PSTPIP1 and RTP5

Number of citations of the paper that reports this interaction (PubMedID 25416956)
56

Data Source:
BioGRID (two hybrid, two hybrid)

		PSTPIP1	RTP5
Description		proline-serine-threonine phosphatase interacting protein 1	receptor transporter protein 5 (putative)
Image			No pdb structure
GO Annotations	Cellular Component	Uropod Cytoplasm Cytosol Cytoskeleton Plasma Membrane Membrane Lamellipodium Cleavage Furrow Cell Projection Perinuclear Region Of Cytoplasm	Membrane
	Molecular Function	Protein Binding Identical Protein Binding	Protein Binding Zinc Ion Binding Olfactory Receptor Binding Metal Ion Binding
	Biological Process	Immune System Process Endocytosis Inflammatory Response Cell Adhesion Signal Transduction Innate Immune Response	Detection Of Chemical Stimulus Involved In Sensory Perception Of Bitter Taste Protein Targeting To Membrane Protein Insertion Into Membrane
Pathways		The NLRP3 inflammasome Purinergic signaling in leishmaniasis infection
Drugs
Diseases		Pyogenic sterile arthritis, pyoderma gangrenosum, and acne (PAPA) syndrome
GWAS		Hip circumference adjusted for BMI ( 34021172) Neurofibrillary tangles ( 31497858) Neutrophil count ( 32888494) White blood cell count ( 32888494)
Interacting Genes		64 interacting genes: ABL1 AXIN1 BUB3 CCDC172 CD2 CD2AP CHD4 CWF19L2 DHX40 DNM2 EHHADH EXOC5 FAM90A1 FASLG FBXL18 HAPLN2 HHEX HMG20A HSF2BP IL16 KANK2 KHDRBS1 LIN37 LSM4 MCRS1 MEFV MOS MVP NAV2 NCBP1 PCDHB14 PNKP PRPF31 PRR35 PTPN12 PTPN18 RINT1 RNPS1 RPL9 RTP5 RXRB SCNM1 SDCBP SH2D4A SHBG SMARCD1 SPG7 SYCE1 TFIP11 TPH1 TRAF3IP3 TSGA10IP TTC1 TULP3 UBE2W WAS WASF1 WASF2 WASL ZC2HC1C ZNF175 ZNF408 ZNF580 ZNF688	51 interacting genes: ACTN2 ACTN3 AKAP8L APOC1 ASPG BEND5 BPIFA1 CALCOCO2 CARD9 CBY2 CIDEB COG6 DOCK8 EIF3F FGF14 GOLGA2 GOLGA6L9 HNRNPK HSF2BP KIFAP3 KRT27 KRT31 KRT33B KRT34 KRT40 KRT86 KRTAP19-5 KRTAP6-2 LZTS2 MDFI MIPOL1 MIS18A MKRN3 MTUS2 NFKBID PDE4DIP PNMA1 PNMA2 PSMA3 PSMA6 PSTPIP1 RBPMS RINT1 ROPN1 SERTAD3 SP100 SPDL1 TRAF1 TRIM23 TSGA10 USHBP1
Entrez ID		9051	285093
HPRD ID		05891	08159
Ensembl ID		ENSG00000140368	ENSG00000188011
Uniprot IDs		A0A0S2Z5P3 J3KPG6 O43586	Q14D33
PDB IDs		2DIL 7AAL 7AAM 7AAN
Enriched GO Terms of Interacting Partners?		Actin Filament Polymerization Protein Polymerization MRNA Splicing, Via Spliceosome RNA Splicing, Via Transesterification Reactions Actin Polymerization Or Depolymerization SH3 Domain Binding Negative Regulation Of Membrane Tubulation Protein Binding Regulation Of Plasma Membrane Organization MRNA Processing RNA Splicing MRNA Metabolic Process Regulation Of ERBB Signaling Pathway Regulation Of Double-strand Break Repair Via Nonhomologous End Joining Spliceosomal Tri-snRNP Complex Regulation Of Double-strand Break Repair Regulation Of DNA Repair Negative Regulation Of ERBB Signaling Pathway Lamellipodium Morphogenesis Negative Regulation Of Cellular Component Organization Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Actin Filament Organization Podosome Regulation Of Vitamin D Receptor Signaling Pathway Substrate-dependent Cell Migration, Cell Extension Spliceosomal Complex Actin Cytoskeleton Ruffle SCAR Complex	Intermediate Filament Structural Constituent Of Skin Epidermis Intermediate Filament Organization Identical Protein Binding Intermediate Filament Cytoskeleton Organization Keratin Filament Intermediate Filament-based Process Protein Binding Cytoskeleton Organization Organelle Organization Cytoskeleton Structural Molecule Activity Proteasome Core Complex, Alpha-subunit Complex Very-low-density Lipoprotein Particle Assembly
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