PSTPIP1 and TRAF3IP3

Number of citations of the paper that reports this interaction (PMID 25416956)
0

Data Source:
BioGRID (two hybrid)

		PSTPIP1	TRAF3IP3
Gene Name		proline-serine-threonine phosphatase interacting protein 1	TRAF3 interacting protein 3
Image			No pdb structure
Gene Ontology Annotations	Cellular Component	Stress Fiber Uropod Actomyosin Contractile Ring Cytosol Membrane Lamellipodium Cleavage Furrow Perinuclear Region Of Cytoplasm	Integral Component Of Membrane
	Molecular Function	Actin Binding Protein Binding Protein Phosphatase Binding	Protein Binding
	Biological Process	Endocytosis Inflammatory Response Cell Adhesion Signal Transduction Nucleotide-binding Domain, Leucine Rich Repeat Containing Receptor Signaling Pathway Innate Immune Response
Pathways		The NLRP3 inflammasome Inflammasomes Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways Innate Immune System
Drugs
Diseases
GWAS
Protein-Protein Interactions		29 interactors: ABL1 BUB3 CD2 CD2AP DNM2 FAM90A1 FASLG FBXL18 KHDRBS1 LSM4 MEFV MVP PCDHB14 PRPF31 PTPN12 PTPN18 RTP5 SDCBP SH2D4A SHBG SPG7 TRAF3IP3 TULP3 UBE2W WAS WASF1 WASF2 WASL ZNF175	12 interactors: CCDC155 CDCA7L EMD FATE1 NDEL1 PSTPIP1 SP100 SSSCA1 TFIP11 TRAF3 TRIM36 WAC
Entrez ID		9051	80342
HPRD ID		05891	16305
Ensembl ID		ENSG00000140368	ENSG00000009790
Uniprot IDs		O43586	Q9Y228
PDB IDs		2DIL
Enriched GO Terms of Interacting Partners?		Positive Regulation Of Arp2/3 Complex-mediated Actin Nucleation Positive Regulation Of Actin Nucleation Negative Regulation Of Membrane Tubulation Regulation Of Arp2/3 Complex-mediated Actin Nucleation Regulation Of Actin Cytoskeleton Organization Regulation Of Actin Nucleation Regulation Of Organelle Organization Regulation Of Actin Filament-based Process Positive Regulation Of Interferon-gamma Secretion Regulation Of Cytoskeleton Organization Movement Of Cell Or Subcellular Component Fc-gamma Receptor Signaling Pathway Involved In Phagocytosis Fc-gamma Receptor Signaling Pathway Fc Receptor Mediated Stimulatory Signaling Pathway Actin Cytoskeleton Organization Actin Filament-based Movement Actin Filament-based Process Mitotic Cell Cycle Process Substrate-dependent Cell Migration, Cell Extension Cellular Component Assembly Regulation Of Oxidoreductase Activity Regulation Of Cellular Component Organization Mitotic Cell Cycle Signaling Actin Polymerization Or Depolymerization Cytoskeleton Organization Cell Communication Phagocytosis Fc Receptor Signaling Pathway Immune Response-activating Cell Surface Receptor Signaling Pathway Immune System Process Signal Transduction Rac Protein Signal Transduction Cell Projection Assembly Actin Filament Organization Mitotic Nuclear Division Nitric Oxide Metabolic Process Regulation Of Catalytic Activity Reactive Nitrogen Species Metabolic Process Endocytosis Cell Cycle Process Immune Response-regulating Cell Surface Receptor Signaling Pathway Transmembrane Receptor Protein Tyrosine Kinase Signaling Pathway Regulation Of Endothelial Cell Apoptotic Process Cellular Response To Stimulus Cell Surface Receptor Signaling Pathway Substrate-dependent Cell Migration Organelle Organization Positive Regulation Of Organelle Organization Regulation Of Nitric-oxide Synthase Activity	Cell Cycle Process Regulation Of Protein Export From Nucleus Nuclear Envelope Disassembly Establishment Of Chromosome Localization Cell Cycle Nuclear Envelope Organization Chromosome Localization To Nuclear Envelope Involved In Synapsis Spliceosomal Complex Disassembly Histone H2B Conserved C-terminal Lysine Ubiquitination Negative Regulation Of Intracellular Protein Transport Regulation Of Fas Signaling Pathway Negative Regulation Of Sequence-specific DNA Binding Transcription Factor Activity Negative Regulation Of Intracellular Transport Nucleus Organization Organelle Organization Protein Ubiquitination Protein Modification By Small Protein Conjugation Positive Regulation Of Axon Regeneration Negative Regulation Of Protein Export From Nucleus Retrograde Axon Cargo Transport Negative Regulation Of Protein Transport Mitotic Cell Cycle Process Intracellular Receptor Signaling Pathway Positive Regulation Of Neuron Projection Regeneration Activation Of Cdc42 GTPase Activity Histone H2B Ubiquitination Mitotic Cell Cycle Regulation Of Nucleocytoplasmic Transport Mitotic Nuclear Envelope Reassembly Mitotic Centrosome Separation Chromosome Segregation Neurofilament Cytoskeleton Organization Innate Immune Response Centrosome Separation Toll Signaling Pathway Negative Regulation Of Catenin Import Into Nucleus Nuclear Envelope Reassembly Cellular Response To DNA Damage Stimulus DNA Damage Response, Signal Transduction By P53 Class Mediator Resulting In Transcription Of P21 Class Mediator Regulation Of Intracellular Protein Transport DNA Damage Response, Signal Transduction Resulting In Transcription Regulation Of Axon Regeneration Positive Regulation Of Protein Export From Nucleus Positive Regulation Of Macroautophagy Positive Regulation Of Cdc42 GTPase Activity
Tagcloud ?		adipocyte biologically chick chicken chickens cutoff experimentally klf5 lpin1 luciferase map3k7 mettl14 microrna mir miranda mirna pck2 pdcd5 pycr2 slc2a2 splenocytes tardbp tnfsf10 transcriptionally tumourigenesis ube2e3 ubiquitously utrs vertebrate	amplified approximate blotting construct constructed digested digestion egfp eukaryotic flag fluorescence foundation frame green hek293 inserted kd mononuclear pires2 plasmid precipitation reading restriction sali successfully tag teracting transfected xhoi
Tagcloud (Difference) ?		adipocyte biologically chick chicken chickens cutoff experimentally klf5 lpin1 luciferase map3k7 mettl14 microrna mir miranda mirna pck2 pdcd5 pycr2 slc2a2 splenocytes tardbp tnfsf10 transcriptionally tumourigenesis ube2e3 ubiquitously utrs vertebrate	amplified approximate blotting construct constructed digested digestion egfp eukaryotic flag fluorescence foundation frame green hek293 inserted kd mononuclear pires2 plasmid precipitation reading restriction sali successfully tag teracting transfected xhoi
Tagcloud (Intersection) ?