AIP and GNA13

Number of citations of the paper that reports this interaction (PubMedID 19390533)
25

Data Source:
BioGRID (two hybrid)

		AIP	GNA13
Description		AHR interacting HSP90 co-chaperone	G protein subunit alpha 13
Image
GO Annotations	Cellular Component	Nucleoplasm Cytoplasm Cytosol Plasma Membrane Membrane Aryl Hydrocarbon Receptor Complex	Nucleus Cytoplasm Cytosol Heterotrimeric G-protein Complex Plasma Membrane Focal Adhesion Membrane Brush Border Membrane Melanosome Extracellular Exosome Postsynapse
	Molecular Function	Transcription Coregulator Activity Transcription Coactivator Activity Peptidyl-prolyl Cis-trans Isomerase Activity Protein Binding Aryl Hydrocarbon Receptor Binding GAF Domain Binding Unfolded Protein Binding	Nucleotide Binding G Protein-coupled Receptor Binding GTPase Activity G Protein Activity Guanyl-nucleotide Exchange Factor Activity Protein Binding GTP Binding Guanyl Nucleotide Binding G-protein Beta/gamma-subunit Complex Binding D5 Dopamine Receptor Binding Metal Ion Binding
	Biological Process	Protein Targeting To Mitochondrion Xenobiotic Metabolic Process Positive Regulation Of DNA-templated Transcription Protein Maturation	Angiogenesis Branching Involved In Blood Vessel Morphogenesis In Utero Embryonic Development Signal Transduction G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Rho Protein Signal Transduction Regulation Of Blood Pressure Regulation Of Cell Shape Regulation Of Fibroblast Migration Cell Differentiation Platelet Activation Intracellular Signal Transduction Regulation Of Small GTPase Mediated Signal Transduction Regulation Of Postsynapse Assembly Rho-activating G Protein-coupled Receptor Signaling Pathway
Pathways		Aryl hydrocarbon receptor signalling Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation	NRAGE signals death through JNK G alpha (12/13) signalling events Thromboxane signalling through TP receptor Thrombin signalling through proteinase activated receptors (PARs) Thrombin signalling through proteinase activated receptors (PARs) CDC42 GTPase cycle RAC1 GTPase cycle
Drugs
Diseases
GWAS		Apolipoprotein A1 levels ( 32203549) Mean corpuscular hemoglobin ( 32888494) Mean reticulocyte volume ( 32888494) Refractive error ( 32231278) Urate levels ( 31578528)	Brain morphology (MOSTest) ( 32665545) Periventricular white matter hyperintensities ( 32517579) White matter microstructure (global fractional anisotropy) ( 24736177)
Interacting Genes		22 interacting genes: AHR ARNT BTG3 CEBPA CLEC7A CSNK2A1 EGFR ERBB2 GNA13 GNAQ HSP90AA1 HTR6 HUNK IKBKG IRF7 LCOR PDE4A PPARA PTGES3 STIP1 TNNI3K TOMM20	31 interacting genes: AIP AKAP3 ARHGEF1 ARHGEF11 ARHGEF12 CDH1 CDH2 CTNNB1 CXCR4 DRD5 EDNRB F2R GNA12 GPR17 MCF2 MTNR1A PPP5C PRKACA PRKCB PRKCD PRKCE PTK2B RDX RGS16 RIC8A S1PR2 S1PR3 S1PR4 TBXA2R TGFBR1 TSHR
Entrez ID		9049	10672
HPRD ID		10408	05100
Ensembl ID		ENSG00000110711	ENSG00000120063
Uniprot IDs		A0A804HJ38 A0A804HKL7 O00170	Q14344
PDB IDs		2LKN 4AIF 4APO 7ZUB 8QMO	7SF7 7SF8 7T6B 7YDH 8H8J 8KGG 8ZX4 8ZX5 9GE2 9GE3 9IY8 9IZH
