1 TRAF4 WWP1 WWP2
Entrez ID		9051	80028
HPRD ID		05891	07753
Ensembl ID		ENSG00000140368	ENSG00000155034
Uniprot IDs		O43586	F5H4Z4 Q96ME1
PDB IDs		2DIL
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Negative Regulation Of Membrane Tubulation Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Actin Cytoskeleton Organization Regulation Of Actin Nucleation Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Positive Regulation Of Interferon-gamma Secretion Regulation Of Cytoskeleton Organization Movement Of Cell Or Subcellular Component Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Actin Cytoskeleton Organization Actin Filament-based Movement Actin Filament-based Process Mitotic Cell Cycle Process Substrate-dependent Cell Migration, Cell Extension Cellular Component Assembly Regulation Of Oxidoreductase Activity Regulation Of Cellular Component Organization Mitotic Cell Cycle Signaling Actin Polymerization Or Depolymerization Cytoskeleton Organization Cell Communication Phagocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Immune System Process Signal Transduction Rac Protein Signal Transduction Cell Projection Assembly Actin Filament Organization Mitotic Nuclear Division Nitric Oxide Metabolic Process Regulation Of Catalytic Activity Reactive Nitrogen Species Metabolic Process Endocytosis Cell Cycle Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Endothelial Cell Apoptotic Process Cellular Response To Stimulus Cell Surface Receptor Signaling Pathway Substrate-dependent Cell Migration Organelle Organization Positive Regulation Of Organelle Organization Regulation Of Nitric-oxide Synthase Activity	Viral Process Protein Ubiquitination Protein Modification By Small Protein Conjugation Viral Entry Into Host Cell Entry Into Host Cell Regulation Of Nitrogen Compound Metabolic Process Proteasome-mediated Ubiquitin-dependent Protein Catabolic Process Regulation Of Binding Proteasomal Protein Catabolic Process Protein Ubiquitination Involved In Ubiquitin-dependent Protein Catabolic Process Regulation Of Transcription, DNA-templated Regulation Of Nucleic Acid-templated Transcription Positive Regulation Of Protein Metabolic Process Regulation Of RNA Biosynthetic Process Negative Regulation Of Viral Process Positive Regulation Of Signal Transduction Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Regulation Of RNA Metabolic Process Regulation Of Lipid Transport By Positive Regulation Of Transcription From RNA Polymerase II Promoter Regulation Of Signal Transduction Defense Response Positive Regulation Of DNA Topoisomerase (ATP-hydrolyzing) Activity Negative Regulation Of Binding Response To Stimulus Interaction With Host Immune System Process Positive Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Regulation Of Gene Expression Positive Regulation Of JNK Cascade Positive Regulation Of Protein Modification Process Inflammatory Response Regulation Of Signaling Positive Regulation Of NF-kappaB Transcription Factor Activity Positive Regulation Of Stress-activated MAPK Cascade Positive Regulation Of Stress-activated Protein Kinase Signaling Cascade Apoptotic Process Phosphatidylserine Biosynthetic Process Regulation Of Metabolic Process Programmed Cell Death Ubiquitin-dependent Protein Catabolic Process Regulation Of Protein Binding Modification-dependent Protein Catabolic Process Regulation Of Viral Process Cell Death Regulation Of Low-density Lipoprotein Particle Receptor Biosynthetic Process Protein Localization To Microtubule Death Regulation Of JNK Cascade Regulation Of Cellular Process Proteolysis Involved In Cellular Protein Catabolic Process
Tagcloud ?		adipocyte biologically chick chicken chickens cutoff experimentally klf5 lpin1 luciferase map3k7 mettl14 microrna mir miranda mirna pck2 pdcd5 pycr2 slc2a2 splenocytes tardbp tnfsf10 transcriptionally tumourigenesis ube2e3 ubiquitously utrs vertebrate
Tagcloud (Difference) ?		adipocyte biologically chick chicken chickens cutoff experimentally klf5 lpin1 luciferase map3k7 mettl14 microrna mir miranda mirna pck2 pdcd5 pycr2 slc2a2 splenocytes tardbp tnfsf10 transcriptionally tumourigenesis ube2e3 ubiquitously utrs vertebrate
Tagcloud (Intersection) ?