Enriched GO Terms of Interacting Partners?		Hsp90 Protein Binding Nuclear Aryl Hydrocarbon Receptor Complex Signal Transduction Intracellular Signal Transduction Embryonic Placenta Development Protein Folding Chaperone Complex Telomerase Holoenzyme Complex Assembly Protein-containing Complex Nuclear Receptor Activity Aryl Hydrocarbon Receptor Complex Intestinal Epithelial Structure Maintenance ERBB2-EGFR Signaling Pathway Positive Regulation Of Protein Metabolic Process Regulation Of Defense Response Positive Regulation Of Catabolic Process Protein Heterodimerization Activity Positive Regulation Of Nucleobase-containing Compound Metabolic Process RNA Polymerase II-specific DNA-binding Transcription Factor Binding Regulation Of Signal Transduction Positive Regulation Of Macromolecule Biosynthetic Process Positive Regulation Of Macromolecule Metabolic Process Nucleus Cis-regulatory Region Sequence-specific DNA Binding Positive Regulation Of Biosynthetic Process Intracellular Receptor Signaling Pathway Guanyl Nucleotide Binding Protein Stabilization Ruffle Membrane Positive Regulation Of Metabolic Process Regulation Of Cell Communication Regulation Of Signaling Protein Kinase Activity G-protein Beta/gamma-subunit Complex Binding G Protein-coupled Serotonin Receptor Signaling Pathway Chaperone-mediated Protein Complex Assembly Telomere Maintenance Via Telomerase DNA Polymerase Binding ERBB2 Signaling Pathway Positive Regulation Of Telomere Maintenance Via Telomerase Unfolded Protein Binding Regulation Of Multicellular Organismal Process Maintenance Of Gastrointestinal Epithelium Protein Import Into Mitochondrial Matrix Response To Xenobiotic Stimulus Regulation Of Intracellular Signal Transduction RNA-templated DNA Biosynthetic Process Positive Regulation Of Telomere Maintenance Via Telomere Lengthening Regulation Of Immune System Process Positive Regulation Of Signal Transduction Regulation Of Cell Population Proliferation	G Protein-coupled Receptor Signaling Pathway Signal Transduction Plasma Membrane Adenylate Cyclase-modulating G Protein-coupled Receptor Signaling Pathway Membrane G Protein-coupled Receptor Activity Adenylate Cyclase-activating G Protein-coupled Receptor Signaling Pathway Regulation Of Intracellular Signal Transduction Regulation Of Signal Transduction Regulation Of Cell Communication Regulation Of Signaling Cellular Response To Oxygen-containing Compound Intracellular Signal Transduction Rho-activating G Protein-coupled Receptor Signaling Pathway Intracellular Signaling Cassette G Protein-coupled Receptor Binding Sphingosine-1-phosphate Receptor Activity Adenylate Cyclase-inhibiting G Protein-coupled Receptor Signaling Pathway Regulation Of Body Fluid Levels Positive Regulation Of Vasculature Development Peptidyl-serine Phosphorylation Positive Regulation Of Signal Transduction Modulation Of Chemical Synaptic Transmission Guanyl-nucleotide Exchange Factor Activity Sphingosine-1-phosphate Receptor Signaling Pathway Positive Regulation Of Intracellular Signal Transduction Sphingolipid Mediated Signaling Pathway Diacylglycerol-dependent Serine/threonine Kinase Activity Positive Regulation Of Cell Communication Positive Regulation Of Signaling Rho Protein Signal Transduction Positive Regulation Of Cytosolic Calcium Ion Concentration Response To Lipid Cell Motility Regulation Of Multicellular Organismal Process Regulation Of Blood Pressure Regulation Of Release Of Sequestered Calcium Ion Into Cytosol Regulation Of Small GTPase Mediated Signal Transduction Regulation Of MAPK Cascade Catenin Complex Cell Surface Receptor Signaling Pathway Protein Kinase C Signaling Diacylglycerol-dependent, Calcium-independent Serine/threonine Kinase Activity G-protein Alpha-subunit Binding Cell Migration Lamellipodium Regulation Of Protein Localization Regulation Of Vasculature Development Regulation Of Developmental Process Cellular Response To Indole-3-methanol
Tagcloud ?
Tagcloud (Difference) ?
Tagcloud (Intersection) ?